2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

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Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-W006057
    3-Methyl-2-oxobutanoic acid
    		99.10%
    3-Methyl-2-oxobutanoic acid is a precursor of pantothenic acid in Escherichia coli.
    3-Methyl-2-oxobutanoic acid
  • HY-N0057
    3,4-Dicaffeoylquinic acid
    		98.15%
    3,4-Dicaffeoylquinic acid (3,4-Di-O-caffeoylquinic acid), naturally isolated from Laggera alata, has antioxidative, DNA protective, neuroprotective and hepatoprotective properties. 3,4-Dicaffeoylquinic acid exerts apoptosis-mediated cytotoxicity and α-glucosidase inhibitory effects. 3,4-Dicaffeoylquinic acid possesses a unique mechanism of anti-influenza viral activity, that is, enhancing viral clearance by increasing TRAIL.
    3,4-Dicaffeoylquinic acid
  • HY-W018512
    7-Ketolithocholic acid
    		99.93%
    7-Ketolithocholic acid (3α-Hydroxy-7-oxo-5β-cholanic acid), a bile acid, can be absorbed and suppresses endogenous bile acid production and biliary cholesterol secretion.
    7-Ketolithocholic acid
  • HY-N0623S
    L-Tryptophan-d5
    		99.94%
    L-Tryptophan-d5 is the deuterium labeled L-Tryptophan. L-Tryptophan (Tryptophan) is an essential amino acid that is the precursor of serotonin, melatonin, and vitamin B3.
    L-Tryptophan-d<sub>5</sub>
  • HY-A0143
    Dihomo-γ-linolenic acid
    		≥99.0%
    Dihomo-γ-linolenic acid (DGLA) is a 20-carbon ω-6 fatty acid, with anti-inflammatory and anti-proliferative activities. Dihomo-γ-linolenic acid attenuates atherosclerosis in the apolipoprotein E deficient mouse model system.
    Dihomo-γ-linolenic acid
  • HY-N0058
    4,5-Dicaffeoylquinic acid
    		99.65%
    4,5-Dicaffeoylquinic acid (Isochlorogenic acid C) is an antioxidant, can be isolated from Gynura divaricata and Laggera alata. 4,5-Dicaffeoylquinic acid reduces islet cell apoptosis and improves pancreatic function in type 2 diabetic mice, and has obvious inhibitory activities against yeast α-glucosidase. 4,5-Dicaffeoylquinic acid inhibits prostate cancer cells through cell cycle arrest. 4,5-Dicaffeoylquinic acid also has anti-apoptotic, anti-injury and anti-hepatitis B virus effects.
    4,5-Dicaffeoylquinic acid
  • HY-111431A
    p-Cresyl sulfate potassium
    		99.92%
    p-Cresyl sulfate potassium is a uremic toxin that binds to a prototype protein. p-Cresyl sulfate potassium activates the JNK and p38 MAPK signaling pathways. p-Cresyl sulfate potassium has pro-inflammatory activity.
    p-Cresyl sulfate potassium
  • HY-128374
    D-Glucose 6-phosphate disodium salt
    		99.93%
    D-Glucose-6-phosphate disodium salt is a glucose sugar phosphorylated at the hydroxy group on carbon 6.
    D-Glucose 6-phosphate disodium salt
  • HY-113081
    1-Methyladenosine
    		99.21%
    1-Methyladenosine is an RNA modification that can serve as a tumor marker, with elevated levels in the body associated with cancer development. Following 1-methyladenosine methylation, upregulation of PPARδ expression regulates cholesterol metabolism and activates Hedgehog signaling pathway, driving liver tumorigenesis.
    1-Methyladenosine
  • HY-N0708
    Vanillic acid
    		99.75%
    Vanillic acid is a flavoring agent found in edible plants and fruits, also found in Angelica sinensis. Vanillic acid inhibits NF-κB activation. Anti-inflammatory, antibacterial, and chemopreventive effects.
    Vanillic acid
  • HY-107854
    N-Acetyl-5-hydroxytryptamine
    		99.96%
    N-Acetyl-5-hydroxytryptamine is a Melatonin precursor, and that it can potently activate TrkB receptor.
    N-Acetyl-5-hydroxytryptamine
  • HY-B0891
    17α-Hydroxyprogesterone
    		99.96%
    17α-Hydroxyprogesterone is a steroid hormone. 17α-Hydroxyprogesterone induces ovarian growth and yolk production in female crabs and increases blood pressure in sheep. 17α-Hydroxyprogesterone is mainly used in research related to crustacean reproduction and animal hypertension.
    17α-Hydroxyprogesterone
  • HY-100583
    (-)-(S)-Equol
    		99.71%
    (-)-(S)-Equol is a high affinity ligand for estrogen receptor β with a Ki of 0.73 nM.
    (-)-(S)-Equol
  • HY-B0739
    Citicoline
    		99.59%
    Citicoline is an endogenous intermediate in the synthesis of phosphatidylcholine which is a component of cell membranes. Citicoline inhibits reactive oxygen species (ROS) and apoptosis. Citicoline can be used for neurological disease and hearing loss study.
    Citicoline
  • HY-76082
    L-Pyroglutamic acid
    		99.61%
    L-Pyroglutamic acid is the levo-isomer of Pyroglutamic acid. L-Pyroglutamic acid is the biologically active enantiomer in humans. Pyroglutamic acid is an intermediate in glutathione metabolism. L-Pyroglutamic acid can be used as a biomarker for systemic lupus erythematosus (SLE).
    L-Pyroglutamic acid
  • HY-113128A
    sn-Glycerol 3-phosphate lithium
    		99.90%
    sn-Glycerol 3-phosphate lithium is an important intermediate in glycolysis and lipid metabolism. The cytosolic sn-Glycerol 3-phosphate dehydrogenase (GPDH) consumes NADH to generate sn-Glycerol 3-phosphate lithium from dihydroxyacetone phosphate (DHAP). Glyceroneogenesis is an important supplier of sn-Glycerol 3-phosphate lithium for lipid metabolism.
    sn-Glycerol 3-phosphate lithium
  • HY-N11287A
    UDP-xylose disodium
    		99.90%
    UDP-xylose disodium is an endogenous sugar nucleotide and a catalytic substrate of UDP-xylose disodium synthase (UXS). UDP-xylose disodium is a sugar donor for the synthesis of glycoproteins, polysaccharides, various metabolites and oligosaccharides in plants, vertebrates and fungi, and participates in the synthesis of proteoglycans as a glycosyl donor. UDP-xylose disodium participates in the regulation of the synthesis of extracellular matrix components and can be used to study the mechanism of proteoglycan biosynthesis in glycobiology and related diseases (such as connective tissue diseases)[1][2].
    UDP-xylose disodium
  • HY-P1240A
    Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat TFA
    		99.68%
    Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat (MOG (35-55)) TFA is a minor component of CNS myelin. Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat TFA has encephalitogenic activity and induces T cell proliferative. Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat TFA induces Th1 cytokine response as well as relatively high levels of IgG antibodies. Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat TFA produces a relapsing-remitting neurological disease with extensive plaque-like demyelination.
    Myelin Oligodendrocyte Glycoprotein Peptide (35-55), mouse, rat TFA
  • HY-113414
    Deoxycorticosterone
    		99.78%
    Deoxycorticosterone is a steroid hormone produced by the adrenal gland that possesses mineralocorticoid activity and acts as an aldosterone precursor. Deoxycorticosterone is an agonist for O. mykiss mineralocorticoid receptor (rtMR) transcription with EC50 of 0.16 nM. Deoxycorticosterone could acts as an immune stimulator in fish.
    Deoxycorticosterone
  • HY-111815A
    N4-Acetylcytidine triphosphate sodium
    		99.91%
    N4-Acetylcytidine triphosphate sodium is efficiently used as a substrate in T7 Polymerase-catalyzed in vitro transcription and it can be incorporated into multiple templates.
    N4-Acetylcytidine triphosphate sodium
Cat. No. Product Name / Synonyms Application Reactivity