1. Signaling Pathways
  2. Anti-infection
  3. Bacterial

Bacterial

Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-126577
    Dactylocycline B
    Inhibitor
    Dactylocycline B, an antibiotic, is active against gram-positive bacteria, including tetracycline-resistant bacteria.
    Dactylocycline B
  • HY-W099582
    Myristamidopropyl dimethylamine
    Inhibitor
    Myristamidopropyl dimethylamine (MAPD) is an antimicrobial agent (including against bacteria and fungi) and an insecticide, exhibiting inhibitory activity against Pseudomonas aeruginosa, Staphylococcus aureus, Candida albicans, Fusarium solani, and Acanthamoeba polyphaga. Myristamidopropyl dimethylamine can be used in research on microbial-induced keratitis .
    Myristamidopropyl dimethylamine
  • HY-W793613
    Drimendiol
    Inhibitor
    Drimendiol (compound 1) is an active product that can be isolated from leaves and twigs of D. winterii. Drimendiol shows inhibition for C. albicans, S. aureus, and S. epidermidis biofilm formation with 50% biofilm inhibitory concentration values (BIC50s) of 25.5, 65.1, and 67.1 µg/ml, respectively.
    Drimendiol
  • HY-N14156
    Epelmycin B
    Inhibitor
    Epelmycin B has anti-Gram positive, negative bacteria and candida albicans activity, and has anti-leukemic L1210 activity, which is stronger than Aclacinomycin.
    Epelmycin B
  • HY-N14233
    Inosamycin A
    Inhibitor
    Inosamycin A is a broad-spectrum antimicrobial antibiotic.
    Inosamycin A
  • HY-N13895
    Auramycin B
    Inhibitor
    Auramycin B, an anthracycline antibiotic that shows marked antibacterial activity against Gram-positive bacteria. Auramycin B also exhibits antitumor activity against P388 and L1210 leukemia in mice.
    Auramycin B
  • HY-169810
    PKZ18
    Inhibitor
    PKZ18 is an antibiotic and inhibits bacterial growth, with MIC values of 32-64 μg/mL against most Gram-positive bacteria. PKZ18 inhibits in vivo transcription and translation of glycyl-tRNA synthetase mRNA. PKZ18 selectively targets stem I specifier loops in Gram-positive bacteria and directly reduces T-box transcriptional read-through of the associated genes. PKZ18 prevents the codon-anticodon reading required for tRNA binding and is refractory to resistance.
    PKZ18
  • HY-W414697
    4-Hydroxysphinganine (C17 base)
    Inhibitor
    4-Hydroxysphinganine C17 base (D-Ribo-phytosphingosine C17 base), also known as D-ribo-phytosphingosine or PHS, is a crucial compound present in the membranes of fungi, plants, bacteria, marine organisms, and mammalian tissues. It plays a vital role in preserving the structural integrity of membranes, regulating cellular growth, and mediating the heat stress response in yeast. Additionally, PHS serves as a precursor for the synthesis of important lipid mediators such as PHS 1-phosphate, inositol phosphorylceramide, and KRN7000 (the α-anomer of galactosylceramide). Furthermore, this phospholipid promotes keratinocyte differentiation, making it a valuable active ingredient in cosmetic formulations.
    4-Hydroxysphinganine (C17 base)
  • HY-159899
    DHFR-IN-22
    Inhibitor
    DHFR-IN-22 (Compound 8) is a DHFR (Dihydrofolate Reductase) inhibitor belonging to the class of 2,4-diaminopyrimidine compounds. DHFR-IN-22 exhibits significant inhibitory activity against purified DHFR enzyme and major species of nontuberculous mycobacteria (NTM), namely Mycobacterium avium and Mycobacterium abscessus. It shows an IC50 of 1.1 nM and MIC of 1.5 μg/mL against M. abscessus, and an IC50 of 6.3 nM and MIC of 0.1 μg/mL against M. avium. Additionally, it demonstrates an IC50 of 2100 nM against human DHFR. DHFR-IN-22 holds potential for studying novel strategies to combat NTM infections.
    DHFR-IN-22
  • HY-138796
    Griseolutein A
    Inhibitor
    Griseolutein A shows activitiy against Gram-positive and negative bacteria.
    Griseolutein A
  • HY-145462
    N-cis-Octadec-9Z-enoyl-L-homoserine lactone
    N-cis-octadec-9Z-enoyl-L-Homoserine lactone is a potent inhibitor of AhyI. AhyI (expressing acylhomoserine lactone) is responsible for the biosynthesis of autoinducer-1 (AI-1), commonly referred to as a quorum sensing (QS) signaling molecule, which plays an essential role in bacterial communication. N-cis-octadec-9Z-enoyl-L-Homoserine lactone is a competitive inhibitor of AI-1 biosynthesis.
    N-cis-Octadec-9Z-enoyl-L-homoserine lactone
  • HY-B1894AR
    Cefetamet pivoxil hydrochloride (Standard)
    Inhibitor
    Cefetamet pivoxil (hydrochloride) (Standard) is the analytical standard for Cefetamet pivoxil (hydrochloride). This product is intended for research and analytical applications. Cefetamet pivoxil hydrochloride is an oral third generation cephalosporin antibiotic.
    Cefetamet pivoxil hydrochloride (Standard)
  • HY-N14969
    Granaticin methyl ester
    Inhibitor
    Granaticin methyl ester is a quinone antibiotic. Granaticin methyl ester has anti-Gram positive bacteria and negative bacteria activity.
    Granaticin methyl ester
  • HY-NP020
    E.coli DH-5 alpha Bacterial protein
    Inhibitor
    E.coli DH-5 alpha Bacterial protein is a purified native protein from E.coli DH-5 alpha bacterial.
    E.coli DH-5 alpha Bacterial protein
  • HY-173254
    MurA-IN-6
    Inhibitor
    MurA-IN-6 (Compound L16) is a selective MurA inhibitor with an IC50 value of 26.63 μM. MurA-IN-6 exerts antibacterial activity by blocking the activity of MurA, which is crucial in bacterial cell wall synthesis.
    MurA-IN-6
  • HY-N15068
    1-Hydroxyoxaunomycin
    Inhibitor
    1-Hydroxyoxaunomycin is an antibiotic. 1-Hydroxyoxaunomycin inhibits U210 cell growth, DNA synthesis and RNA synthesis with IC50 of 0.0005 μg/mL, 1.00 μg/mL and 0.76 μg/mL respectively.
    1-Hydroxyoxaunomycin
  • HY-B0946R
    Sulfamonomethoxine (Standard)
    Inhibitor
    Sulfamonomethoxine (Standard) is the analytical standard of Sulfamonomethoxine (HY-B0946). This product is intended for research and analytical applications. Sulfamonomethoxine is an orally active sulfonamide antibiotic for veterinary use. Sulfamonomethoxine is also an inhibitor of dihydropteroate synthetase, which can block the synthesis of folic acid. Sulfamonomethoxine has antibacterial activity.
    Sulfamonomethoxine (Standard)
  • HY-N6670R
    Cefotetan (Standard)
    Inhibitor
    Cefotetan (Standard) is the analytical standard of Cefotetan. This product is intended for research and analytical applications. Cefotetan is a semisynthetic cephamycin antibiotic that exerts its bactericidal effects by inhibition of cell-wall synthesis.
    Cefotetan (Standard)
  • HY-N13897
    Avidinorubicin
    Inhibitor
    Avidinorubicin is an antibiotic found in Streptomyces avidinii, exhibiting activity against both Gram-positive and Gram-negative bacteria. Additionally, Avidinorubicin inhibits thrombin (HY-114164)-induced platelet aggregation, with an IC50 of 7.9 μM.
    Avidinorubicin
  • HY-N14158
    Epelmycin D
    Inhibitor
    Epelmycin D has anti-Gram positive, negative bacteria and candida albicans activity, and has anti-leukemic L1210 activity, which is stronger than Aclacinomycin.
    Epelmycin D
Cat. No. Product Name / Synonyms Application Reactivity