2. Signaling Pathways
  3. Anti-infection
  4. Fungal

Fungal

Fungal

Related Products

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An antifungal agent is a drug that selectively eliminates fungal pathogens from a host with minimal toxicity to the host.

Classes: 1. Polyene Antifungal Drugs: Amphotericin, nystatin, and pimaricin interact with sterols in the cell membrane (ergosterol in fungi, cholesterol in humans) to form channels through which small molecules leak from the inside of the fungal cell to the outside. 2. Azole Antifungal Drugs: Fluconazole, itraconazole, and ketoconazole inhibit cytochrome P450-dependent enzymes (particularly C14-demethylase) involved in the biosynthesis of ergosterol, which is required for fungal cell membrane structure and function. 3. Allylamine and Morpholine Antifungal Drugs: lylamines (naftifine, terbinafine) inhibit ergosterol biosynthesis at the level of squalene epoxidase. The morpholine drug, amorolfine, inhibits the same pathway at a later step. 4. Antimetabolite Antifungal Drugs: 5-Fluorocytosine acts as an inhibitor of both DNA and RNA synthesis via the intracytoplasmic conversion of 5-fluorocytosine to 5-fluorouracil.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N14123
    Cladosporide C
    		Inhibitor
    Cladosporide C is found in the strain of Cladosporium sp. IFM 49190. Cladosporide C has no antifungal activity.
    Cladosporide C
  • HY-N3089
    Phaseollidin
    		Inhibitor
    Phaseollidin is an antifungal agent that can be isolated from Phaseolus vulgaris L..
    Phaseollidin
  • HY-N14554
    Dihydroniphimycin
    		Inhibitor
    Dihydroniphimycin has anti-fungal, yeast and Gram-positive bacteria action.
    Dihydroniphimycin
  • HY-116060
    RK-286D
    		Inhibitor
    RK-286D is an antibiotic and a PKC inhibitor with antimicrobial activity. RK-286D shows inhibitory activities against bleb formation induced by PDBu (HY-18985) and in vitro PKC activity.
    RK-286D
  • HY-N0673R
    Pseudolaric Acid A (Standard)
    		Inhibitor
    Pseudolaric Acid A (Standard) is the analytical standard of Pseudolaric Acid A. This product is intended for research and analytical applications. Pseudolaric Acid A is a diterpene acid isolated from Pseudolarix kaempferi, has antifungal, cytotoxic and antifertile activities.
    Pseudolaric Acid A (Standard)
  • HY-P5587
    Dermaseptin-S5
    		Inhibitor
    Dermaseptin-S5 is an antimicrobial peptide derived from frog skin against filamentous fungi.
    Dermaseptin-S5
  • HY-B1360R
    Chlorquinaldol (Standard)
    		Inhibitor
    Chlorquinaldol (Standard) is the analytical standard of Chlorquinaldol. This product is intended for research and analytical applications. Chlorquinaldol (Chloquinan) is an antibacterial agent with the potential use in topical skin conditions and vaginal infections. Chlorquinaldol is a β-catenin/TCF4 inhibitor, showing anti-proliferation, anti-migration, and apoptosis-inducing activity in cancer cells.
    Chlorquinaldol (Standard)
  • HY-B0101A
    Fluconazole hydrate
    		Inhibitor
    Fluconazole (hydrate) is a triazole antifungal drug used in the treatment and prevention of superficial and systemic fungal infections.
    Fluconazole hydrate
  • HY-N0444R
    Rubiadin (Standard)
    		Inhibitor
    Rubiadin (Standard) is the analytical standard of Rubiadin. This product is intended for research and analytical applications. Rubiadin is a dihydroxy anthraquinone isolated from Rubia cordifolia. Rubiadin has a potent antixidant activity.
    Rubiadin (Standard)
  • HY-N1300
    Shizukanolide F
    		Inhibitor
    Shizukanolide F is a dimeric sesquiterpene, which is derivated from Chloranthus japonicus Sieb. Shizukanolide F exhibits potent antifungal activities against various plant pathogenic fungi and anti-metastasis breast cancer.
    Shizukanolide F
  • HY-N14666
    Agrocybin
    		Inhibitor
    Agrocybin is an antifungal peptide that exerts antifungal activity against several fungal species but lacks inhibitory activity against bacteria. Agrocybin attenuates the activity of HIV-1 reverse transcriptase.
    Agrocybin
  • HY-W762060
    Metiram
    Metiram is a polymeric dithiocarbamate pesticide active as a fungicide. Metiram is widely used to protect crops such as tomatoes, potatoes, apples, grapevines, etc. Human and environmental exposure from the representative use of Metiram on potatoes is considered non-negligible. Metiram is considered necessary in the control of serious threats to plant health that cannot be suppressed by other available means, including non-chemical methods.
    Metiram
  • HY-162615
    Antibacterial agent 225
    		Inhibitor
    Antibacterial agent 225 (compound 12a-2) simultaneously exerts excellent bifunctional effects of fungal inhibition and immune activation.
    Antibacterial agent 225
  • HY-B0301R
    Bifonazole (Standard)
    		Inhibitor
    Bifonazole (Standard) is the analytical standard of Bifonazole. This product is intended for research and analytical applications. Bifonazole (Bay H-4502) is an imidazole antifungal agent.
    Bifonazole (Standard)
  • HY-W320538
    Benz[g]isoquinoline-5,10-dione
    		Inhibitor
    Benz[g]isoquinoline-5,10-dione, an active component isolated from the ethanolic extract of the aerial parts of Mitracarpus scaber, demonstrates notable in vitro inhibitory activity against AIDS-related pathogens, along with significant antibacterial and antifungal properties, as evidenced by the agar well-diffusion assay.
    Benz[g]isoquinoline-5,10-dione
  • HY-121214
    Amisulbrom
    		Inhibitor 99.92%
    Amisulbrom is a sulfonamide fungicide used to control oomycete diseases. Amisulbrom inhibits the cytochrome-bc1 complex of the mitochondrial electron transport system[1].
    Amisulbrom
  • HY-N14195
    Mathemycin A
    		Inhibitor
    Mathemycin A has an inhibitory effect on pathogenic fungi. Mathemycin A inhibits the Phytophthora infestans JO8 in vitro (MIC is 7.8 μg/mL), and it inhibits JO8 in greenhouse (LD50 is 42 X 10-6, LC90 is 500 X 10-6).
    Mathemycin A
  • HY-N14248
    Melithiazole A
    		Inhibitor
    Melithiazol A is an antibiotic. Melithiazole A is a β-methoxyacrylate (MOA) inhibitor with strong anti-agent activity. Antifungal and cytotoxic agent.
    Melithiazole A
  • HY-17395R
    Terbinafine hydrochloride (Standard)
    		Inhibitor
    Terbinafine hydrochloride (Standard) is the analytical standard of Terbinafine hydrochloride. This product is intended for research and analytical applications. Terbinafine hydrochloride (TDT 067 hydrochloride) is an orally active and potent antifungal agent. Terbinafine hydrochloride is a potent non-competitive inhibitor of squalene epoxidase from Candida, with a Ki of 30 nM. Terbinafine hydrochloride also shows antibacterial activity against certain Gram-positive and Gram-negative bacteria. Terbinafine hydrochloride is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Terbinafine hydrochloride (Standard)
  • HY-N13999
    Clavamycin D
    		Inhibitor
    Clavamycin D has strong anti-candida activity, and its action can be antagonized by dipeptide or tripeptide, but amino acid can not cancel its action. No antibacterial activity and no inhibition of β-lactamase.
    Clavamycin D
Cat. No. Product Name / Synonyms Application Reactivity