2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Endogenous Metabolite

Endogenous Metabolite

Endogenous Metabolite

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Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N2454R
    β-Elemonic acid (Standard)
    β-Elemonic acid (Standard) is the analytical standard of β-Elemonic acid. This product is intended for research and analytical applications. β-Elemonic acid is a triterpene isolated from Boswellia carterii. β-Elemonic acid induces cell apoptosis, reactive oxygen species (ROS) and COX-2 expression and inhibits prolyl endopeptidase. β-Elemonic acid exhibits anticancer and anti-inflammatory effects.
    β-Elemonic acid (Standard)
  • HY-W018772S1
    D-Ribose-13C
    D-Ribose-13C is the 13C labeled D-Ribose. D-Ribose is an energy enhancer, and acts as a sugar moiety of ATP, and widely used as a metabolic therapy supplement for chronic fatigue syndrome or cardiac energy metabolism. D-Ribose is active in protein glycati
    D-Ribose-<sup>13</sup>C
  • HY-W032915R
    5-Phenylvaleric acid (Standard)
    5-Phenylvaleric acid (Standard) is an analytical standard for 5-Phenylvaleric acid (HY-W032915). This product is used for research and analytical applications. 5-Phenylvaleric acid (5-Phenylpentanoic acid) is a major metabolite produced by the gut microbiota during the metabolism of flavan-3-ols and can serve as a biomarker for flavan-3-ol intake. 5-Phenylvaleric acid can also be used as a raw material for the synthesis of polyhydroxyalkanoates.
    5-Phenylvaleric acid (Standard)
  • HY-B1449S3
    Uridine-13C-2
    Uridine-13C-2 is the 13C labeled Uridine.
    Uridine-<sup>13</sup>C-2
  • HY-W015913S4
    2-Oxopropanoate-13C5 sodium
    2-Oxopropanoate-13C5 (sodium) is the 13C labeled Sodium 2-oxopropanoate. Sodium 2-oxopropanoate (Sodium pyruvate), a three-carbon metabolite of Glucose, is a compound produced in the glycolytic pathway. Sodium 2-oxopropanoate is a free radical scavenger that can scavenge ROS.
    2-Oxopropanoate-<sup>13</sup>C<sub>5</sub> sodium
  • HY-B0412S3
    Estriol-13C3
    Estriol-13C3 is the 13C-labeled Estriol. Estriol is an antagonist of the G-protein coupled estrogen receptor in estrogen receptor-negative breast cancer cells.
    Estriol-<sup>13</sup>C<sub>3</sub>
  • HY-10572BR
    (Rac)-Efavirenz (Standard)
    (Rac)-Efavirenz (Standard) is the analytical standard of (Rac)-Efavirenz. This product is intended for research and analytical applications. (Rac)-Efavirenz is the isomer of Efavirenz (HY-10572). Efavirenz (DMP 266) is a potent inhibitor of the wild-type HIV-1 reverse transcriptase with a Ki of 2.93 nM and exhibits an IC95 of 1.5 nM for the inhibition of HIV-1 replicative spread in cell culture.
    (Rac)-Efavirenz (Standard)
  • HY-W015924R
    2-Hydroxyisobutyric acid (Standard)
    2-Hydroxyisobutyric acid (Standard) is the analytical standard of 2-Hydroxyisobutyric acid. This product is intended for research and analytical applications. 2-Hydroxyisobutyric acid (2-HIBA) is a selective modulator of the Insulin/IGF-1 pathway and the p38 MAPK pathway, which reduces reactive oxygen species (ROS) and fat accumulation in Caenorhabditis elegans. 2-Hydroxyisobutyric acid promotes β-oxidation and inhibits fatty acid synthesis by upregulating SKN-1/NRF2 and downregulating SREBP-1c transcription factors. 2-Hydroxyisobutyric acid has anti-aging and lipid-lowering effects, and can be used to study metabolic diseases such as obesity and diabetes. 2-Hydroxyisobutyric acid is also a renewable precursor of methacrylate through 2-HIB-CoA mutase-mediated biosynthesis[1][2].
    2-Hydroxyisobutyric acid (Standard)
  • HY-N0378S3
    D-Mannitol-2-13C
    		99.95%
    D-Mannitol-2-13C is the 13C labeled D-Mannitol.
    D-Mannitol-2-<sup>13</sup>C
  • HY-N6623R
    Malvidin-3-galactoside chloride (Standard)
    Malvidin-3-galactoside (chloride) (Standard) is the analytical standard of Malvidin-3-galactoside (chloride). This product is intended for research and analytical applications. Malvidin-3-galactoside chloride, an anthocyanin monomer, induces hepatocellular carcinoma (HCC) cells cycle arrest and apoptosis. Malvidin-3-galactoside chloride inhibits the production and accumulation of ROS. Malvidin-3-galactoside chloride has anti-tumor function.
    Malvidin-3-galactoside chloride (Standard)
  • HY-108695BR
    (±)-Enterodiol (Standard)
    (±)-Enterodiol (Standard) is the analytical standard of (±)-Enterodiol. This product is intended for research and analytical applications. (±)-Enterodiol is the racemate of Enterodiol (HY-108695). Enterodiol is transformed by human intestinal bacteria from lignans contained in various whole-grain cereals, nuts, legumes, flaxseed, and vegetables. Enterodiol has an apoptotic effect in colorectal cancer (CRC) cells. Enterodiol has anti-cancer activities.
    (±)-Enterodiol (Standard)
  • HY-N0538S
    Xylitol-1-13C
    		≥99.0%
    Xylitol-1-13C is the 13C labeled Xylit.
    Xylitol-1-<sup>13</sup>C
  • HY-116514R
    (S)-(?)-Perillyl alcohol (Standard)
    (S)-(?)-Perillyl alcohol (Standard) is the analytical standard of (S)-(?)-Perillyl alcohol. This product is intended for research and analytical applications. (S)-(?)-Perillyl alcohol is a monoterpene found in lavender, inhibits farnesylation of Ras, upregulates the mannose-6-phosphate receptor and induces apoptosis. Anti-cancer activity.
    (S)-(?)-Perillyl alcohol (Standard)
  • HY-N0036R
    Costunolide (Standard)
    Costunolide (Standard) is the analytical standard of Costunolide. This product is intended for research and analytical applications. Costunolide ((+)-Costunolide) is a naturally occurring sesquiterpene lactone, with antioxidative, anti-inflammatory, antiallergic, bone remodeling, neuroprotective, hair growth promoting, anticancer, and antidiabetic properties. Costunolide can induce cell cycle arrest and apoptosis on breast cancer cells.
    Costunolide (Standard)
  • HY-17563S3
    2'-Deoxyguanosine-d13
    		99.9%
    2'-Deoxyguanosine-d13 (Deoxyguanosine-d13; Guanine deoxyriboside-d13) is deuterium labeled 2'-Deoxyguanosine (HY-17563). 2'-Deoxyguanosine (Deoxyguanosine) is deoxyguanosine.
    2'-Deoxyguanosine-d<sub>13</sub>
  • HY-W008449S1
    1-Methylxanthine-13C4,15N3
    1-Methylxanthine-13C4,15N3 is the 13C-labeled and 15N-labeled 1-Methylxanthine. 1-Methylxanthine, a caffeine derivative, is an essential human urinary metabolite of caffeine and theophylline (1,3-dimethylxanthine, TP). 1-Methylxanthine enhances the radiosensitivity of tumor cells.
    1-Methylxanthine-<sup>13</sup>C<sub>4</sub>,<sup>15</sup>N<sub>3</sub>
  • HY-N0570S1
    Hydroxytyrosol-d5
    Hydroxytyrosol-d5 is the deuterium labeled Hydroxytyrosol. Hydroxytyrosol (DOPET) is a phenolic compound drawn from the olive tree and its leaves with anti-oxidant, anti-atherogenic, anti-thrombotic, antimicrobial, anti-inflammatory and anti-tumour effects.
    Hydroxytyrosol-d<sub>5</sub>
  • HY-101047R
    D-erythro-Sphingosine (Standard)
    D-erythro-Sphingosine (Standard) is the analytical standard of D-erythro-Sphingosine. This product is intended for research and analytical applications. D-erythro-Sphingosine (Erythrosphingosine) is a very potent activator of p32-kinase with an EC50 of 8 μM, and inhibits protein kinase C (PKC). D-erythro-Sphingosine (Erythrosphingosine) is also a PP2A activator[1][2][3][4].
    D-erythro-Sphingosine (Standard)
  • HY-139576A
    Larsucosterol sodium
    Larsucosterol (DUR-928) sodium, a cholesterol metabolite, is a potent liver X receptor (LXR) antagonist. Larsucosterol sodium as a potent endogenous regulator decreases lipogenesis. Larsucosterol sodium inhibits the cholesterol biosynthesis via decreasing mRNA levels and inhibiting the activation of SREBP-1.
    Larsucosterol sodium
  • HY-113161R
    L-Octanoylcarnitine (Standard)
    L-Octanoylcarnitine (Standard) is the analytical standard of L-Octanoylcarnitine. This product is intended for research and analytical applications. L-Octanoylcarnitine is a plasma metabolite and a physiologically active form of octanoylcarnitine. L-Octanoylcarnitine can be used for the research of breast cancer.
    L-Octanoylcarnitine (Standard)
Cat. No. Product Name / Synonyms Application Reactivity