2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

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Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N0379S14
    D-Mannose-13C,d
    D-Mannose-13C,d is the deuterium and 13C labeled D-Mannose. D-Mannose is a carbohydrate, which plays an important role in human metabolism, especially in the glycosylationof specific prote[1][2].
    D-Mannose-<sup>13</sup>C,d
  • HY-W009300S1
    4-Hydroxyestrone-13C6
    4-Hydroxyestrone-13C6 is a 13C-labeled Hypoxanthine. Hypoxanthine, a purine derivative, is a potential free radical generator and could be used as an indicator of hypoxia.
    4-Hydroxyestrone-<sup>13</sup>C<sub>6</sub>
  • HY-128738S
    Thymidine-5'-monophosphate-13C10,15N2 disodium
    Thymidine-5'-monophosphate-13C10,15N2 (disodium) is the 13C and 15N labeled Thymidine-5'-monophosphate disodium salt[1]. Thymidine-5'-monophosphate disodium salt is an endogenous metabolite.
    Thymidine-5'-monophosphate-<sup>13</sup>C<sub>10</sub>,<sup>15</sup>N<sub>2</sub> disodium
  • HY-W017018S1
    L-Ornithine-1,2-13C2 hydrochloride
    L-Ornithine-1,2-13C2 (hydrochloride) is the 13C-labeled L-Ornithine hydrochloride. L-Ornithine hydrochloride is a free amino acid that plays a central role in the urea cycle and is also important for the disposal of excess nitrogen.
    L-Ornithine-1,2-<sup>13</sup>C<sub>2</sub> hydrochloride
  • HY-19700R
    trans-Zeatin (Standard)
    trans-Zeatin (Standard) is the analytical standard of trans-Zeatin. This product is intended for research and analytical applications. trans-Zeatin is a plant cytokinin, which plays an important role in cell growth, differentiation, and division; trans-Zeatin also inhibits UV-induced MEK/ERK activation.
    trans-Zeatin (Standard)
  • HY-P2818D
    Alkaline phosphatase, Human liver
    Alkaline phosphatase (Apase), Human liver is a glycoprotein bound to plasma membranes that hydrolyzes several monophosphate esters optimally at an alkaline pH with the release of inorganic phosphates.
    Alkaline phosphatase, Human liver
  • HY-N1495R
    Maltopentaose (Standard)
    Maltopentaose (Standard) is the analytical standard of Maltopentaose. This product is intended for research and analytical applications. Maltopentaose is the shortest chain oligosaccharide that can be classified as maltodextrin and is also used in a study to investigate glycation and phosphorylation of α-lactalbumin.
    Maltopentaose (Standard)
  • HY-130365
    Tixocortol pivalate
    Tixocortol pivalate is a corticosteroid with some anti-inflammatory activity.
    Tixocortol pivalate
  • HY-N0832S1
    L-Histidine-13C6,15N3
    L-Histidine-13C6,15N3 is 13C and 15N-labeled L-Histidine (HY-N0832). L-Histidine is an essential amino acid for infants. L-Histidine is an inhibitor of mitochondrial glutamine transport.
    L-Histidine-13C6,15N3
  • HY-W018772S3
    D-Ribose-13C-2
    D-Ribose-13C-2 is the 13C labeled D-Ribose. D-Ribose is an energy enhancer, and acts as a sugar moiety of ATP, and widely used as a metabolic therapy supplement for chronic fatigue syndrome or cardiac energy metabolism. D-Ribose is active in protein glyca
    D-Ribose-<sup>13</sup>C-2
  • HY-137868A
    Decanoyl coenzyme A triammonium
    Decanoyl coenzyme A (Decanoyl CoA) triammonium is a primer for the fatty acid elongation system in Mycobacterium smegmat.
    Decanoyl coenzyme A triammonium
  • HY-P2989
    Pyruvate carboxylase
    Pyruvate carboxylase is a biotin-containing enzyme that catalyzes the HCO3− and MgATP dependent carboxylation of pyruvate to form oxaloacetate. Pyruvate carboxylase plays an essential role in controlling whole-body energetics through regulation of gluconeogenesis in the liver, synthesis of fatty acids in adipocytes, and insulin secretion in pancreatic β cells.
    Pyruvate carboxylase
  • HY-124353
    11-Dehydro thromboxane B3
    11-Dehydro thromboxane B3 (11-Dehydro-TXB3) is a urinary metabolite of Thromboxane A3 (TXA3).
    11-Dehydro thromboxane B3
  • HY-W007888R
    2-Hydroxy-4-methylbenzaldehyde (Standard)
    Prostaglandin E1 (Standard) is the analytical standard of Prostaglandin E1. This product is intended for research and analytical applications. Prostaglandin E1 (Alprostadil) is a prostanoid receptor ligand, with Kis of 1.1 nM, 2.1 nM, 10 nM, 33 nM and 36 nM for mouse EP3, EP4, EP2, IP and EP1, respectively. Prostaglandin E1 induces vasodilation and inhibits platelet aggregation. Prostaglandin E1 can be used as a vasodilator for the research of peripheral vascular diseases.
    2-Hydroxy-4-methylbenzaldehyde (Standard)
  • HY-129546
    Eprozinol hydrochloride
    Eprozinol hydrochloride is a compound with antibronchoconstrictor activity. Eprozinol hydrochloride can be used in the study of bronchospasm.
    Eprozinol hydrochloride
  • HY-N0379S18
    D-Mannose-13C6,d7
    D-mannose-13C6,d7 is the deuterium and 13C labeled D-Mannose. D-Mannose is a carbohydrate, which plays an important role in human metabolism, especially in the glycosylationof specific prote[1][2].
    D-Mannose-<sup>13</sup>C<sub>6</sub>,d<sub>7</sub>
  • HY-N0210S2
    D-Galactose-13C-3
    D-Galactose-13C-3 is the 13C labeled D-Galactose. D-Galactose is a natural aldohexose and C-4 epimer of glucose[1][2][3][4].
    D-Galactose-<sup>13</sup>C-3
  • HY-B0442AS
    Vardenafil-d5 hydrochloride
    Vardenafil-d5 hydrochloride is deuterated labeled Vardenafil hydrochloride (HY-B0442A). Vardenafil hydrochloride is a selective and orally active inhibitor of phosphodiesterase-5 (PDE5), with an IC50 of 0.7 nM. Vardenafil hydrochloride shows inhibitory towards PDE1, PDE6 with IC50s of 180 nM, and 11 nM, while IC50s are >1000 nM for PDE3 and PDE4. Vardenafil hydrochloride competitively inhibits cyclic guanosine monophosphate (cGMP) hydrolysis and thus increases cGMP levels. Vardenafil hydrochloride can be used for the research of erectile dysfunction, hepatitis, diabetes[1]-[6].
    Vardenafil-d<sub>5</sub> hydrochloride
  • HY-111487
    α-Methylacyl-CoA racemase 1
    α-methylacyl-CoA racemase 1 is an enzyme that catalyzes a key chiral inversion step in the metabolism of branched-chain fatty acids, and used as a maker in prostate and other cancer.
    α-Methylacyl-CoA racemase 1
  • HY-44134R
    Dimethyl 2-oxoglutarate (Standard)
    Felypressin (Standard) is the analytical standard of Felypressin. This product is intended for research and analytical applications. Felypressin (PLV-2) is a non-catecholamine vasoconstrictor and a vasopressin 1 agonist. Felypressin is widely used in dental procedures.
    Dimethyl 2-oxoglutarate (Standard)
Cat. No. Product Name / Synonyms Application Reactivity