1. Signaling Pathways
  2. Anti-infection
  3. Bacterial

Bacterial

Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-N12258
    Aranciamycin A
    Inhibitor
    Aranciamycin A is an anthracyclic antibiotic and can be isolated from Streptomyces. Aranciamycin A shows antibacterial activity against M. bovis and B. subtilis with the MIC values of 30 and 7.5 µM, respectively.
    Aranciamycin A
  • HY-149534
    DNA Gyrase-IN-9
    Inhibitor
    DNA Gyrase-IN-9 (compound 4j) is an antibacterial agent that targets DNA gyrase. The MIC to inhibit Gram bacteria is 0.5-2 μg/mL, and the MBC to kill Gram bacteria is 2-8 μg/mL. DNA Gyrase-IN-9 inhibits DNA gyrase in Staphylococcus aureus with IC50=6.29 μg/mL.
    DNA Gyrase-IN-9
  • HY-B1584R
    Captan (Standard)
    Inhibitor
    Captan (Standard) is the analytical standard of Captan. This product is intended for research and analytical applications. Captan is a common agricultural fungicide used to control Botrytis, Fusarium, Fusicoccum, Pythium. Captan enhances denitrifying and total culturable bacteria.
    Captan (Standard)
  • HY-121922
    Dienone B
    Inhibitor
    Dienone B is a marine algicide with antibiotic activity against both Gram-positive and Gram-negative marine bacteria.
    Dienone B
  • HY-114604
    Propioxatin B
    Inhibitor
    Propioxatin B is a tricyclic sesquiterpenoid compound isolated from the root of vetiver grass. It has anti-tuberculosis activity and inhibitory effects on a variety of drug-resistant mutants of Mycobacterium tuberculosis. In computer simulation docking studies, it showed binding affinity with bacterial DNA gyrase and has a certain safety in vivo.
    Propioxatin B
  • HY-N1637
    1-Methyl-2-pentyl-4(1H)-quinolinone
    99.94%
    1-Methyl-2-pentyl-4(1H)-quinolinone, a quinolone alkaloid isolated from the fruits of Evodia Rutaecarpa, possesses antibacterial and cytotoxic activities for cancer cells.
    1-Methyl-2-pentyl-4(1H)-quinolinone
  • HY-B0421AR
    Mycophenolic acid sodium (Standard)
    Inhibitor
    Mycophenolic acid (sodium) (Standard) is the analytical standard of Mycophenolic acid (sodium). This product is intended for research and analytical applications. Mycophenolic acid sodium is a potent uncompetitive inosine monophosphate dehydrogenase (IMPDH) inhibitor with an EC50 of 0.24 μM. Mycophenolic acid sodium demonstrates antiviral effects against a wide range of RNA viruses including influenza. Mycophenolic acid sodium is an immunosuppressive agent. Antiangiogenic and antitumor effects.
    Mycophenolic acid sodium (Standard)
  • HY-17466A
    Sancycline hydrochloride
    Sancycline (6-Demethyl-6-deoxytetracycline) hydrochloride acts by reversibly binding to the 30 S ribosomal subunit and inhibiting protein translation by blocking entry of aminoacyl-tRNA into the ribosome a site similar to tetracycline (HY-A0107). Sancycline hydrochloride, four linearly fused six-membered rings with four stereocenters, is a rare semi-synthetic tetracycline (HY-A0107) prepared by hydrogenolysis of the chloro and benzylic hydroxy moieties of Declomycin.
    Sancycline hydrochloride
  • HY-111320
    Chrysomycin B
    Inhibitor
    Chrysomycin B is an antibiotic isolated from a strain of Streptomyces. Chrysomycin B causes DNA damage in the human lung adenocarcinoma A549 cell line and inhibits topoisomerase II. Chrysomycin B suppresses the growth of transplantable tumors in mice.
    Chrysomycin B
  • HY-B1431A
    Butylparaben sodium
    Inhibitor
    Butylparaben sodium strongly influences the later stages of the spermatogenesis in the testis through the deterioration of hormonal control and/or RNA and protein synthesis.
    Butylparaben sodium
  • HY-118149A
    (±)9-HpODE
    Inhibitor
    (±)9-HpODE is a long chain lipid hydroperoxide, is a product of linoleic acid peroxidation. (±)9-HpODE can induce oxidation of intracellular glutathione (GSH). (±)9-HpODE also exhibits antimicrobial activity against various fungal and bacterial pathogens.
    (±)9-HpODE
  • HY-146446R
    PXYC1 (Standard)
    Inhibitor
    Maltopentaose (Standard) is the analytical standard of Maltopentaose. This product is intended for research and analytical applications. Maltopentaose is the shortest chain oligosaccharide that can be classified as maltodextrin and is also used in a study to investigate glycation and phosphorylation of α-lactalbumin.
    PXYC1 (Standard)
  • HY-128850S2
    N-Acetyl-D-mannosamine-13C-1
    N-Acetyl-D-mannosamine-13C-1 is the 13C labeled N-Acetyl-D-mannosamine. N-Acetyl-D-mannosamine (ManNAc) is an essential precursor of N-acetylneuraminic acid (NeuAc), the specific monomer of bacterial capsular polysialic acid (PA)
    N-Acetyl-D-mannosamine-<sup>13</sup>C-1
  • HY-B0306S
    Prothionamide-d5
    Inhibitor
    Prothionamide-d5 is deuterium labeled Prothionamide (HY-B0306). Prothionamide is an orally active thioamide antibacterial agent. Prothionamide is a substrate of OCT1 with a Km value of 805.8 μM. Prothionamide reacts with NAD to form a covalent adduct, with the adduct being a tight-binding inhibitor of Mycobacterium tuberculosis and Mycobacterium leprae InhA. Prothionamide can effectively inhibit the growth of Mycobacterium tuberculosis (MIC = ~0.5 µg/mL) and Mycobacterium leprae. Prothionamide is used in the research of tuberculosis and leprosy.
    Prothionamide-d<sub>5</sub>
  • HY-N3789
    Dunnianol
    Inhibitor
    Dunnianol is a natural sesqui-neoligan with moderate antibacterial activity. Dunnianol inhibits Staphylococcus aureus and methicillin-resistant Staphylococcus aureus (MRSA).
    Dunnianol
  • HY-B1190S1
    Cefadroxil-d4 trifluoroacetate
    Inhibitor
    Cefadroxil-d4 (trifluoroacetate) is deuterium labeled Cefadroxil.
    Cefadroxil-d<sub>4</sub> trifluoroacetate
  • HY-66011AS3
    Moxifloxacin-d3-1 hydrochloride
    Inhibitor
    Moxifloxacin-d3-1 hydrochloride (BAY 12-8039-d3-1) is a deuterium labeled Moxifloxacin (HY-66011A). Moxifloxacin is an orally active 8-methoxyquinolone antimicrobial for use in the treatment of acute bacterial sinusitis, acute bacterial exacerbations of chronic bronchitis, and community-acquired pneumonia.
    Moxifloxacin-d<sub>3</sub>-1 hydrochloride
  • HY-168258
    Antibiofilm agent-13
    Inhibitor
    Antibiofilm agent-13 (compound 14b) is a potent antibacterial agent that displays a broad-spectrum antimicrobial activity. Antibiofilm agent-13 could disintegrate the integrity of bacterial cell membranes by destroying transmembrane potential and enhancing membrane permeability, and causing the generation of intracellular ROS and the leakage of DNA and proteins, ultimately leading to bacterial death. Antibiofilm agent-13 inhibits both Gram-positive bacteria (MIC of 0.5-1 μg/mL) and Gram-negative bacteria (MIC of 1-32 μg/mL).
    Antibiofilm agent-13
  • HY-158380
    UH-NIP-16
    Inhibitor
    UH-NIP-16 exhibits antimicrobial activity against Mycobacterium tuberculosis, with MIC50 of 1.86 and 3.05 μM, for pathogenic mycobacterial strains H37Rv and CDC1551. UH-NIP-16 synergizes with Streptomycin (HY-B1906), Isoniazid (HY-B0329), Ethambutol (HY-B0535) and Bedaquiline (HY-14881), potentiates their anti-tuberculosis activities.
    UH-NIP-16
  • HY-P1259
    PR-39
    Inhibitor
    PR-39, a natural proline- and arginine-rich antibacterial peptide, is a noncompetitive, reversible and allosteric proteasome inhibitor. PR-39 reversibly binds to the α7 subunit of the proteasome and blocks degradation of NF-κB inhibitor IκBα by the ubiquitin-proteasome pathway. PR-39 stimulates angiogenesis, inhibits inflammatory responses and significant reduces myocardial infarct size in mice.
    PR-39
Cat. No. Product Name / Synonyms Application Reactivity