2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

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Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-B1331S1
    Cyromazine-13C3
    Cyromazine-13C3 is the 13C3 labeled Cyromazine. Cyromazine is a triazine insect growth regulator used as an insecticide and an acaricide. It is a cyclopropyl derivative of melamine. Cyromazine works by affecting the nervous system of the immature larval stages of certain insects.
    Cyromazine-<sup>13</sup>C<sub>3</sub>
  • HY-W004464S
    2-(1-Piperazinyl)pyrimidine-d8
    2-(1-Piperazinyl)pyrimidine-d8 is deuterium labeled 2-(1-Piperazinyl)pyrimidine.
    2-(1-Piperazinyl)pyrimidine-d<sub>8</sub>
  • HY-W013353
    (RS)-Salsolinol hydrobromide
    (RS)-Salsolinol hydrobromide is the hydrobromide form of (±)-Salsolinol (HY-113316). (RS)-Salsolinol hydrobromide is a Dopamine (HY-B0451)-derived endogenous metabolite. (RS)-Salsolinol hydrobromide activates μ-opioid receptors (MORs), reduces GABAergic transmission, increases the excitability of dopamine (DA) neurons, and thus accelerates the sustained firing of neurons in the posterior ventral tegmental area (pVTA).
    (RS)-Salsolinol hydrobromide
  • HY-W015464R
    N-Isovaleroylglycine (Standard)
    N-Isovaleroylglycine (Standard) is the analytical standard of N-Isovaleroylglycine. This product is intended for research and analytical applications. N-Isovaleroylglycine is an acyl glycine and could be used as a biomarker for the predispositon for weight gain and obesity.
    N-Isovaleroylglycine (Standard)
  • HY-128754R
    Monoolein (Standard)
    Monoolein is a biocompatible lipid molecule that can be used as a carrier for bone repair. Monoolein exhibits anti-inflammatory activity by inhibiting the immune response induced by LPS (HY-D1056). It exerts its anti-inflammatory effects by reducing the production of immune response factors such as IL-12 p40, IL-6, and TNF-α, and inhibiting the generation of NO. Monoolein can be used in drug delivery and research in the field of inflammatory diseases .
    Monoolein (Standard)
  • HY-P2888C
    Bilirubin oxidase, Bacillus pumilus
    Bilirubin oxidase (BOD), Bacillus pumilus is a multicopper oxidase that catalyzes the oxidation of bilirubin to biliverdin, as well as other tetrapyrrole, phenols, and aryl diamines. Bilirubin oxidase, Bacillus pumilus can serve as a single-enzyme deoxygenator, catalyzing the direct reduction of oxygen to water in the presence of electron donor substrates, without releasing hydrogen peroxide. Bilirubin oxidase, Bacillus pumilus can be used to develop enzyme-based biosensors.
    Bilirubin oxidase, Bacillus pumilus
  • HY-W012479S
    H-D-Trp-OH-d5
    H-D-Trp-OH-d5 (D-Tryptophan-d5) is the deuterium labeled H-D-Trp-OH. H-D-Trp-OH is a D-stereoisomer of tryptophan and occasionally found in naturally produced peptides such as the marine venom peptide.
    H-D-Trp-OH-d<sub>5</sub>
  • HY-113479
    20-Hydroxy-leukotriene B4
    20-Hydroxy-leukotriene B4 is an endogenous metabolite present in Urine that can be used for the research of Sjogren Larsson Syndrome.
    20-Hydroxy-leukotriene B4
  • HY-N7092S6
    D-Fructose-5-13C
    D-Fructose-5-13C is the 13C labeled D-Fructose. D-Fructose (D(-)-Fructose) is a naturally occurring monosaccharide found in many plants[1].
    D-Fructose-5-<sup>13</sup>C
  • HY-W011873R
    Palmitoleic acid (Standard)
    Pazopanib (Hydrochloride) (Standard) is the analytical standard of Pazopanib (Hydrochloride). This product is intended for research and analytical applications. Pazopanib Hydrochloride (GW786034 Hydrochloride) is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFRβ, c-Kit, FGFR1, and c-Fms with an IC50 of 10, 30, 47, 84, 74, 140 and 146 nM, respectively.
    Palmitoleic acid (Standard)
  • HY-N6217
    F-14329
    F-14329 is a tetramic acid fungal metabolite.
    F-14329
  • HY-E70312
    CalB-10Xup
    CalB-10Xup (Candida antarctica lipase) is a biocatalyst and a key enzyme in new biocatalyst technology. Enzyme engineering focuses on enhancing enzyme reaction kinetics, substrate selectivity, and activity under harsh conditions such as low or high pH. By introducing stimulus responsiveness to these enzyme modifications, dynamic control of activity is also possible.
    CalB-10Xup
  • HY-B1000AR
    L-SelenoMethionine (Standard)
    L-SelenoMethionine (Standard) is the analytical standard of L-SelenoMethionine. This product is intended for research and analytical applications. L-SelenoMethionine, an L-isomer of Selenomethionine, is a major natural food-form of selenium. L-SelenoMethionin is a cancer chemopreventive agent that can reduce cancer incidence by dietary supplementation and induce apoptosis of cancer cells. L-SelenoMethionine also can increase expression of glutathione peroxidase.
    L-SelenoMethionine (Standard)
  • HY-112353
    NP603
    NP603 is a potent inhibitor of FGF receptor 1, exhibiting remarkable activity against endothelial proliferation in HUVEC cells stimulated by rhFGF-2, with a minimum effective dose of 0.4 microM.
    NP603
  • HY-N1150S10
    Thymidine-d14
    Thymidine-d14 (DThyd-d14; NSC 21548-d14) is deuterium labeled Thymidine (HY-N1150). Thymidine, a specific precursor of deoxyribonucleic acid, is used as a cell synchronizing agent. Thymidine is a DNA synthesis inhibitor that can arrest cell at G1/S boundary, prior to DNA replication.
    Thymidine-d<sub>14</sub>
  • HY-127119
    Benanserin hydrochloride
    Benanserin hydrochloride is a serotonin antagonist with psychopharmacological activity. Benanserin hydrochloride can be used to study specific behavioral manifestations in monitoring systems for drug effects. The effects of Benanserin hydrochloride can be sensitively and effectively assessed, for example, by measuring muscle movement capacity and reaction time. Benanserin hydrochloride is suitable for monitoring specific muscle physiological changes. The biological activity of Benanserin hydrochloride can provide reproducible bioassay parameters for experiments.
    Benanserin hydrochloride
  • HY-113000
    Cetoleic acid
    Cetoleic acid is a long-chain monounsaturated fatty acid found in deep-sea fish. Cetoleic acid can promote the synthesis of ALA in human HepG2 cells and EPA in vitro in salmon liver cells, affecting cholesterol levels in rodents. Cetoleic acid has potential applications in cardiovascular disease research.
    Cetoleic acid
  • HY-W007704
    Methyl cyclohexanecarboxylate
    		99.29%
    Methyl cyclohexanecarboxylate is an endogenous metabolite.
    Methyl cyclohexanecarboxylate
  • HY-128532
    Formononetin 7-O-β-D-glucuronide
    Formononetin 7-O-β-D-glucuronide is a metabolite of Formononetin (HY-N0183) and can be absorbed and metabolized through the intestine.
    Formononetin 7-O-β-D-glucuronide
  • HY-W040040R
    γ-Cyclodextrin (Standard)
    γ-Cyclodextrin (Standard) is the analytical standard of γ-Cyclodextrin (HY-W040040). This product is intended for research and analytical applications. γ-Cyclodextrin is an orally active cyclic oligosaccharide composed of eight glucose molecules, which can be formed by bacteria digesting starch. γ-Cyclodextrin can form water-soluble inclusion complexes with a variety of poorly soluble compounds and is widely used in fields such as pharmacy and food. In addition, γ-Cyclodextrin has good safety.
    γ-Cyclodextrin (Standard)
Cat. No. Product Name / Synonyms Application Reactivity