1. Signaling Pathways
  2. Anti-infection
  3. Bacterial

Bacterial

Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-178101
    WRS22
    Inhibitor
    WRS22, a derivative of Tirabrutinib (HY-15771), is a bacterial Tryptophanyl-tRNA synthetase (TrpRS) inhibitor with a Kd of 0.33 μM for EcTrpRS. WRS22 can be used for antibiotic resistance research.
    WRS22
  • HY-N14277
    Miyakamide B2
    Inhibitor
    Miyakamide B2 is an antibiotic with insecticidal effect. Miyakamide B2 inhibits the growth of Artemia salina. Miyakamide B2 has a weak antixanthomonas activity. Miyakamide B2 inhibits P388 cells with an IC50 of 7.6 μg/mL.
    Miyakamide B2
  • HY-W002677R
    Fluoroquinolonic acid (Standard)
    Inhibitor
    Fluoroquinolonic acid (Standard) is the analytical standard of Fluoroquinolonic acid. This product is intended for research and analytical applications. Fluoroquinolonic acid is a bacteriostatic antibiotic. Fluoroquinolonic acid has broad-spectrum activity against Gram-positive and Gram-negative bacteria.
    Fluoroquinolonic acid (Standard)
  • HY-17628S1
    Cefiderocol-d6
    Inhibitor
    Cefiderocol-d6 (S-649266-d6) is a deuterated labeled Cefiderocol (HY-17628). Cefiderocol is a siderophore cephalosporin which has a potent activity against a broad range of aerobic Gram-negative bacterial species with MIC50s of 2 μg/mL or less.
    Cefiderocol-d<sub>6</sub>
  • HY-W590539
    ω-azido-C6 Ceramide
    Inhibitor
    ω-azido-C6 Ceramide reduces the membrane potential, and exhibits antibacterial activity against Neisseria, with MIC of 2 µg/ml for N. meningitidis MC58 and N. gonorrhoeae FA1090.
    ω-azido-C6 Ceramide
  • HY-B0975AR
    Penicillin V (Standard)
    Inhibitor
    Penicillin V (Standard) is the analytical standard of Penicillin V. This product is intended for research and analytical applications. Penicillin V (Phenoxymethylpenicillin) is a potent and orally active antibiotic. Penicillin V shows antibacterial activity for Streptococci, Clostridium difficile and staphylococcus aureus. Penicillin V has the potential for the research of otitis, sinusitis, pharyngitis and tonsillitis[4].
    Penicillin V (Standard)
  • HY-N14999
    Decatromicin A
    Inhibitor
    Decatromicin A is an antibiotic that can be isolated from Actinomadura MK73-NF4. Decatromicin A has anti-gram-positive bacterial activity.
    Decatromicin A
  • HY-B1222AR
    Sisomicin (Standard)
    Inhibitor
    Sisomicin (Standard) is the analytical standard of Sisomicin. This product is intended for research and analytical applications. Sisomicin is a broad-spectrum aminoglycoside antibiotic produced by Micromonospora inyoensis. Sisomicin is highly active against Gram-positive bacteria.
    Sisomicin (Standard)
  • HY-N14970
    Hexacyclinol
    Inhibitor
    Hexacyclinol has moderate anti-Gram-positive bacteria activity, 4-40 μg/mL can inhibit the production of oxidants by polymorphonuclear neutrophils (PMNL) stimulated by zymosan. Hexacyclinol inhibits the growth of L-930 and K 562 cells with IC50s of 1.4 μg/mL and 0.4 μg/mL, respectively, and the IC50 of HeLa cells is 10 μg/mL. Hexacyclinol also has an anti-Plasmodium effect, and its IC50 for Plasmodium falciparum is 2.4 μg/mL.
    Hexacyclinol
  • HY-B0947S
    Sulfanitran-d4
    Sulfanitran-d4 is the deuterium labeled Sulfanitran. Sulfanitran is an antibacterial and anticoccidial agent used in poultry feeds. Sulfanitran also is a multidrug resistance protein 2 (MRP2) stimulator that can increase the affinity of MRP2 for estradiol-17-β-D-glucuronide (E217βG).
    Sulfanitran-d<sub>4</sub>
  • HY-B1387R
    Sulfamethoxypyridazine (Standard)
    Inhibitor
    Sulfamethoxypyridazine (Standard) is the analytical standard of Sulfamethoxypyridazine. This product is intended for research and analytical applications. 0
    Sulfamethoxypyridazine (Standard)
  • HY-N14736
    Drosophilin
    Inhibitor
    Drosophilin is an antibacterial agent found in fungi, including Drosophilin A, B, C, and D. Drosophilin inhibits the growth of Gram-positive bacteria.
    Drosophilin
  • HY-161827
    Anti-MRSA agent 14
    Inhibitor
    Anti-MRSA agent 14 (Compound C17) has antibacterial agent against MRSA and MRSA-infected skin murine model. Anti-MRSA agent 14 is more potential than Norfloxacin (HY-B0132) against MRSA. Anti-MRSA agent 14 disrupts cell membrane and restrains metabolism. Anti-MRSA agent 14 shows antibacterial effects against S. aureus ATCC 6538, S. aureus ATCC 29213, S. epidermidis ATCC 12228, and MRSA with MIC values of 1, 2, 2, 1 μM respectively.
    Anti-MRSA agent 14
  • HY-A0130R
    Sulfalene (Standard)
    Inhibitor
    Sulfalene (Standard) is the analytical standard of Sulfalene. This product is intended for research and analytical applications. Sulfalene (Sulfametopyrazine) is an antimalarial agent. Sulfalene is also a long-acting sulfonamide antibacterial.
    Sulfalene (Standard)
  • HY-B0334R
    Sulbactam (Standard)
    Inhibitor
    Sulbactam (Standard) is the analytical standard of Sulbactam. This product is intended for research and analytical applications. Sulbactam (CP45899) is a competitive, irreversible beta-lactamase inhibitor. Sulbactam shows antimicrobial activity against multidrug-resistant (MDR) acinetobacter calcoaceticus--Acinetobacter baumannii (Acb) complex.
    Sulbactam (Standard)
  • HY-W587414
    Neospiramycin I
    Inhibitor
    Neospiramycin I is a macrolide antibiotic and a derivative of Spiramycin I (HY-N7141). Neospiramycin I is effective against the macrolide-sensitive KB210 strain of S. aureus, but ineffective against the macrolide-resistant KB224 strain, with minimum inhibitory concentrations (MIC) of 3.12 and greater than 100 µg/mL, respectively; it is also effective against B. cereus, B. subtilis, M. luteus, E. coli, and K. pneumoniae, with respective MIC values of 1.56, 3.12, 3.12, 0.2, 50, and 12.5 µg/mL. Neospiramycin I binds to the ribosomes of E. coli, with an inhibitory concentration 50 (IC50) of 1.2 µM. It protects mice from death in a type III S. pneumoniae infection model, with an effective dose 50 (ED50) of 399.8 mg/kg.
    Neospiramycin I
  • HY-17395AS1
    Terbinafine-d3
    Inhibitor
    Terbinafine-d3 (TDT 067-d3) is deuterium labeled Terbinafine. Terbinafine (TDT 067) is an orally active and potent antifungal agent. Terbinafine is a potent non-competitive inhibitor of squalene epoxidase from Candida, with a Ki of 30 nM. Terbinafine also shows antibacterial activity against certain Gram-positive and Gram-negative bacteria. Terbinafine is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    Terbinafine-d<sub>3</sub>
  • HY-N9709
    5-Hydroxysophoranone
    Inhibitor
    5-Hydroxysophoranone is a flavanone that can be isolated from the Erythrina subumbrans. 5-Hydroxysophoranone shows weak antibacterial activity against several strains of Streptococcus.
    5-Hydroxysophoranone
  • HY-N14528
    Oganomycin A
    Inhibitor
    Oganomycin A is more stable than cephalosporin and resistant to Gram-positive and negative bacteria. And it is more effective against Gram-negative bacteria than Gram-positive bacteria.
    Oganomycin A
  • HY-17021A
    Esomeprazole magnesium salt
    Esomeprazole magnesium salt ((S)-Omeprazole magnesium salt) is a potent and orally active proton pump inhibitor and reduces acid secretion through inhibition of the H+, K+-ATPase in gastric parietal cells. Esomeprazole magnesium salt has the potential for symptomatic gastroesophageal reflux disease research.
    Esomeprazole magnesium salt
Cat. No. Product Name / Synonyms Application Reactivity