2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

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Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N1446S4
    Oleic acid-13C-1
    Oleic acid-13C-1 is the 13C labeled Oleic acid (HY-N1446). Oleic acid (9-cis-Octadecenoic acid) is an abundant monounsaturated fatty acid. Oleic acid is a Na+/K+ ATPase activator.
    Oleic acid-<sup>13</sup>C-1
  • HY-18260S3
    Bisphenol A-d8
    Bisphenol A-d8 is the deuterium labeled Bisphenol A[1]. Bisphenol A is a phenolic, organic synthetic compound widely used in the production of polycarbonate plastics and epoxy resins. Bisphenol A is a reproductive, developmental, and systemic toxicant, often classified as an endocrine-disrupting compound (EDC). Bisphenol A is associated with many diseases, including cardiovascular diseases, respiratory diseases, diabetes, kidney diseases, obesity, and reproductivedisorders[2][3][4].
    Bisphenol A-d<sub>8</sub>
  • HY-14314
    ABT-418
    ABT-418 is a selective neuronal nicotinic acetylcholine receptor ligand with activity in improving spatial memory. ABT-418 administered before training can significantly reduce the spatial discrimination deficit caused by ventricular damage. ABT-418 is considered to be a potential treatment for attention deficit disorder.
    ABT-418
  • HY-113261R
    Oleoylcarnitine (Standard)
    Oleoylcarnitine (Standard) is the analytical standard of Oleoylcarnitine. This product is intended for research and analytical applications. Oleoylcarnitine, the metabolite which accumulates through suppression of fatty acid β-oxidation, can enhance hepatocarcinogenesis via STAT3 activation.
    Oleoylcarnitine (Standard)
  • HY-113359AS3
    Uridine 5'-diphosphate-15N2 dilithium
    Uridine 5'-diphosphate-15N2 dilithium is 15N labeled Uridine 5'-diphosphate (HY-113359). Uridine 5'-diphosphate is a P2Y6 receptor agonist with an EC50 of 0.013 μM for human P2Y6 receptor.
    Uridine 5'-diphosphate-<sup>15</sup>N<sub>2</sub> dilithium
  • HY-N6746R
    Citrinin (Standard)
    Citrinin (Standard) is the analytical standard of Citrinin. This product is intended for research and analytical applications. Citrinin (NSC 186) is a mycotoxin that causes food contamination and has different toxic effects. Citrinin is an effective oral anticancer agent. Citrinin has various regulatory effects on mouse immune system, including regulating the number of immune cells, inducing apoptosis and autophagy of immune cells, altering toll-like receptor expression and cytokine production. Citrinin can induce oxidative stress and lead to early apoptosis of oocytes. Low doses of Citrinin have neuroprotective effects against glutamate-induced excitotoxicity in rat cortical neurons. In addition, Citrinin also has antibacterial activity.
    Citrinin (Standard)
  • HY-103298
    MNI-caged kainate
    MNI-caged kainate is a photoprotected neuroactive amino acid with the activity to generate large inward currents. MNI-caged kainate can be released at the resting membrane potential of Purkinje cells and generate significant inward currents. The release of MNI-caged kainate results in approximately 40% of the current being generated through AMPA receptor activation. MNI-caged kainate is used to study fast synaptic receptor mechanisms. The photorelease time of MNI-caged kainate is in the sub-microsecond range, making it suitable for investigating the mechanisms of fast synaptic transmission.
    MNI-caged kainate
  • HY-B0389S19
    D-Glucose-13C,d
    D-Glucose-13C,d is the deuterium and 13C labeled D-Glucose. D-Glucose (Glucose), a monosaccharide, is an important carbohydrate in biology. D-Glucose is a carbohydrate sweetener and critical components of the general metabolism, and serve as critical sign
    D-Glucose-<sup>13</sup>C,d
  • HY-N2406R
    Dihydrocaffeic acid (Standard)
    Ditalimfos (Standard) is the analytical standard of Ditalimfos. This product is intended for research and analytical applications. Ditalimfos is an organophosphate fungicide. Ditalimfos is mainly used in agriculture to control fungal diseases of crops. Ditalimfos can be used for fungal resistance studies and risk assessment of residues in the environment.
    Dihydrocaffeic acid (Standard)
  • HY-13211R
    (E)-2-Decenoic acid (Standard)
    (E)-2-Decenoic acid (Standard) is the analytical standard of (E)-2-Decenoic acid. This product is intended for research and analytical applications. (E)-2-Decenoic acid is an interesting fatty acid isolated from royal jelly secretions of honey bees.
    (E)-2-Decenoic acid (Standard)
  • HY-N1944R
    Nerolidol (Standard)
    Nerolidol (Standard) is the analytical standard of Nerolidol. This product is intended for research and analytical applications. Nerolidol has multiple natural membrane activities, possesses anti-cancer, anti-inflammatory, antibacterial and anti-insect activity. Nerolidol Suppresses parasitic activity, suppresses bloodsucking diseases, bloodworm diseases, and other diseases. Nerolidol can protect the cells from lipid and protein properties, damage to DNA, and protect the cells from damage.
    Nerolidol (Standard)
  • HY-W010589R
    H-Abu-OH (Standard)
    H-Abu-OH (Standard) is the analytical standard of H-Abu-OH. This product is intended for research and analytical applications. H-Abu-OH, one of the three isomers of aminobutyric acid, is elevated in the plasma of children with with Reye's syndrome, tyrosinemia, homocystinuria, nonketotic hyperglycinemia, and ornithine transcarbamylase deficiency.
    H-Abu-OH (Standard)
  • HY-18341S1
    Thyroxine hydrochloride-13C6
    Thyroxine hydrochloride-13C6 is the 13C-labeled L-Thyroxine. L-Thyroxine (Levothyroxine; T4) is a synthetic hormone for the research of hypothyroidism. DIO enzymes convert biologically active thyroid hormone (Triiodothyronine,T3) from L-Thyroxine (T4)[1].
    Thyroxine hydrochloride-<sup>13</sup>C<sub>6</sub>
  • HY-117713
    Cycloechinulin
    Cycloechinulin is a diketopiperazine fungal metabolite.
    Cycloechinulin
  • HY-N0830S20
    Palmitic acid-d9
    Palmitic acid-d9 is the deuterium labeled Palmitic acid. Palmitic acid is a long-chain saturated fatty acid commonly found in both animals and plants. PA can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells[1][2].
    Palmitic acid-d<sub>9</sub>
  • HY-W753671
    2,6-Diaminoheptanedioic acid-13C7
    2,6-Diaminoheptanedioic Acid-13C7 is a 13C7 labeled version of 2,6-Diaminoheptanedioic acid (HY-128746). 2,6-Diaminoheptanedioic acid is an endogenous metabolite.
    2,6-Diaminoheptanedioic acid-<sup>13</sup>C<sub>7</sub>
  • HY-156399
    KR-27425
    		Activator
    AChE activator 1 (compound 13) is a non-pyridinium oxime reactivator of paraoxon-inhibited acetylcholinesterase(AChE).
    KR-27425
  • HY-128750
    (Z)-4-Amino-4-oxobut-2-enoic acid
    		99.81%
    (Z)-4-Amino-4-oxobut-2-enoic acid is an endogenous metabolite.
    (Z)-4-Amino-4-oxobut-2-enoic acid
  • HY-128753S4
    D-Lyxose-13C-3
    D-Lyxose-13C-3 is the 13C labeled D-Lyxose. D-Lyxose is an endogenous metabolite[1].
    D-Lyxose-<sup>13</sup>C-3
  • HY-125523
    Fumiquinazoline D
    Fumiquinazoline D, a secondary metabolite, is a mycotoxin.
    Fumiquinazoline D
Cat. No. Product Name / Synonyms Application Reactivity