1. Signaling Pathways
  2. Anti-infection
  3. Bacterial

Bacterial

Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N14306
    Aspersitin
    Inhibitor
    Aspersitin is a metabolite of Aspergillus parasiticus with antibacterial activity.
    Aspersitin
  • HY-B0458R
    Cefprozil monohydrate (Standard)
    Inhibitor
    Cefprozil monohydrate (Standard) is the analytical standard of Cefprozil monohydrate (HY-B0458). This product is intended for research and analytical applications. Cefprozil monohydrate is a second-generation cephalosporin type antibiotic. Cefprozil monohydrate exhibits broad-spectrum antibacterial activity, and is orally active. Cefprozil monohydrate can be used for the study of pharyngitis, tonsillitis, otitis media, and uncomplicated skin infections.
    Cefprozil monohydrate (Standard)
  • HY-170650
    SMase-IN-1
    SMase-IN-1 (Compound 4) is a bacterial sphingomyelinase enzyme (SMase) inhibitor (IC50 value for B. cereus SMase is 6.43 µM). SMase-IN-1 also inhibits eqBuChE (59.50% inhibition rate at 50 µM concentration). SMase-IN-1 forms a complex with Cu2+ in biometal interactions. SMase-IN-1 reduces B. cereus-induced hemolysis on sheep erythrocytes.
    SMase-IN-1
  • HY-17395AR
    Terbinafine (Standard)
    Inhibitor
    Terbinafine (Standard) is the analytical standard of Terbinafine. This product is intended for research and analytical applications. Terbinafine (TDT 067) is an orally active and potent antifungal agent. Terbinafine is a potent non-competitive inhibitor of squalene epoxidase from Candida, with a Ki of 30 nM. Terbinafine also shows antibacterial activity against certain Gram-positive and Gram-negative bacteria. Terbinafine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Terbinafine (Standard)
  • HY-N14260
    Hypelcin A-II
    Inhibitor
    Hypelcin A-II has anti-Gram-negative bacterial and fungal activity.
    Hypelcin A-II
  • HY-14519AR
    Methotrexate disodium (Standard)
    Methotrexate (disodium) (Standard) is the analytical standard of Methotrexate (disodium). This product is intended for research and analytical applications. Methotrexate (Amethopterin) disodium, an antimetabolite and antifolate agent, inhibits the enzyme dihydrofolate reductase, thereby preventing the conversion of folic acid into tetrahydrofolate, and inhibiting DNA synthesis. Methotrexate disodium, also an immunosuppressant and antineoplastic agent, is used for the research of rheumatoid arthritis and a number of different cancers (such as acute lymphoblastic leukemia).
    Methotrexate disodium (Standard)
  • HY-168861
    NDM-1 inhibitor-8
    Inhibitor
    NDM-1 inhibitor-8 (Compound 18b) is the covalent inhibitor for new delhi metallo-β-lactamase-1 (NDM-1) with an IC50 of 7.03 μM. NDM-1 inhibitor-8 inhibits the drug resistant strains, exhibits synergistic antibacterial effect with the use of Meropenem (HY-13678). NDM-1 inhibitor-8 exhibits anti-infectious activity in mouse models.
    NDM-1 inhibitor-8
  • HY-N14422
    Collismycin B
    Inhibitor
    Collismycin B is a potent dexamethasone-glucocorticoid receptor inhibitor with an IC50 value of 10 µM. Collismycin B shows antimicrobial activity. Collismycin B shows cytotoxicity.
    Collismycin B
  • HY-W653936
    Cephalexin-d5 hydrate
    Inhibitor
    Cephalexin-d5 (hydrate) is deuterium labeled Cephalexin (monohydrate). Cephalexin (Cefalexin) monohydrate is a potent, orally active new semisynthetic cephalosporin antibiotic with a broad antibacterial spectrum. Cephalexin (Cefalexin) monohydrate has antibacterial activity against a wide variety of gram-positive and gram-negative bacteria. Cephalexin (Cefalexin) monohydrate targets penicillin-binding proteins (PBPs) to inhibit bacterial cell wall assembly. Cephalexin (Cefalexin) monohydrate is used for the research of pneumonia, strep throat, and bacterial endocarditis, et al.
    Cephalexin-d<sub>5</sub> hydrate
  • HY-120009
    Showdomycin
    Inhibitor
    Showdomycin is an antibiotic produced by IM-2-induced in Streptomyces.
    Showdomycin
  • HY-N15516
    Pipcroside A
    Inhibitor
    Pipcroside A is found in P. crocatum Ruiz & Pav. Pipcroside A has antibacterial activity and can be used in the study of oral infections.
    Pipcroside A
  • HY-N14176
    Cyathin A3
    Inhibitor
    Cyathin A3 has weak activity against Gram-positive bacteria, negative bacteria, actinomycetes and dermatophytes, and has anti-ischemia effect (improving cerebral ischemia in rat model).
    Cyathin A3
  • HY-163069
    Antitubercular agent-43
    Inhibitor
    Antitubercular agent-43 (compound A11) is an orally active and potent antitubercular agent. Antitubercular agent-43 shows highly metabolic stability against human and mouse cytochrome P450 enzymes. Antitubercular agent-43 exhibits bactericidal efficacy in acute TB infection mouse model.
    Antitubercular agent-43
  • HY-174852
    Antibacterial agent 285
    Inhibitor
    Antibacterial agent 285 (Compound 3) is a cephalosporin antibiotic. Antibacterial agent 285 has significant antibacterial activity against gram-negative bacterium with MICs of 0.125-0.5, 0.125-0.5 and 0.125-2 μg/mL for carbapenem-resistant Acinetobacter baumannii (CRAB), Klebsiella pneumoniae (CRE) and Pseudomonas aeruginosa (CRPA), respectively. Antibacterial agent 285 can be used for bacterial infection research, such as complicated urinary tract infections (cUTI) and kidney infections.
    Antibacterial agent 285
  • HY-N14091
    Chrysospermin D
    Inhibitor
    Chrysospermin D has antibacterial activities against individual Gram-positive bacteria (Staphylococcus aureus, Bacillus subtilis), Klebsiella pneumoniae and individual yeasts (Ocher echinoderma, saccharomyces cerevisiae).
    Chrysospermin D
  • HY-168844
    Antibacterial agent 259
    Inhibitor
    Antibacterial agent 259 (K3) is a bactericide, with EC50 values ​​of 1.5, 1.7 and 4.9 mg/L for Xoo, Xoc and Xac, respectively. Antibacterial agent 259 can induce pathogens to produce reactive oxygen species (ROS), leading to their death. Antibacterial agent 259 can be used in the prevention and control of plant bacterial diseases.
    Antibacterial agent 259
  • HY-157618
    18:0-18:1 PG sodium
    ≥99.0%
    18:0-18:1 PG sodium is a hydrogenated phospholipid that contributes to the stability of photosystem I and II protein complexes and plays a role in bacterial defense mechanisms, featuring two extra methylene groups in its saturated sn-1 chain, and is present in the thylakoid membranes of higher plants and cyanobacteria.
    18:0-18:1 PG sodium
  • HY-14137S
    Rimonabant-d10 hydrochloride
    Inhibitor
    Rimonabant-d10 (hydrochloride) is the deuterium labeled Rimonabant hydrochloride. Rimonabant hydrochloride (SR 141716A hydrochloride) is a highly potent and selective central cannabinoid receptor (CB1) antagonist with an Ki of 1.8 nM. Rimonabant hHydrochloride (SR 141716A Hydrochloride) also inhibits Mycobacterial membrane protein Large 3 (MMPL3).
    Rimonabant-d<sub>10</sub> hydrochloride
  • HY-125365R
    Rifamycin S (Standard)
    Inhibitor
    Rifamycin S (Standard) is the analytical standard of Rifamycin S. This product is intended for research and analytical applications. Rifamycin S, a quinone, is an antibiotic against Gram-positive bacteria (including MRSA). Rifamycin S is the oxidized forms of a reversible oxidation-reduction system involving two electrons. Rifamycin S generates reactive oxygen species (ROS) and inhibits microsomal lipid peroxidation. Rifamycin S can be used for tuberculosis and leprosy.
    Rifamycin S (Standard)
  • HY-W337872
    N-(3-Hydroxyoctanoyl)-L-homoserine lactone
    Inhibitor
    N-(3-Hydroxyoctanoyl)-L-homoserine lactone (compound 11), a hydroxyl-containing N-acyl l-homoserine lactone (AHL) ligand, is a competitive AbaR and LasR inhibitor.
    N-(3-Hydroxyoctanoyl)-L-homoserine lactone
Cat. No. Product Name / Synonyms Application Reactivity