2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

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Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W004784
    3-Butynoic acid
    		99.99%
    3-Butynoic acid is an inhibitor of acyl CoA dehydrogenase. 3-Butynoic acid is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    3-Butynoic acid
  • HY-113147A
    L-Palmitoylcarnitine chloride
    		≥98.0%
    L-Palmitoylcarnitine chloride, a long-chain acylcarnitine and a fatty acid metabolite, accumulates in the sarcolemma and deranges the membrane lipid environment during ischaemia. L-Palmitoylcarnitine chloride inhibits KATP channel activity, without affecting the single channel conductance, through interaction with Kir6.2.
    L-Palmitoylcarnitine chloride
  • HY-Y0351
    Phenylthiourea
    		99.64%
    Phenylthiourea (Phenylthiocarbamide) is an inhibitor for phenoloxidase. Phenylthiourea inhibits enzymatic oxidation of DOPA by phenoloxidase (Ki = 0.21 μM). Phenylthiourea is an effective inhibitor for tyrosinase. Phenylthiourea can lead to graying of hair in black rats due to the interference with melanin formation.
    Phenylthiourea
  • HY-B1472
    Deoxycorticosterone acetate
    		99.87%
    Deoxycorticosterone acetate (DOCA) is an adrenocortin, acts as a precursor to aldosterone. Deoxycorticosterone acetate is a mineralocorticoid receptor agonist. Deoxycorticosterone acetate can cause severe renal injury, including inflammation, fibrosis, glomerular damage, and proteinuria.
    Deoxycorticosterone acetate
  • HY-17577
    Berberine chloride hydrate
    		99.82%
    Berberine chloride hydrate (Natural Yellow 18 chloride hydrate) is an alkaloid that acts as an antibiotic. Berberine chloride hydrate induces reactive oxygen species (ROS) generation and inhibits DNA topoisomerase. Antineoplastic properties.
    Berberine chloride hydrate
  • HY-N0543
    Allantoin
    		98.87%
    Allantoin is a skin conditioning agent that promotes healthy skin, stimulates new and healthy tissue growth.
    Allantoin
  • HY-112530
    1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine
    		99.98%
    1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine (DSPE) is a phosphoethanolamine (PE) lipid that can be used in the synthesis of liposomes.
    1,2-Distearoyl-sn-glycero-3-phosphorylethanolamine
  • HY-106950A
    Fosfructose trisodium
    		≥98.0%
    Fosfructose trisodium (Diphosphofructose trisodium;Esafosfan trisodium;FDP trisodium) is a cytoprotective natural sugar phosphate for the potential treatment of cardiovascular ischemia, sickle cell anemia and asthma. It acts by stimulating anaerobic glycolysis which generates adenosine triphosphate under ischemic conditions.
    Fosfructose trisodium
  • HY-113427
    trans-Vaccenic acid
    		≥98.0%
    trans-Vaccenic acid is a naturally occurring trans fatty acid (TFA). trans-Vaccenic acid inhibits nasopharyngeal carcinoma (NPC) cell growth and induces apoptosis through the inhibition of Bad/Akt phosphorylation. trans-Vaccenic acid is a precursor for the synthesis of saturated fatty acid in the rumen and of conjugated Linoleic acid (CLA) at the tissue level. trans-Vaccenic acid exerts hypolipidemic effects in a rat model of obesity.
    trans-Vaccenic acid
  • HY-114202
    delta-Valerobetaine
    		≥98.0%
    delta-Valerobetaine is a precursor of trimethylamine N-oxide (TMAO).
    delta-Valerobetaine
  • HY-N2327
    Oleamide
    		99.96%
    Oleamide is an endogenous fatty acid amide which can be synthesized de novo in the mammalian nervous system, and has been detected in human plasma.
    Oleamide
  • HY-N0384
    Homovanillic acid
    		99.96%
    Homovanillic acid is a dopamine metabolite found to be associated with aromatic L-amino acid decarboxylase deficiency, celiac disease, growth hormone deficiency, and sepiapterin reductase deficiency.
    Homovanillic acid
  • HY-107608
    Leukotriene B4
    		≥98.0%
    Leukotriene B4 (LTB4) is known as one of the most potent chemoattractants and activators of leukocytes and is involved in inflammatory diseases. Leukotriene B4 is also an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs.
    Leukotriene B4
  • HY-P2293
    Luteinizing hormone (human)
    		≥98.0%
    Luteinizing hormone (human), a heterodimeric glycoprotein hormone produced by the pituitary gland (LH), plays key roles in human reproduction.
    Luteinizing hormone (human)
  • HY-B1342
    Vitamin A
    		99.27%
    Vitamin A (Vitamin A1) is an endogenous metabolite.
    Vitamin A
  • HY-113061
    Pseudouridine
    		99.88%
    Pseudouridine is an isomer of uridine and the most abundant modified nucleoside in non-coding RNA. It fine-tunes and stabilizes regional structures in rRNA and tRNA, maintaining their functions in mRNA decoding, ribosome assembly, processing, and translation. Pseudouridine-modified tRNA fragments can inhibit aberrant protein synthesis and hold promise for research on myelodysplastic syndrome (MDS)-related leukemia..
    Pseudouridine
  • HY-18252
    Avanafil
    		Modulator 98.66%
    Avanafil (TA-1790) is a potent and selective phosphodiesterase-5 (PDE-5) inhibitor with IC50 values of 5.2 nM, 630 nM, 5700 nM, 6200 nM, 12000 nM, 27000 nM, 51000 nM and 53000 nM for PDE-5, PDE-6, PDE-4, PDE-10, PDE-8, PDE-7, PDE-2 and PDE-1, respectively. Avanafil activates NO/cGMP/PKG signaling-pathway to decrease loss in BMD, bone atrophy, and oxidative stress. Avanafil inhibits cyclic guanosine monophosphate (cGMP) hydrolysis and thus increases cGMP levels. Avanafil can be used for the research of erectile dysfunction and osteoporosis.
    Avanafil
  • HY-W017162
    DL-3-Phenyllactic acid
    		99.91%
    DL-3-Phenyllactic acid is a broad-spectrum antimicrobial compound.
    DL-3-Phenyllactic acid
  • HY-B2123
    Lactose
    		≥98.0%
    Lactose is a β-galactoside consisting of galactose and glucose residues，the main carbohydrate in mammalian breast milk. Lactose，a macronutrient and an inducer of host innate immune responses，possesses immune modulatory functions.
    Lactose
  • HY-76542
    Vitamin D2
    		99.53%
    Vitamin D2 (Ergocalciferol), drived from plant sources or dietary supplements, could be used as supplement of Vitamin D.
    Vitamin D2
Cat. No. Product Name / Synonyms Application Reactivity