1. Signaling Pathways
  2. Metabolic Enzyme/Protease
  3. Endogenous Metabolite

Endogenous Metabolite

Metabolite results when a drug is metabolized into a modified form which continues to produce effects. A metabolome in a given body fluid is influenced by endogenous factors such as age, sex, body composition and genetics as well as underlying pathologies.The levels of the enormous array of unique small-molecule metabolites are usually kept tightly regulated by the activity of a very large array of enzymes and transporters responsible for the production, transformation, degradation, and compartmentalization of these small molecules.The levels of the endogenous small molecules present in the brain are normally tightly regulated.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-116865
    Equilenin
    ≥98.0%
    Equilenin is a B-ring unsaturated estrogen and one of the main ingredients in Premarin, a drug commonly used in estrogen replacement therapy. Equilenin can bind to estrogen receptors in the body and exert effects similar to endogenous estrogen. Equilenin can be used in estrogen replacement therapy and breast cancer research.
    Equilenin
  • HY-W017389S1
    Xanthine-15N2
    99.35%
    Xanthine-15N2 is a 15N-labeled Xanthine (HY-W017389). Xanthine, a plant alkaloid found in tea, coffee, and cocoa, is a mild stimulant of the central nervous system. Xanthine also acts as an intermediate product on the pathway of purine degradation.
    Xanthine-<sup>15</sup>N<sub>2</sub>
  • HY-150773S1
    Guanosine triphosphate-d14 dilithium
    Guanosine triphosphate-d14 (GTP-d14) dilithium is a deuterium labeled Guanosine triphosphate (HY-113225). Guanosine triphosphate is a native nucleotide. The derivatives of GTP may be used as specific inhibitors against COVID-19.
    Guanosine triphosphate-d<sub>14</sub> dilithium
  • HY-100582S
    Ribitol-1-13C
    99.51%
    Ribitol-1-13C is the 13C labeled Ribitol. Ribitol is a crystalline pentose alcohol formed by the reduction of ribose. Enhancing the flux of D-glucose to the pentose phosphate pathway in Saccharomyces cerevisiae for the production of D-ribose and ribitol.
    Ribitol-1-<sup>13</sup>C
  • HY-113208
    13,14-Dihydro-15-keto Prostaglandin F2α
    ≥99.0%
    13,14-Dihydro-15-keto Prostaglandin F2α (13,14-Dihydro-15-keto-PGF2α) is an endogenous metabolite present in Blood that can be used for the research of Pregnancy.
    13,14-Dihydro-15-keto Prostaglandin F2α
  • HY-W105731
    1,10-Diiododecane
    99.66%
    1,10-Diiododecane (Decamethylene diiodide) serves as a crosslinking reagent for tetrabutylammonium polygalacturonic acid and acts as an alkylating agent in the synthesis of both symmetrical and unsymmetrical bis-cryptophanes, in addition to being utilized for the production of decane at a temperature of 20°C.
    1,10-Diiododecane
  • HY-W060074
    1-Acetyl-β-carboline
    1-Acetyl-β-carboline is a metabolite of Streptomyces kasugaensis and antibacterial agent. 1-Acetyl-β-carboline increases tyrosinase activity, reduces ERK phosphorylation. 1-Acetyl-β-carboline exhibits antibacterial activity against methicillin-resistant Staphylococcus aureus (MRSA) strains with MICs ranging from 128 to 256 ug/mL. 1-Acetyl-β-carboline increases the melanin.
    1-Acetyl-β-carboline
  • HY-113081S
    1-Methyladenosine-d3
    1-Methyl Adenosine-d3 is the deuterium labeled 1-Methyladenosine. 1-Methyladenosine is an RNA modification that can serve as a tumor marker, with elevated levels in the body associated with cancer development. Following 1-methyladenosine methylation, upregulation of PPARδ expression regulates cholesterol metabolism and activates Hedgehog signaling pathway, driving liver tumorigenesis.
    1-Methyladenosine-d<sub>3</sub>
  • HY-W015882R
    4-Methylpentanoic acid (Standard)
    4-Methylpentanoic acid (Isocaproic acid) (Standard) is an analytical standard form of 4-Methylpentanoic acid (HY-W015882). This product is intended for research and analytical applications. 4-Methylpentanoic acid (Isocaproic Acid) is a short-chain fatty acid, an endogenous metabolite, and a metabolite of 20 α-hydroxycholesterol (HY-12316), which can be found in feces. The concentration of 4-Methylpentanoic acid is closely related to some diseases, such as depression. 4-Methylpentanoic acid can also be used in the research of cholesterol metabolism.
    4-Methylpentanoic acid (Standard)
  • HY-B1744S
    Pyridoxal phosphate-d5
    99.30%
    Pyridoxal phosphate-d5 is the deuterium labeled Pyridoxal phosphate. Pyridoxal phosphate is the active form of vitamin B6, acts as an inhibitor of reverse transcriptases, and is used for the treatment of tardive dyskinesia.
    Pyridoxal phosphate-d<sub>5</sub>
  • HY-A0070R
    Liothyronine sodium (Standard)
    Liothyronine (sodium) (Standard) is the analytical standard of Liothyronine (sodium). This product is intended for research and analytical applications. Liothyronine sodium is an active form of thyroid hormone. Liothyronine sodium is a potent thyroid hormone receptors TRα and TRβ agonist with Kis of 2.33 nM for hTRα and hTRβ, respectively.
    Liothyronine sodium (Standard)
  • HY-128736
    L-2-Phosphoglyceric acid
    L-2-Phosphoglyceric acid is an endogenous metabolite.
    L-2-Phosphoglyceric acid
  • HY-125818S1
    Cytidine-5′-triphosphate-d14 disodium
    98.00%
    Cytidine-5′-triphosphate-d14 disodium is the deuterium labeled Cytidine-5'-triphosphate. Cytidine 5′-triphosphate (Cytidine triphosphate;5'-CTP) is a nucleoside triphosphate and serves as a building block for nucleotides and nucleic acids, lipid biosynthesis. Cytidine triphosphate synthase can catalyze the formation of cytidine 5′-triphosphate from uridine 5′-triphosphate (UTP). Cytidine 5′-triphosphate is an essential biomolecule in the de novo pyrimidine biosynthetic pathway in T. gondii.
    Cytidine-5′-triphosphate-d<sub>14</sub> disodium
  • HY-113026S
    (2RS,4R,8R)-δ-Tocopherol-d4 (Mixture of Diastereomers)
    99.54%
    (2RS,4R,8R)-δ-Tocopherol-d4 (Mixture of Diastereomers) is the deuterium labeled (2RS,4R,8R)-δ-Tocopherol (Mixture of Diastereomers).
    (2RS,4R,8R)-δ-Tocopherol-d<sub>4</sub> (Mixture of Diastereomers)
  • HY-113061R
    Pseudouridine (Standard)
    Pseudouridine (Standard) is the analytical standard of Pseudouridine. This product is intended for research and analytical applications. Pseudouridine is an isomer of the nucleoside uridine, and the most abundant modified nucleoside in non-coding RNAs. Pseudouridine in rRNA and tRNA can fine-tune and stabilize the regional structure and help maintain their functions in mRNA decoding, ribosome assembly, processing and translation[4].
    Pseudouridine (Standard)
  • HY-W336192
    (3E,8Z,11Z)-3,8,11-Tetradecatrienyl acetate
    (3E,8Z,11Z)-3,8,11-Tetradecatrienyl acetate is a sex pheromone capable of attracting male South American tomato pinworms (Scrobipalpuloides absoluta), which can be isolated from the tomato pest.
    (3E,8Z,11Z)-3,8,11-Tetradecatrienyl acetate
  • HY-41314
    Ethyl 3-methyl-2-butenoate
    99.54%
    Ethyl 3-methyl-2-butenoate is a volatile compound that can be isolated from sea buckthorn.
    Ethyl 3-methyl-2-butenoate
  • HY-114293S
    Acetyl coenzyme A-13C2 lithium
    Acetyl coenzyme A-13C2 lithium is the 13C-labeled Acetyl coenzyme A (HY-114293). Radioactive isotopes labeled compounds can be used in metabolic analysis, allowing the movement of individual atoms to be precisely tracked and quantified.
    Acetyl coenzyme A-<sup>13</sup>C<sub>2</sub> lithium
  • HY-100583R
    (-)-(S)-Equol (Standard)
    (-)-(S)-Equol (Standard) is the analytical standard of (-)-(S)-Equol. This product is intended for research and analytical applications. (-)-(S)-Equol is a high affinity ligand for estrogen receptor β with a Ki of 0.73 nM.
    (-)-(S)-Equol (Standard)
  • HY-N0537S3
    Xylose-2-13C
    99.89%
    Xylose-2-13C (D-(+)-Xylose-2-13C) is the 13C labeled Xylose (HY-N0537). Xylose (D-(+)-Xylose) is a natural pentose sugar that is catalyzed by xylose isomerase to form xylulose, which is a key step in the anaerobic ethanol fermentation of Xylose. Xylose can be used by microorganisms to produce fuels, chemicals, and bulk industrial enzymes. Xylose provides the substances and energy for cells, as a carbon source for the biosynthesis of high-value chemicals and biofuel. Xylose can be used to fully explore lignocellulose resources and provide a new direction for microbia fermentation.
    Xylose-2-<sup>13</sup>C
Cat. No. Product Name / Synonyms Application Reactivity