2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

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Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N7092S7
    D-Fructose-6-13C
    		≥98.0%
    D-Fructose-6-13C is the 13C labeled D-Fructose. D-Fructose (D(-)-Fructose) is a naturally occurring monosaccharide found in many plants[1].
    D-Fructose-6-<sup>13</sup>C
  • HY-N0210S9
    D-Galactose-d2
    D-Galactose-d2 is the deuterium labeled D-Galactose. D-Galactose is a natural aldohexose and C-4 epimer of glucose.
    D-Galactose-d<sub>2</sub>
  • HY-120958
    Nisinic acid
    Nisinic acid (C24:6n-3) is a very long chain polyunsaturated fatty acid (VLCPUFA) that is a component of triglycerides and cholesterol esters in mouse and rat testis.
    Nisinic acid
  • HY-117578
    KB 5666
    KB 5666 is a benzoxazine derivative with lipid peroxidation inhibitory activity. KB 5666 showed protective effects against post-ischemic neuronal death. KB 5666 effectively protected CA1 neurons when injected 5 minutes before or immediately after ischemia. KB 5666 also showed a dose-dependent protective effect when injected within 1 hour after ischemia. KB 5666 effectively prevented the significant decrease in microtubule-associated protein 2 immunoreactivity within the dendritic field of CA1 pyramidal cells. KB 5666 prevented the decrease in [3H]PDBu binding activity in different layers of the CA1 region after ischemia. The application of KB 5666 showed the ability to improve the cellular and functional consequences of ischemia.
    KB 5666
  • HY-P2866
    β-N-Acetylhexosaminidase, Streptococcus pneumoniae
    β-N-Acetylhexosaminidase (EC 3.2.1.52) is an exoglycosidase that catalyzes the hydrolysis of terminal non-reducing β-N-acetylgalactosamine and glucosamine residues in oligosaccharides for epigenetic applications.
    β-N-Acetylhexosaminidase, Streptococcus pneumoniae
  • HY-125848R
    Ginsenoside F2 (Standard)
    Ginsenoside F2 (Standard) is the analytical standard of Ginsenoside F2. This product is intended for research and analytical applications. Ginsenoside F2, a metabolite from Ginsenoside Rb1, induces apoptosis accompanied by protective autophagy in breast cancer stem cells.
    Ginsenoside F2 (Standard)
  • HY-B0228S3
    Adenosine-3′-13C
    Adenosine-3′-13C is the 13C labeled Adenosine. Adenosine (Adenine riboside), a ubiquitous endogenous autacoid, acts through the enrollment of four G protein-coupled receptors: A1, A2A, A2B, and A3. Adenosine affects almost all aspects of cellular physiolo
    Adenosine-3′-<sup>13</sup>C
  • HY-N0473S6
    L-Tyrosine-3,5-13C2
    		99.43%
    L-Tyrosine-3,5-13C2 is the 13C-labeled L-Tyrosine. L-Tyrosine is a non-essential amino acid which can inhibit citrate synthase activity in the posterior cortex.
    L-Tyrosine-3,5-<sup>13</sup>C<sub>2</sub>
  • HY-128743R
    12-Hydroxydodecanoic acid (Standard)
    Methyl isoeugenol (Standard) is the analytical standard of Methyl isoeugenol. This product is intended for research and analytical applications. Methyl isoeugenol (MIE) is a natural food flavour that can be isolated from Pimenta pseudocaryophyllus leaf. Methyl isoeugenol shows anxiolytic and antidepressant like effects. Methyl isoeugenol is orally active.
    12-Hydroxydodecanoic acid (Standard)
  • HY-113338A
    8-Hydroxyguanine hydrochloride
    8-Hydroxyguanine hydrochloride is a DNA damage product under oxidative stress, which is formed when hydroxyl radicals attack guanine in DNA. 8-Hydroxyguanine hydrochloride induces mutagenesis and leads to a transversion from G to T. 8-Hydroxyguanine hydrochloride is a marker of DNA oxidative damage.
    8-Hydroxyguanine hydrochloride
  • HY-E70328
    Alkalophilic Proteinase, Streptomyces sp
    Alkalophilic Proteinase, Streptomyces sp is a biocatalyst and a key enzyme in new biocatalyst technology. Enzyme engineering focuses on enhancing enzyme reaction kinetics, substrate selectivity, and activity under harsh conditions such as low or high pH. By introducing stimulus responsiveness to these enzyme modifications, dynamic control of activity is also possible.
    Alkalophilic Proteinase, Streptomyces sp
  • HY-N0059S5
    D-Arabinose-d5
    D-Arabinose-d5 is the deuterium labeled D-arabinose. D-arabinose is an endogenous metabolite[1].
    D-Arabinose-d<sub>5</sub>
  • HY-E70163
    Carbohydrate Sulfotransferase 3
    Carbohydrate Sulfotransferase 3 (EC:2.8.2.17) can catalyze sulphate transfer to position 6 of GalNAc residue of chondroitin.
    Carbohydrate Sulfotransferase 3
  • HY-113405S
    21-Desoxycortisol-d4
    21-Desoxycortisol-d4 is the deuterium labeled 21-Desoxycortisol[1].
    21-Desoxycortisol-d<sub>4</sub>
  • HY-117679
    LY 135114 free base
    LY 135114 free base is a metabolite with antitumor activity. LY 135114 free base is a metabolite of LY 195448, a phenylethanolamine compound with antitumor activity. LY 135114 free base has shown potential biological activity in research and may be used for cancer inhibition.
    LY 135114 free base
  • HY-145537
    1,3-Dipalmitoyl-2-eicosapentaenoyl glycerol
    1,3-Dipalmitoyl-2-eicosapentaenoyl glycerol is a positional isomer of triglyceride that can affect lipid metabolism.
    1,3-Dipalmitoyl-2-eicosapentaenoyl glycerol
  • HY-134129
    Benzoyl coenzyme A
    Benzoyl coenzyme A (Benzoyl CoA) is A derivative of Coenzyme A (CoA) in which the mercaptan group of CoA binds to the benzoyl group. Benzoyl coenzyme A is involved in the catalytic reaction as a substrate for the acyl transfer reaction. Benzoyl coenzyme A is a versatile metabolic intermediate that can be used to reveal substrate specificity of enzymes, metabolic regulation, and drug metabolism.
    Benzoyl coenzyme A
  • HY-B0539R
    Desloratadine (Standard)
    Desloratadine (Standard) is the analytical standard of Desloratadine. This product is intended for research and analytical applications. Desloratadine (Sch34117) is the orally active major metabolite of the nonsedating H1-antihistamine Loratadine. Desloratadine is a selective H1-receptor antagonist that has anti-allergic and anti-inflammatory activities.
    Desloratadine (Standard)
  • HY-19696S1
    Tauroursodeoxycholate-d4
    Tauroursodeoxycholate-d4 is deuterium labeled Tauroursodeoxycholate. Tauroursodeoxycholate (Tauroursodeoxycholic acid) is an endoplasmic reticulum (ER) stress inhibitor. Tauroursodeoxycholate significantly reduces expression of apoptosis molecules, such as caspase-3 and caspase-12. Tauroursodeoxycholate also inhibits ERK.
    Tauroursodeoxycholate-d<sub>4</sub>
  • HY-115899
    Malonyl CoA
    Malonyl CoA is a substrate for fatty acid biosynthesis and an inhibitor of fatty acid oxidation. Malonyl CoA is also a reversible inhibitor of mitochondrial carnitine palmitoyltransferase (CPT) 1.
    Malonyl CoA
Cat. No. Product Name / Synonyms Application Reactivity