1. Signaling Pathways
  2. Anti-infection
  3. Bacterial

Bacterial

Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-100584R
    Davercin (Standard)
    Inhibitor
    Maraviroc (Standard) is the analytical standard of Maraviroc. This product is intended for research and analytical applications. Maraviroc (UK-427857) is a selective CCR5 antagonist with activity against human HIV.
    Davercin (Standard)
  • HY-130281
    Ianthelliformisamine B diTFA
    Inhibitor
    Ianthelliformisamine B diTFA is a bromotyrosine-derived antibacterial agent. Ianthelliformisamine B diTFA is against E. coli and S. aureus strains with MICs of 14.5 μM and 144.7 μM.
    Ianthelliformisamine B diTFA
  • HY-17507AR
    Pantoprazole sodium (Standard)
    Pantoprazole (sodium) (Standard) is the analytical standard of Pantoprazole (sodium). This product is intended for research and analytical applications. Pantoprazole sodium (BY10232 sodium) is an orally active and potent proton pump inhibitor (PPI). Pantoprazole sodium, a substituted benzimidazole, is a potent H+/K+-ATPase inhibitor with an IC50 of 6.8 μM. Pantoprazole sodium improves pH stability and has anti-secretory, anti-ulcer activities. Pantoprazole sodium significantly increased tumor growth delay combined with Doxorubicin (HY-15142).
    Pantoprazole sodium (Standard)
  • HY-N1128
    Trichorabdal A
    Inhibitor
    Trichorabdal A is a diterpenoid compound isolated from Rabdosia trichocarpa. Trichorabdal A has potent anti-tumor activity.
    Trichorabdal A
  • HY-125654C
    Olanexidine (gluconate)
    Inhibitor
    Olanexidine gluconate is an antibacterial agent. Olanexidine gluconate is active against a wide range of bacteria, imcluding both Gram-positive and Gram-negative bacteria Olanexidine gluconate is also an antiseptic. Olanexidine gluconate can be used in the research of infection and inflammation.
    Olanexidine (gluconate)
  • HY-112586S1
    Sulfaethoxypyridazine-13C6
    Inhibitor
    Sulfaethoxypyridazine-13C6 is the 13C6 labeled Sulfaethoxypyridazine. Sulfaethoxypyridazine is a sulfonamide antibacterial agent. Sulfaethoxypyridazine is a sulfonamide that is used in veterinary medicine as feedstuffs.
    Sulfaethoxypyridazine-<sup>13</sup>C<sub>6</sub>
  • HY-121178
    Deoxyviolacein
    Inhibitor
    Deoxyviolacein is a bacterial metabolite and byproduct in the biosynthesis of the bisindole alkaloid violacein (HY-119809) that has anticancer, antibacterial, and antifungal properties. It inhibits proliferation of hepatocellular carcinoma cells when used at concentrations ranging from 0.1 to 1 μM. Deoxyviolacein (125 μg/mL) has antibacterial activity against Gram-positive bacteria, including S. aureus, B. subtilis, and B. megaterium. It also has antifungal activity against R. solani when used at a concentration of 2 mg/ml.
    Deoxyviolacein
  • HY-14926R
    Levonadifloxacin (Standard)
    Inhibitor
    Levonadifloxacin (Standard) is the analytical standard of Levonadifloxacin. This product is intended for research and analytical applications. Levonadifloxacin ((S)-(-)-Nadifloxacin; WCK 771) is a broad-spectrum anti-staphylococcal agent. Levonadifloxacin shows antibacterial activity against Methicillin (HY-121544)-susceptible Staphylococcus aureus (MSSA) and Methicillin-resistant S. aureus (MRSA) strains, with a reduction of which phagocytized in THP-1 monocytes[1].
    Levonadifloxacin (Standard)
  • HY-161406
    DXPS-IN-1
    Inhibitor
    DXPS-IN-1 (Compound 8) is an inhibitor of 1-deoxy-D-xylulose-5-phosphate synthase (DXPS) with a Ki value of 2.9 nM against EcDXPS. DXPS-IN-1 exhibits antibacterial activity.
    DXPS-IN-1
  • HY-B0732A
    Itopride
    Itopride (HSR803 free base) is a potent and orally active dopamine-2 antagonist and an acetylcholine esterase (AChE) inhibitor. Itopride enhances gastric motility through both antidopaminergic and anti-acetylcholinesterasic actions, can be used as a gastrointestinal prokinetic agent. Itopride can be used for researching gastro-esophageal reflux disease (GERD).
    Itopride
  • HY-162475
    Fluorofolin
    Inhibitor
    Fluorofolin is a dihydrofolate reductase (DHFR) inhibitor with an IC50 of 2.5 nM. Fluorofolin exhibits significant activity against P. aeruginosa.
    Fluorofolin
  • HY-113729
    B 746
    Inhibitor
    B746 is a clofazimine analog with anti-Mycobacterium avium complex (MAC) activity and is less effective when used with clofazimine or streptomycin.
    B 746
  • HY-158375
    MBL-IN-4
    Inhibitor
    MBL-IN-4 (compound 4b) is a MBL inhibitor with the IC50 of 4.81 and 33 μM against IMP-1 and NDM-1.
    MBL-IN-4
  • HY-123888
    Viomellein
    Inhibitor
    Viomellein is a SUMOylation inhibitor with antibacterial and anticancer activities. Viomellein inhibits biofilm formation of strains produced from the fungus Aspergillus ochraceus from the Mediterranean sponge Agelas oroides. Viomellein exhibits cytotoxicity against A2780 human ovarian cancer cells with an IC50 value of 5.0 μM. Viomellein also inhibits SUMOylation of RanGAP1 (GTPase activating protein) with an IC50 of 10.2 μM.
    Viomellein
  • HY-77995S
    2-Methoxybenzaldehyde-d3
    2-Methoxybenzaldehyde-d3 is the deuterium labeled 2-Methoxybenzaldehyde. 2-Methoxybenzaldehyde (o-Anisaldehyde), isolated from cinnamon essential oil (CEO), exists antibacterial and antifungal activity.
    2-Methoxybenzaldehyde-d<sub>3</sub>
  • HY-N0059R
    D-Arabinose (Standard)
    Inhibitor
    D-Arabinose (Standard) is the analytical standard of D-Arabinose. This product is intended for research and analytical applications. D-Arabinose is is an orally active antidepressant and a growth inhibitor of C. elegans (IC50 is 7.5 mM). D-Arabinose can penetrate the blood-brain barrier, selectively interfere with the metabolism of D-ribose and D-fructose, and inhibit the growth of nematodes. D-Arabinose can also inhibit the synthesis of cell biofilm and exert antibacterial activity. D-Arabinose activates the ACSS2-PPARγ/TFEB-CRTC1 axis through the lysosomal AXIN-LKB1-AMPK pathway, inducing CRTC1 transcription, exerts antidepressant-like activity. D-Arabinose is the ring-opened form of the aldopentose D-?Arabinose (HY-N7082).
    D-Arabinose (Standard)
  • HY-N0021R
    Verbascoside (Standard)
    Inhibitor
    Verbascoside (Standard) is the analytical standard of Verbascoside. This product is intended for research and analytical applications. Verbascoside is isolated from Acanthus mollis, acts as an ATP-competitive inhibitor of PKC, with an IC50 of 25 μM, and has antitumor, anti-inflammatory and antineuropathic pain activity.
    Verbascoside (Standard)
  • HY-B0239S2
    Threo-Chloramphenicol-d6
    Threo-Chloramphenicol-d6 is the deuterium labeled Chloramphenicol. Chloramphenicol is an orally active, potent and broad-spectrum antibiotic. Chloramphenicol shows antibacterial activity. Chloramphenicol represses the oxygen-labile transcription factor and hypoxia inducible factor-1 alpha (HIF-1α) in hypoxic A549 and H1299 cells. Chloramphenicol suppresses the mRNA levels of vascular endothelial growth factor (VEGF) and glucose transporter 1, eventually decreasing VEGF release. Chloramphenicol can be used for anaerobic infections and lung cancer research.
    Threo-Chloramphenicol-d<sub>6</sub>
  • HY-161135
    TBAJ-5307
    Inhibitor
    TBAJ-5307 is a broad spectrum anti-non-tuberculous mycobacteria inhibitor that can target the FO-domain of the engine and preventing rotation and proton-translocation. TBAJ-5307 inhibits non-tuberculous mycobacteria in vitro and in vivo.
    TBAJ-5307
  • HY-B0322AR
    Sulfamethoxazole sodium (Standard)
    Inhibitor
    Sulfamethoxazole (Standard) (Ro 4-2130 (Standard)) sodium is the analytical standard of Sulfamethoxazole sodium (HY-B0322A). This product is intended for research and analytical applications. Sulfamethoxazole (Ro 4-2130) sodium is a sulfonamide antibiotic with a widespread antibacterial activity. Sulfamethoxazole sodium inhibits bacterial folate metabolism by competing with 4-Aminobenzoic acid (HY-B1008) (PABA) to act on dihydropteroate synthetase and dihydropteroate reductase. Sulfamethoxazole sodium can be used for the study of urinary tract infections (UTIs), prostatitis, and bronchitis.
    Sulfamethoxazole sodium (Standard)
Cat. No. Product Name / Synonyms Application Reactivity