1. Signaling Pathways
  2. Anti-infection
  3. Bacterial

Bacterial

Anything that destroys bacteria or suppresses their growth or their ability to reproduce. Heat, chemicals such as chlorine, and antibiotic drugs all have antibacterial properties. Many antibacterial products for cleaning and handwashing are sold today. Such products do not reduce the risk for symptoms of viral infectious diseases in otherwise healthy persons. This does not preclude the potential contribution of antibacterial products to reducing symptoms of bacterial diseases in the home.

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-151875
    MurA-IN-3
    Inhibitor
    MurA-IN-3 is a reversible pyrrolidinedione-based MurA inhibitor. MurA-IN-3 has inhibitory activity for MurA with an IC50 value of 4.5 μM. MurA-IN-3 also has antibacterial activity.
    MurA-IN-3
  • HY-113289R
    Brassicasterol (Standard)
    Inhibitor
    L-Ornithine (hydrochloride) (Standard) is the analytical standard of L-Ornithine (hydrochloride). This product is intended for research and analytical applications. L-Ornithine hydrochloride is a non-proteinogenic amino acid, is mainly used in urea cycle removing excess nitrogen in vivo. L-Ornithine hydrochloride shows nephroprotective.
    Brassicasterol (Standard)
  • HY-17577R
    Berberine chloride hydrate (Standard)
    Inhibitor
    Berberine (chloride hydrate) (Standard) is the analytical standard of Berberine (chloride hydrate). This product is intended for research and analytical applications. Berberine chloride hydrate (Natural Yellow 18 chloride hydrate) is an alkaloid that acts as an antibiotic. Berberine chloride hydrate induces reactive oxygen species (ROS) generation and inhibits DNA topoisomerase. Antineoplastic properties[1].
    Berberine chloride hydrate (Standard)
  • HY-144279
    MsbA-IN-1
    MsbA-IN-1 is a highly potent MsbA inhibitor with IC50 of 4 nM. MsbA-IN-1 has activity against wild-type E. coli with MIC of 79 μM. MsbA-IN-1 possesses sufficient permeability across the fully intact outer membrane of Gram-negative bacteria to inhibit MsbA.
    MsbA-IN-1
  • HY-151357
    MraY-IN-3
    Inhibitor
    MraY-IN-3 (12a) is a potent bacterial translocase MraY inhibitor with an IC50 value of 140 µM. MraY-IN-3 acts on E. coli K12, B. subtilis W23 and P. fluorescens Pf-5 with the MIC50 values of 7 µg/mL, 12 µg/mL, and 46 µg/mL, respectively.
    MraY-IN-3
  • HY-146705
    PqsR-IN-1
    Inhibitor
    PqsR-IN-1 (Compound 18) is a potent PqsR (Pseudomonas aeruginosa quorum sensing transcriptional regulator) inhibitor. PqsR-IN-1 attenuates pyocyanin production and has very low cytotoxicity.
    PqsR-IN-1
  • HY-126475
    KSK213
    KSK213 is a 1,2,3-triazole-based Chlamydia infectivity inhibitor with high potency (EC50 ≤ 20 nM) against Chlamydia infectivity.
    KSK213
  • HY-W711323
    Flurofamide-d4
    Flurofamide-d4 is the deuterium labeled Flurofamide (HY-100956). Flurofamide is a potent bacterial urease inhibitor with potential in the treatment of infection induced urinary stones.
    Flurofamide-d<sub>4</sub>
  • HY-155283
    Zndm19
    Inhibitor
    Zndm19 is a New Delhi Metallo-β-lactamase-1 (NDM-1) inhibitor. Zndm19 can be used for the research of drug-resistant bacterial infections.
    Zndm19
  • HY-B1217S
    Bronopol-d4
    Inhibitor
    Bronopol-d4 is deuterium labeled Bronopol. Bronopol is an antibacterial agent with low toxicity (to mammals) and high activity (especially against Gram-negative bacteria). Bronopol oxidizes protein thiols, inhibits enzymatic activity, and exhibits antibacterial activity. Bronopol is also a formaldehyde releaser.
    Bronopol-d<sub>4</sub>
  • HY-P5949
    AMPR-22
    Inhibitor
    AMPR-22 is an antimicrobial peptide. AMPR-22 can bind to the bacterial membrane and induces membrane permeabilization. AMPR-22 is effective against murine model of sepsis induced by MDR strains
    AMPR-22
  • HY-114439
    MtbHU-IN-1
    Inhibitor
    MtbHU-IN-1 is an inhibitor of Mycobacterium tuberculosis nucleoid-associated protein HU (MtbHU), with a Kd of 98 nM for binding to WT MtbHU.
    MtbHU-IN-1
  • HY-114224
    TP-271
    Inhibitor
    TP-271 is a compound with the potential to inhibit community-acquired pneumonia.
    TP-271
  • HY-B1300A
    Cefonicid
    Inhibitor
    Pharmacokinetic studies of Cefonicid have shown that high blood concentrations can be achieved rapidly after intravenous and intramuscular injection, and that concomitant use of albendazole prolongs its half-life in the body and reduces the rate of renal excretion.
    Cefonicid
  • HY-P10596
    Lasioglossin-III
    Inhibitor
    Lasioglossin-III is an antimicrobial peptide that can be isolated from the venom of wild bees. Lasioglossin-III has high antibacterial activity against Gram-positive and Gram-negative bacteria, antifungal activity and antitumor activity. Lasioglossin-III has certain cytotoxicity against three cancer cell lines (HeLa S3, CRC SW 480 and CCRF-CEM T) with IC50 values ​​of 4, 18 and 5 μM, respectively.
    Lasioglossin-III
  • HY-135221R
    Cefcapene pivoxil hydrochloride (Standard)
    Inhibitor
    Chenodeoxycholic Acid (Standard) is the analytical standard of Chenodeoxycholic Acid. This product is intended for research and analytical applications. Chenodeoxycholic Acid is a hydrophobic primary bile acid that activates nuclear receptors (FXR) involved in cholesterol metabolism.
    Cefcapene pivoxil hydrochloride (Standard)
  • HY-P5681
    Human α-Defensin 6
    Inhibitor
    Human α-Defensin 6, a 32-residue cysteine-rich peptide, can inhibit bacterial invasion and contribute to the mucosal immunity. Human α-Defensin 6 forms ordered self-assembly fibrils and nanonets that surround and entangle bacteria after stochastic binding to bacterial surface proteins. Human α-Defensin 6 also inhibits C. albicans biofilm formation.
    Human α-Defensin 6
  • HY-N11137
    3′-Omethyl-5′-hydroxydiplacone
    Inhibitor
    3′-Omethyl-5′-hydroxydiplacone (compound 2), an C-6-geranylflavonoid, can be isolated from the ethanol extract of Paulownia tomentosa fruits. 3′-Omethyl-5′-hydroxydiplacone has antibacterial activity against Gram-positive bacteria.
    3′-Omethyl-5′-hydroxydiplacone
  • HY-W750848
    Raja 42-d10
    Raja 42-d10 is the deuterium labeled Raja 42 (HY-W749146). Raja 42 is a gamma lactam antibiotic. Raja 42 is effective against a variety of different bacterias, including Gram-positive and Gram-negative bacteria, such as C. difficile strains.
    Raja 42-d<sub>10</sub>
  • HY-146637
    VIM-2-IN-1
    Inhibitor
    VIM-2-IN-1 (compound 1dj) is a β-lactamase inhibitor with antibacterial activities. VIM-2-IN-1 has moderate IC50 values of 23 µM, 48 µM and 231 µM for Verona integron-encoded metallo-β-lactamase (VIM-2), German imipenemase-1 (GIM-1) and New Delhi metallo-β-lactamase (NDM-1), respectively.
    VIM-2-IN-1
Cat. No. Product Name / Synonyms Application Reactivity