1. Signaling Pathways
  2. Anti-infection
  3. Bacterial

Bacterial

Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N14088
    Chrysospermin A
    Inhibitor
    Chrysospermin A has antibacterial activities against individual Gram-positive bacteria (Staphylococcus aureus, Bacillus subtilis), Klebsiella pneumoniae and individual yeasts (Ocher echinoderma, saccharomyces cerevisiae).
    Chrysospermin A
  • HY-B0519AS
    Tylosin-d3
    Inhibitor
    Tylosin-d3 is the deuterium labeled Tylosin. Tylosin (Tylosin A) is a macrolide antibiotic found naturally as a fermentation product of Streptomyces fradiae. Tylosin exerts potent antimicrobial activity against Gram-positive bacteria. Tylosin is widely used as a feed additive for promoting animal growth. Tylosin is used for veterinary purposes against bacterial dysentery and respiratory diseases in poultry, pigs and cattle.
    Tylosin-d<sub>3</sub>
  • HY-136954
    LL-BM123γ2
    Inhibitor
    LL-BM123γ2 is an antibacterial agent which is active against a variety of microorganisms. LL-BM123γ2 can be used for antibacterial research.
    LL-BM123γ2
  • HY-17035R
    Doramectin (Standard)
    Doramectin (Standard) is the analytical standard of Doramectin. This product is intended for research and analytical applications. Doramectin is a derivative of Ivermectin (HY-15310). Doramectin is a potent antiparasitic antibiotic. Doramectin is an active compound against S.mansoni in an NMRI mouse infection model.
    Doramectin (Standard)
  • HY-N14106
    Cinerubin R
    Inhibitor
    Cinerubin R has anti-Gram-positive bacteria and inhibition of tumor cell activity, and its inhibition effect on multidrug resistant (MDR) cells is the same as that on protocells.
    Cinerubin R
  • HY-161988
    Antimicrobial agent-34
    Inhibitor
    Antimicrobial agent-34 (compound 4h) is an antibacterial agent (MIC = 1–4 μg/mL), with a clogP value of 9.14. Antimicrobial agent-34 has good plasma stability (HC50 of 131.1 μg/mL) and good membrane selectivity (HC50/MIC is 65.6), with rapid sterilization capability. Antimicrobial agent-34 destroys the integrity of bacterial cell membranes, induces an increase in intracellular reactive oxygen species, and leaks protein and DNA, ultimately leading to bacterial death. Antimicrobial agent-34 demonstrates significant in vivo antibacterial potency in a mouse sepsis model infected with Staphylococcus aureus ATCC43300.
    Antimicrobial agent-34
  • HY-N14787
    Basidalin
    Inhibitor
    Basidalin has the ability of anti-Gram-positive bacteria, negative bacteria and inhibition of mouse leukemia L-1210 cell.
    Basidalin
  • HY-W740028
    Cefditoren-d3 sodium
    Inhibitor
    Cefditoren-d3 (sodium) (ME 1206-d3) is deuterium labeled Cefditoren (sodium). Cefditoren sodium (ME 1206) is a broad-spectrum, third-generation, oral cephalosporin antibacterial with enhanced stability against many common β lactamases. Cefditoren sodium has activity against Gram-negative organisms and Gram-positive organisms. Cefditoren sodium can be used in the research of infection diseases such as acute exacerbations of chronic bronchitis, community-acquired pneumonia (CAP), streptococcal pharyngitis/tonsillitis, or uncomplicated skin and skin structure infections.
    Cefditoren-d<sub>3</sub> sodium
  • HY-163142
    Antibacterial agent 172
    Inhibitor
    Antibacterial agent 172 (Compound 6a) is a <,i>Clostridioides difficile (Cd) SpoVD inhibitor (IC50=89 nM) that effectively inhibits sporulation of Clostridioides difficile. Antibacterial agent 172 can be used in the study of bacterial infections.
    Antibacterial agent 172
  • HY-105717
    Meralein sodium
    Inhibitor
    Meralein sodium is an antiseptic agent.
    Meralein sodium
  • HY-170970
    Mtb-IN-10
    Inhibitor
    Mtb-IN-10 (Compound P15) is a Rv1625c/Cya activator that regulates cAMP metabolism to influence the growth of Mycobacterium tuberculosis (Mtb). Mtb-IN-10 exhibits an EC50 of 1.96 µM in an Mtb-infected macrophage model and demonstrates 58.0% oral bioavailability in mice at a 20 mg/kg dose. It may regulate intracellular signaling and disrupt cholesterol metabolism in Mtb, thereby inhibiting bacterial proliferation. Mtb-IN-10 holds potential for tuberculosis (TB) research, particularly for combating multidrug-resistant (MDR-TB) and extensively drug-resistant (XDR-TB) Mtb strains.
    Mtb-IN-10
  • HY-134940S
    Quabodepistat-d7
    Inhibitor
    Quabodepistat-d7 (OPC-167832-d7) is deuterium labeled Quabodepistat. Quabodepistat (OPC-167832) is a potent and orally active dprE1 inhibitor with?an IC50 of 0.258 μM. Quabodepistat has antituberculosis activity and can be used for the research of tuberculosis?caused by?Mycobacterium tuberculosis.
    Quabodepistat-d<sub>7</sub>
  • HY-B1568AR
    Bromodiphenhydramine hydrochloride (Standard)
    Inhibitor
    Bromodiphenhydramine (hydrochloride) (Standard) is the analytical standard of Bromodiphenhydramine (hydrochloride). This product is intended for research and analytical applications. Bromodiphenhydramine hydrochloride is a potent antihistamine with antimicrobial property. Bromodiphenhydramine hydrochloride inhibits a large number of Gram negative and Gram positive bacteria. Bromodiphenhydramine hydrochloride can be used for cutaneous allergies research.
    Bromodiphenhydramine hydrochloride (Standard)
  • HY-N14675
    Helvecardin B
    Inhibitor
    Helvecardin B is a glycopeptidtic antibiotic. Helvecardin B has strong activity of anti-aerobic and anaerobic Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus.
    Helvecardin B
  • HY-B1297R
    Ceforanide (Standard)
    Inhibitor
    Ceforanide (Standard) is the analytical standard of Ceforanide. This product is intended for research and analytical applications. Ceforanide is a semisynthetic parental cephalosporin antibiotic, derived from 7-aminocephalosporanic acid. Ceforanide has antibacterial activity and is a potent inhibitor of most species of streptococci, excluding enterococci.
    Ceforanide (Standard)
  • HY-Y0367R
    Maleic Acid (Standard)
    Inhibitor
    Maleic Acid (Standard) is the analytical standard of Maleic Acid. This product is intended for research and analytical applications. Maleic Acid is a Glutamate Decarboxylase (GAD) inhibitor of E. coli and L. monocytogenes. IC50 & Target: GAD. In Vitro: The MICs of WT 10403S for the acids (e.g., Maleic Acid) are 34 mM, 25 mM, 31 mM and 30 mM which correspond to pH values prior to growth of 4.84, 5.14, 5.32 and 5.02 respectively. Of all compounds tested, Maleic Acid is the least inhibitory despite acting at a lower pH (4.84). The most acid resistant (10403S) and the weakest (EGD-e) strain are challenged with 8.6 mM and 4.3 mM of each organic acid at pH 3 and 3.3 respectively. On both strains, Maleic Acid is the most bactericidal.
    Maleic Acid (Standard)
  • HY-N14576
    Pyrrolomycin C
    Inhibitor
    Pyrrolomycins C is a member of the pyrrolomycin group of antibiotic found in the Actinosporangium sp.
    Pyrrolomycin C
  • HY-N14328
    Micacocidin B
    Inhibitor
    Micacocidin B is an antibiotic found in Pseudomonas sp.No.57. Micacocidin B exhibits an excellent activity against Mycoplasma species.
    Micacocidin B
  • HY-N13920
    Avilamycin C
    Inhibitor
    Avilamycin C is an avilamycin-type antibiotic. Avilamycin C has antibacterial activity and can inhibit Gram-positive bacteria.
    Avilamycin C
  • HY-W099540
    OES2-0017
    Inhibitor
    OES2-0017 shows potent synergy with polyamines and growth-inhibitory effects at the low micromolar range. OES2-0017 inhibits spermine/spermidine acetyltransferase (SpeG) (IC50: 34.82 μM ) and other polyamine detoxification enzymes in low concentrations, perturbed the bacterial membrane in higher concentrations.
    OES2-0017
Cat. No. Product Name / Synonyms Application Reactivity