2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

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Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N0570S1
    Hydroxytyrosol-d5
    Hydroxytyrosol-d5 is the deuterium labeled Hydroxytyrosol. Hydroxytyrosol (DOPET) is a phenolic compound drawn from the olive tree and its leaves with anti-oxidant, anti-atherogenic, anti-thrombotic, antimicrobial, anti-inflammatory and anti-tumour effects.
    Hydroxytyrosol-d<sub>5</sub>
  • HY-101047R
    D-erythro-Sphingosine (Standard)
    D-erythro-Sphingosine (Standard) is the analytical standard of D-erythro-Sphingosine. This product is intended for research and analytical applications. D-erythro-Sphingosine (Erythrosphingosine) is a very potent activator of p32-kinase with an EC50 of 8 μM, and inhibits protein kinase C (PKC). D-erythro-Sphingosine (Erythrosphingosine) is also a PP2A activator[1][2][3][4].
    D-erythro-Sphingosine (Standard)
  • HY-139576A
    Larsucosterol sodium
    Larsucosterol (DUR-928) sodium, a cholesterol metabolite, is a potent liver X receptor (LXR) antagonist. Larsucosterol sodium as a potent endogenous regulator decreases lipogenesis. Larsucosterol sodium inhibits the cholesterol biosynthesis via decreasing mRNA levels and inhibiting the activation of SREBP-1.
    Larsucosterol sodium
  • HY-113161R
    L-Octanoylcarnitine (Standard)
    L-Octanoylcarnitine (Standard) is the analytical standard of L-Octanoylcarnitine. This product is intended for research and analytical applications. L-Octanoylcarnitine is a plasma metabolite and a physiologically active form of octanoylcarnitine. L-Octanoylcarnitine can be used for the research of breast cancer.
    L-Octanoylcarnitine (Standard)
  • HY-N0339S
    Syringic acid-d6
    Syringic acid-d6 is the deuterium labeled Syringic acid. Syringic acid is correlated with high antioxidant activity and inhibition of LDL oxidation.
    Syringic acid-d<sub>6</sub>
  • HY-Y1097R
    Monomethyl phthalate (Standard)
    Monomethyl phthalate (Standard) is the analytical standard of Monomethyl phthalate. This product is intended for research and analytical applications. Monomethyl phthalate is a phthalate metabolite. Monomethyl phthalate acts as a urinary biomarker of phthalates exposure and can be used as a standard for the determination of thyroid cancer and benign nodule.
    Monomethyl phthalate (Standard)
  • HY-W014325R
    TRPM8 agonist WS-3 (Standard)
    TRPM8 agonist WS-3 (Standard) is the analytical standard of TRPM8 agonist WS-3. This product is intended for research and analytical applications. TRPM8 agonist WS-3 is an agonist of TRPM8 with an EC50 of 3.7 μM.
    TRPM8 agonist WS-3 (Standard)
  • HY-N0780R
    Isoalantolactone (Standard)
    Isoalantolactone (Standard) is the analytical standard of Isoalantolactone. This product is intended for research and analytical applications. Isoalantolactone is an apoptosis inducer, which also acts as an alkylating agent.
    Isoalantolactone (Standard)
  • HY-B0511S2
    Biotin-d2
    		98.53%
    Biotin-d2 is the deuterium labeled Biotin. Biotin is an enzyme co-factor present in minute amounts in every living cell.
    Biotin-d<sub>2</sub>
  • HY-138615S5
    Deoxythymidine-5'-triphosphate-d15 dilithium
    Deoxythymidine-5'-triphosphate-d15 (dTTP-d15) dilithium is the deuterium labeled Deoxythymidine-5'-triphosphate (HY-138615). Deoxythymidine-5'-triphosphate (dTTP) is one of the four nucleoside triphosphates. Deoxythymidine-5'-triphosphate (dTTP) is used in the synthesis of DNA.
    Deoxythymidine-5'-triphosphate-d<sub>15</sub> dilithium
  • HY-N0437S1
    Progesterone-13C5
    Progesterone-13C5 is the 13C-labeled Progesterone. Progesterone is a steroid hormone that regulates the menstrual cycle and is crucial for pregnancy.
    Progesterone-<sup>13</sup>C<sub>5</sub>
  • HY-W010178R
    4-Methyloctanoic acid (Standard)
    4-Methyloctanoic acid (Standard) is the analytical standard of 4-Methyloctanoic acid. This product is intended for research and analytical applications. 4-Methyloctanoic acid is a natural compound mainly responsible for the characteristic goaty sheepy flavour of sheep and goat milk[1].
    4-Methyloctanoic acid (Standard)
  • HY-N0698R
    Crocin II (Standard)
    Crocin II (Standard) is the analytical standard of Crocin II. This product is intended for research and analytical applications. Crocin II is isolated from the fruit of Gardenia jasminoides with antioxidant, anticancer, and antidepressant activity. Crocin II inhibits NO production with an IC50 value of 31.1 μM. Crocin II suppresses the expressions of protein and m-RNA of iNOS and COX-2.
    Crocin II (Standard)
  • HY-108568R
    15-Deoxy-Δ-12,14-prostaglandin J2 (Standard)
    15-Deoxy-Δ-12,14-prostaglandin J2 (Standard) is the analytical standard of 15-Deoxy-Δ-12,14-prostaglandin J2. This product is intended for research and analytical applications. 15-Deoxy-Δ-12,14-prostaglandin J2 (15d-PGJ2) is a cyclopentenone prostaglandin and a metabolite of PGD2. 15-Deoxy-Δ-12,14-prostaglandin J2 is a selective PPARγ (EC50 of 2 μM) and a covalent PPARδ agonist. 15-Deoxy-Δ-12,14-prostaglandin J2 promotes efficient differentiation of C3H10T1/2 fibroblasts to adipocytes with an EC50 of 7 μM.
    15-Deoxy-Δ-12,14-prostaglandin J2 (Standard)
  • HY-18258S
    Berberine-d6 chloride
    Berberine-d6 (chloride) is the deuterium labeled Berberine chloride. Berberine chloride is an alkaloid that acts as an antibiotic. Berberine chloride induces reactive oxygen species (ROS) generation and inhibits DNA topoisomerase. Antineoplastic properties.
    Berberine-d<sub>6</sub> chloride
  • HY-B1659S2
    Glycerol-13C-1 (90% in water)
    		99.3%
    Glycerol-13C-1 (90% in water) is the 13C labeled Glycerol. Glycerol is used in sample preparation and gel formation for polyacrylamide gel electrophoresis.
    Glycerol-<sup>13</sup>C-1 (90% in water)
  • HY-10572S1
    Efavirenz-13C6
    Efavirenz-13C6 is the 13C-labeled Efavirenz. Efavirenz (DMP 266) is a potent inhibitor of the wild-type HIV-1 reverse transcriptase with a Ki of 2.93 nM and exhibits an IC95 of 1.5 nM for the inhibition of HIV-1 replicative spread in cell culture.
    Efavirenz-<sup>13</sup>C<sub>6</sub>
  • HY-113137R
    N2,N2-Dimethylguanosine (Standard)
    N2,N2-Dimethylguanosine (Standard) is the analytical standard of N2,N2-Dimethylguanosine. This product is intended for research and analytical applications. N2,N2-Dimethylguanosine is an urinary nucleoside, a primary degradation product of tRNA.
    N2,N2-Dimethylguanosine (Standard)
  • HY-N0629R
    Maslinic acid (Standard)
    Maslinic acid (Standard) is the analytical standard of Maslinic acid. This product is intended for research and analytical applications. Maslinic acid can inhibit the DNA-binding activity of NF-κB p65 and abolish the phosphorylation of IκB-α, which is required for p65 activation.
    Maslinic acid (Standard)
  • HY-N2907R
    Atranorin (Standard)
    Atranorin (Standard) is the analytical standard of Atranorin (HY-N2907). This product is intended for research and analytical applications. Atranorin is a secondary metabolite of lichens and AKT inhibitor. Atranorin possesses multiple activities such as antibacterial, anti-inflammatory, antioxidant, anti-glycation, analgesic, and anti-tumor effects. Atranorin has IC50 values for scavenging DPPH and ABTS free radicals of 117 μM and less than 10 μM, respectively. Additionally, Atranorin also exhibits effects in promoting wound healing. Atranorin can be used in the research of various diseases, including myelodysplastic syndromes, tumors, and inflammatory conditions.
    Atranorin (Standard)
Cat. No. Product Name / Synonyms Application Reactivity