1. Signaling Pathways
  2. Anti-infection
  3. Bacterial

Bacterial

Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-131165R
    Amoxicillin trihydrate mixture with potassium clavulanate (4:1) (Standard)
    Inhibitor
    Amoxicillin (trihydrate) mixture with potassium clavulanate (4:1) (Standard) is the analytical standard of Amoxicillin (trihydrate) mixture with potassium clavulanate (4:1). This product is intended for research and analytical applications. Amoxicillin (trihydrate) mixture with potassium clavulanate (4:1) an antibiotic with good oral absorption and broad spectrum antimicrobial activity. Amoxicillin (trihydrate) mixture with potassium clavulanate (4:1) inhibits the biosynthesis of polypeptides in the cell wall, thereby inhibiting cell growth.
    Amoxicillin trihydrate mixture with potassium clavulanate (4:1) (Standard)
  • HY-59097
    (E/Z)-Tapinarof
    Inhibitor
    (E/Z)-Tapinarof ((E/Z)-WBI-1001; 3,5-dihydroxy-4-isopropylstilbene) is a broad-spectrum antibiotic. (E/Z)-Tapinarof has anti-bacterial, anti-fungal and anti-nematode activities.
    (E/Z)-Tapinarof
  • HY-N14832
    Griseorhodin G
    Inhibitor
    Griseorhodin G is a quinone antibiotic. Griseorhodin G has antitumor activity.
    Griseorhodin G
  • HY-N14276
    Miyakamide B1
    Inhibitor
    Miyakamide B1 is an antibiotic with insecticidal effect. Miyakamide B1 inhibits the growth of Artemia salina. Miyakamide B1 has a weak antixanthomonas activity. Miyakamide B1 inhibits P388 cells with an IC50 of 8.8 μg/mL.
    Miyakamide B1
  • HY-157130
    T3SS-IN-3
    Inhibitor
    T3SS-IN-3 (compound F-24) is an inhibitor of type III secretion system (T3SS). T3SS-IN-3 inhibits the transcription of hrpY gene significantly without inhibiting bacterial growth.
    T3SS-IN-3
  • HY-127019R
    Nigericin (Standard)
    Inhibitor
    Nigericin (Standard) is the analytical standard of Nigericin (HY-127019). This product is intended for research and analytical applications. Nigericin is an antibiotic derived from Streptomyces hygroscopicus that act as a K+/H+ ionophore, promoting K+/H+ exchange across mitochondrial membranes. Nigericin is a NLRP3 activator. Nigericin shows promising anti-cancer activities through decreasing intracellular pH (pHi), and inactivation of Wnt/β-catenin signals. Nigericin induces pyroptosis through caspase 1/GSDMD in TNBC.
    Nigericin (Standard)
  • HY-119480R
    Megazol (Standard)
    Inhibitor
    Megazol (Standard) is the analytical standard of Megazol. This product is intended for research and analytical applications. Megazol is an orally active antibacterial agent. Megazol has effective inhibitory against T. b. brueei with an EC50 of 0.01 μg/mL. Megazol can be used for the research of protozoan infections.
    Megazol (Standard)
  • HY-B1414R
    Chloroxylenol (Standard)
    Inhibitor
    Chloroxylenol (Standard) is the analytical standard of Chloroxylenol. This product is intended for research and analytical applications. Chloroxylenol is a broad-spectrum antibacterial agent that can be used to control bacteria, algae, fungi and viruses.
    Chloroxylenol (Standard)
  • HY-123216
    Cefmatilen
    Inhibitor
    Cefmatilen (S-1090) is an orally-active cephalosporin antibiotic that shows high activity against a variety of Gram-positive and Gram-negative bacteria, including Streptococcus pyogenes and Neisseria gonorrhoeae.
    Cefmatilen
  • HY-N14088
    Chrysospermin A
    Inhibitor
    Chrysospermin A has antibacterial activities against individual Gram-positive bacteria (Staphylococcus aureus, Bacillus subtilis), Klebsiella pneumoniae and individual yeasts (Ocher echinoderma, saccharomyces cerevisiae).
    Chrysospermin A
  • HY-136954
    LL-BM123γ2
    Inhibitor
    LL-BM123γ2 is an antibacterial agent which is active against a variety of microorganisms. LL-BM123γ2 can be used for antibacterial research.
    LL-BM123γ2
  • HY-N14106
    Cinerubin R
    Inhibitor
    Cinerubin R has anti-Gram-positive bacteria and inhibition of tumor cell activity, and its inhibition effect on multidrug resistant (MDR) cells is the same as that on protocells.
    Cinerubin R
  • HY-161988
    Antimicrobial agent-34
    Inhibitor
    Antimicrobial agent-34 (compound 4h) is an antibacterial agent (MIC = 1–4 μg/mL), with a clogP value of 9.14. Antimicrobial agent-34 has good plasma stability (HC50 of 131.1 μg/mL) and good membrane selectivity (HC50/MIC is 65.6), with rapid sterilization capability. Antimicrobial agent-34 destroys the integrity of bacterial cell membranes, induces an increase in intracellular reactive oxygen species, and leaks protein and DNA, ultimately leading to bacterial death. Antimicrobial agent-34 demonstrates significant in vivo antibacterial potency in a mouse sepsis model infected with Staphylococcus aureus ATCC43300.
    Antimicrobial agent-34
  • HY-N14787
    Basidalin
    Inhibitor
    Basidalin has the ability of anti-Gram-positive bacteria, negative bacteria and inhibition of mouse leukemia L-1210 cell.
    Basidalin
  • HY-W740028
    Cefditoren-d3 sodium
    Inhibitor
    Cefditoren-d3 (sodium) (ME 1206-d3) is deuterium labeled Cefditoren (sodium). Cefditoren sodium (ME 1206) is a broad-spectrum, third-generation, oral cephalosporin antibacterial with enhanced stability against many common β lactamases. Cefditoren sodium has activity against Gram-negative organisms and Gram-positive organisms. Cefditoren sodium can be used in the research of infection diseases such as acute exacerbations of chronic bronchitis, community-acquired pneumonia (CAP), streptococcal pharyngitis/tonsillitis, or uncomplicated skin and skin structure infections.
    Cefditoren-d<sub>3</sub> sodium
  • HY-163142
    Antibacterial agent 172
    Inhibitor
    Antibacterial agent 172 (Compound 6a) is a <,i>Clostridioides difficile (Cd) SpoVD inhibitor (IC50=89 nM) that effectively inhibits sporulation of Clostridioides difficile. Antibacterial agent 172 can be used in the study of bacterial infections.
    Antibacterial agent 172
  • HY-105717
    Meralein sodium
    Inhibitor
    Meralein sodium is an antiseptic agent.
    Meralein sodium
  • HY-170970
    Mtb-IN-10
    Inhibitor
    Mtb-IN-10 (Compound P15) is a Rv1625c/Cya activator that regulates cAMP metabolism to influence the growth of Mycobacterium tuberculosis (Mtb). Mtb-IN-10 exhibits an EC50 of 1.96 µM in an Mtb-infected macrophage model and demonstrates 58.0% oral bioavailability in mice at a 20 mg/kg dose. It may regulate intracellular signaling and disrupt cholesterol metabolism in Mtb, thereby inhibiting bacterial proliferation. Mtb-IN-10 holds potential for tuberculosis (TB) research, particularly for combating multidrug-resistant (MDR-TB) and extensively drug-resistant (XDR-TB) Mtb strains.
    Mtb-IN-10
  • HY-134940S
    Quabodepistat-d7
    Inhibitor
    Quabodepistat-d7 (OPC-167832-d7) is deuterium labeled Quabodepistat. Quabodepistat (OPC-167832) is a potent and orally active dprE1 inhibitor with?an IC50 of 0.258 μM. Quabodepistat has antituberculosis activity and can be used for the research of tuberculosis?caused by?Mycobacterium tuberculosis.
    Quabodepistat-d<sub>7</sub>
  • HY-B1568AR
    Bromodiphenhydramine hydrochloride (Standard)
    Inhibitor
    Bromodiphenhydramine (hydrochloride) (Standard) is the analytical standard of Bromodiphenhydramine (hydrochloride). This product is intended for research and analytical applications. Bromodiphenhydramine hydrochloride is a potent antihistamine with antimicrobial property. Bromodiphenhydramine hydrochloride inhibits a large number of Gram negative and Gram positive bacteria. Bromodiphenhydramine hydrochloride can be used for cutaneous allergies research.
    Bromodiphenhydramine hydrochloride (Standard)
Cat. No. Product Name / Synonyms Application Reactivity