1. Signaling Pathways
  2. Anti-infection
  3. Bacterial

Bacterial

Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-P2291A
    Beta-defensin 103 isoform X1, pig TFA
    Inhibitor
    Beta-defensin 103 isoform X1, pig TFA is an antimicrobial peptide found in different living organisms, involved in the first line of defense in their innate immune response against pathogens.
    Beta-defensin 103 isoform X1, pig TFA
  • HY-P5680
    SpHistin
    Inhibitor
    SpHistin is an antimicrobial peptide (AMP). SpHistin can bind to LPS (HY-D1056) and permeabilize the bacterial membrane. SpHistin combined with Rifampicin (HY-B0272) and Azithromycin (HY-17506) promotes the intracellular uptake of the antibiotics and subsequently enhances the bactericidal activity of both agents against P. aeruginosa.
    SpHistin
  • HY-145158
    Temocillin
    Inhibitor
    Temocillin, a 6-alpha-methoxy penicillin derivative, is a semisynthetic beta-lactam antibiotic with a spectrum of activity against most aerobic Gram-negative bacteria.
    Temocillin
  • HY-P5631
    Rabbit neutrophil peptide 3b
    Rabbit neutrophil peptide 3b is an antimicrobial peptide derived from rabbit peritoneal neutrophils.
    Rabbit neutrophil peptide 3b
  • HY-B0965AR
    Thioridazine (Standard)
    Inhibitor
    Thioridazine (Standard) is the analytical standard of Thioridazine. This product is intended for research and analytical applications. Thioridazine, an antagonist of the dopamine receptor D2 family proteins, exhibits potent anti-psychotic and anti-anxiety activities. Thioridazine is also a potent inhibitor of PI3K-Akt-mTOR signaling pathways with anti-angiogenic effect. Thioridazine shows antiproliferative and apoptosis induction effects in various types of cancer cells, with specificity on targeting cancer stem cells (CSCs).
    Thioridazine (Standard)
  • HY-108875
    Erythromycin stearate
    Inhibitor
    Erythromycin stearate is a macrolide antibiotic produced by actinomycete Streptomyces erythreus with a broad spectrum of antimicrobial activity. Erythromycin stearate binds to bacterial 50S ribosomal subunits and inhibits RNA-dependent protein synthesis by blockage of transpeptidation and/or translocation reactions, without affecting synthesis of nucleic acid[1][2]. Erythromycin stearate also exhibits antitumor and neuroprotective effect in different fields of research[3][4].
    Erythromycin stearate
  • HY-Y1825R
    Benzimidazole (Standard)
    Inhibitor
    Benzimidazole (Standard) is the analytical standard of Benzimidazole. This product is intended for research and analytical applications. Benzimidazole is a biochemical reagent that can be used as a biological material or organic compound for life science related research.
    Benzimidazole (Standard)
  • HY-B0614BR
    Mafenide hydrochloride (Standard)
    Inhibitor
    Mafenide (hydrochloride) (Standard) is the analytical standard of Mafenide (hydrochloride). This product is intended for research and analytical applications. Mafenide hydrochloride is an effective sulfonamide-type antimicrobial agent used for burn wounds. Mafenide hydrochloride shows activity against both Gram-positive and Gram-negative organisms, including Pseudomonas aeruginosa, via inhibition of nucleotide synthesis[1][2].
    Mafenide hydrochloride (Standard)
  • HY-146556
    Antitubercular agent-15
    Inhibitor
    Antitubercular agent-15 (Compound 5n) is an antitubercular agent with MIC90 values of 0.73, 7.69, 9.38, 18.80, 7.53 and 7.31 μg/mL against M. tuberculosis H37Rv, CF16, CF61, CF76, CF152 and CF161, respectively. Antitubercular agent-15 shows low cytotoxicity against macrophages and pulmonary fibroblasts.
    Antitubercular agent-15
  • HY-160611
    TgENR-IN-1
    Inhibitor
    TgENR-IN-1 (Compound 5a) is an inhibitor for Toxoplasma gondii enoyl reductase (TgENR), which inhibits 25% TgENR at 1 μM. TgENR-IN-1 exhibits toxicity with an IC50 of >10 μM in parasite tissue.
    TgENR-IN-1
  • HY-P5654
    Bombolitin IV
    Bombolitin IV is an antimicrobial peptide derived from bumblebee venom. Bombolitin IV can lysate erythrocyte and liposome.
    Bombolitin IV
  • HY-N12231
    Carbazomycin B
    Carbazomycin B is a bacterial metabolite and can be isolated from Streptomyces. Carbazomycin B is an antifungal and antibacterial agent. Carbazomycin B inhibits 5-lipoxygenase (5-LO) activity in extract from RBL-1 cell with the IC50 Of 1.5 µMsup>[2]sup>[3]sup>[4].
    Carbazomycin B
  • HY-153575
    BacPROTAC-1
    Inhibitor
    BacPROTAC-1 is a mSA BacPROTAC degrader. BacPROTAC-1 binds mSA and ClpCNTD with high affinity (KDs of 3.9 and 2.8 μM, respectively).
    BacPROTAC-1
  • HY-122071
    Bicyclomycin
    Inhibitor
    Bicyclomycin is an antibiotic. Bicyclomycin has anti-Bacterial activity against Gram-negative bacteria except Proteus and Pseudomonas aeruginosa.
    Bicyclomycin
  • HY-W018555R
    D-Cysteine (Standard)
    Inhibitor
    D-Cysteine (Standard) is the analytical standard of D-Cysteine. This product is intended for research and analytical applications. D-Cysteine, the D-isomer of cysteine, is an orally active antibacterial agent and a regulator of neural progenitor cell proliferation. D-Cysteine can inhibit Escherichia coli, Streptococcus mutans, and Streptococcus sanguinis. The no-observed-adverse-effect level of D-Cysteine in rats should be less than 500 mg/kg/day[1][2][3][4].
    D-Cysteine (Standard)
  • HY-P5463
    C18G
    Inhibitor
    C18G is a biological active peptide. (C18G is a synthetic α-helical peptide derived from human platelet factor IV. This peptide was found to be antibacterial and is active against Salmonella.)
    C18G
  • HY-103251R
    PF-5081090 (Standard)
    Inhibitor
    Cefalonium (dihydrate) (Standard) is the analytical standard of Cefalonium (dihydrate). This product is intended for research and analytical applications. Cefalonium dihydrate is a cephalosporin antibiotic. Cefalonium (dihydrate) is effective against Staphylococcus aureus. Cefalonium (dihydrate) has anti-inflammatory and antibacterial activities.
    PF-5081090 (Standard)
  • HY-B0656AR
    Rabeprazole sodium (Standard)
    Rabeprazole (sodium) (Standard) is the analytical standard of Rabeprazole (sodium). This product is intended for research and analytical applications. Rabeprazole sodium (LY307640 sodium) is a second-generation proton pump inhibitor (PPI) that irreversibly inactivates gastric H+/K+-ATPase. Rabeprazole sodium induces apoptosis. Rabeprazole sodium acts as an uridine nucleoside ribohydrolase (UNH) inhibitor with an IC50 of 0.3 μM. Rabeprazole sodium can be used for the research of gastric ulcerations and gastroesophageal reflux.
    Rabeprazole sodium (Standard)
  • HY-P5691
    P1
    Inhibitor
    P1 is a broad-spectrum antimicrobial peptide. P1 shows antibacterial activity against Gram-positive and Gram-negative bacteria,such as B. anthracis spores and Carbapenem-resistant A. baumannii and K. pneumoniae.
    P1
  • HY-N11422R
    Mycaminosyltylonolide (Standard)
    Inhibitor
    Deoxynivalenol (Standard) is the analytical standard of Deoxynivalenol. This product is intended for research and analytical applications. Deoxynivalenol, an orally active mycotoxin of the trichothecenes family, crosses the intestinal mucosa by a paracellular pathway through the tight junctions. The Deoxynivalenol transport is not affected by P-glycoprotein (PgP) or multidrug resistance-associated proteins (MRPs) inhibitors.
    Mycaminosyltylonolide (Standard)
Cat. No. Product Name / Synonyms Application Reactivity