2. Neurological Disease

Neurological Disease

Neurological Disease

Related Products

PDF 88.0 MB

A range of neurological disorders, including epilepsy and dystonia, may involve dysfunctional intracortical inhibition, and may respond to treatments that modify it. Parkinson’s is a neurodegenerative disease characterized by increased activity of GABA in basal ganglia and the loss of dopamine in nigrostriatum, associated with rigidity, resting tremor, gait with accelerating steps, and fixed inexpressive face. Neurological deficits, along with neuromuscular involvement, are characteristic of mitochondrial disease, and these symptoms can have a dramatic impact on patient quality of life. Neurological features may be manifold, ranging from neural deafness, ataxia, peripheral neuropathy, migraine, seizures, stroke‐like episodes and dementia and depend on the part of the nervous system affected.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-P3541
    Dirucotide 152074-97-0 98%
    Dirucotide (MBP8298) is a synthetic peptide that consists of 17 amino acids linked in a sequence identical to that of a portion of human myelin basic protein. Dirucotide can be used for the research in autoimmune disorder of the central nervous system, such as Multiple sclerosis (MS).
    Dirucotide
  • HY-P3546
    [DPen2, Pen5] Enkephalin 88373-72-2 98%
    [DPen2, Pen5] Enkephalin is a δ-opioid receptor selective analog of [Leu5]-Enkephalin (HY-P0288).
    [DPen2, Pen5] Enkephalin
  • HY-P3548
    [D-Ala2]-Met-Enkephalinamide 61090-95-7 98%
    [D-Ala2]-Met-Enkephalinamide, an opioid peptide, is a potent opioid agonist. [D-Ala2]-Met-Enkephalinamide decreases bile flow by a central mechanism. [D-Ala2]-Met-Enkephalinamide has analgesic properties.
    [D-Ala2]-Met-Enkephalinamide
  • HY-P3549
    [D-Ala2] Leu-Enkephalinamide 65189-64-2 98%
    [D-Ala2] Leu-Enkephalinamide is an enkephalin analog. [D-Ala2] Leu-Enkephalinamide has great corneal permeability and analgesic effect. [D-Ala2] Leu-Enkephalinamide can be used for the research of ocular diseases.
    [D-Ala2] Leu-Enkephalinamide
  • HY-P3550
    β-Lipotropin (60-65) 60117-19-3 98%
    β-Lipotropin (60-65) (β-LPH (60-65)), an opioid peptide, is a potent opioid agonist.
    β-Lipotropin (60-65)
  • HY-P3553
    Alsactide 34765-96-3 98%
    Alsactide, a heptadecapeptide analogue, is an adrenocorticotropic hormone (ACTH) agonist. Alsactide can be used in research of central nervous system.
    Alsactide
  • HY-P3561
    Agouti-related Protein (AGRP) (83-132) Amide (human) 98%
    Agouti-related Protein (AGRP) (83-132) Amide (human) is a fragment of agouti-related protein (AGRP) which is a protein found in abundance in the arcuate nucleus of the hypothalamus. AgRP primarily acts as an inverse agonist for the melanocortin-4 receptor (MC4R) to increase food intake.
    Agouti-related Protein (AGRP) (83-132) Amide (human)
  • HY-P3567
    (p-Iodo-Phe7)-ACTH (4-10) 159600-82-5 98%
    (p-Iodo-Phe7)-ACTH (4-10) is a adrenocorticotrophic hormone (ACTH) derivative, which is produced and secreted by the anterior pituitary gland. (p-Iodo-Phe7)-ACTH (4-10) serves as a melanocortin (MC) receptor antagonist and inhibits α-melanocyte-stimulating hormone (α-MSH)-induced excessive grooming behavior in rats.
    (p-Iodo-Phe7)-ACTH (4-10)
  • HY-P3576
    Biotin-Gastrin Releasing Peptide, human 98%
    Biotin-Gastrin Releasing Peptide, human is a biotinylated gastrin releasing peptide (GRP). Gastrin-releasing peptide (GRP) is a neuropeptide with growth-stimulatory and tumorigenic properties.
    Biotin-Gastrin Releasing Peptide, human
  • HY-P3591
    YMRF-NH2 83903-32-6 98%
    YMRF-NH2 is a neuropeptide. YMRF-NH2 binds to FMRFa-R with an EC50 value of 31 nM.
    YMRF-NH2
  • HY-P3593
    LPLRF-NH2 88280-21-1 98%
    LPLRF-NH2 is a member of RFamide peptide with anorexigenic effect. LPLRF-NH2 increases arterial blood pressure and modulates the electrical activity of brainstem neurons.
    LPLRF-NH2
  • HY-P3625
    Dynorphin (2-17), amide (porcine) 161874-98-2 98%
    Dynorphin (2-17), amide (porcine) is a dynorphin derivative with some analgesic effects. Dynorphin is a class of opioid peptides produced by the precursor protein dynorphinogen and is involved in pain, addiction and mood regulation.
    Dynorphin (2-17), amide (porcine)
  • HY-P3628
    Dynorphin (2-17) (porcine) 83608-80-4 98%
    Dynorphin (2-17) (porcine) is a peptide derived from Prodynorphin, can improve somatic signs of Morphine-dependent withdrawal.
    Dynorphin (2-17) (porcine)
  • HY-P3629
    Dynorphin B 29 (pig) 84376-30-7 98%
    Dynorphin B 29 (Leumorphin) (pig) is a petide. Dynorphin B 29 (pig) can interact with multiple receptors in the brain, as well as in isolated tissue systems. Dynorphin B 29 (pig) can be used for the research of immunoreaction.
    Dynorphin B 29 (pig)
  • HY-P3631
    SALMF amide 2 134439-74-0 98%
    SALMF amide 2, a neuropeptide S2 from the starfish Asterias rubens, is involved in the regulation of eversion of the cardiac stomach in starfish.
    SALMF amide 2
  • HY-P3632
    [DAla2, DArg6] Dynorphin A, (1-13) (porcine) 75921-88-9 98%
    [DAla2, DArg6] Dynorphin A, (1-13) (porcine) (DADAD) is an opioid peptide (dynorphinl-13, DYN) derivative found in porcine pituitary extracts. DYN is highly potent at the peripheral opioid receptors GPI and MVD, but is readily and rapidly degraded in vivo. [DAla2, DArg6] Dynorphin A, (1-13) (porcine) has some resistance to enzymatic cleavage and prevents peptide cleavage by enzymes.
    [DAla2, DArg6] Dynorphin A, (1-13) (porcine)
  • HY-P3633
    Locustatachykinin II 126985-98-6 98%
    Locustatachykinin II (Lom-TK II) is an insect neuropeptide with homology to peptides of the vertebrate tachykinin family. Locustatachykinin II can be used for the research of insect endocrine.
    Locustatachykinin II
  • HY-P3634
    [DAla2] Dynorphin A (1-13), amide (porcine) 79985-43-6 98%
    [DAla2] Dynorphin A (1-13), amide (porcine) is a petide. [DAla2] Dynorphin A (1-13), amide (porcine) might have the κ opioid receptor agonist effect. [DAla2] Dynorphin A (1-13), amide (porcine) can be used for the research of nervous system.
    [DAla2] Dynorphin A (1-13), amide (porcine)
  • HY-P3635
    Cockroach Myoactive Peptide II 93240-39-2 98%
    Cockroach Myoactive Peptide II (Pea-CAH-II) is a cockroach neuropeptide. Cockroach Myoactive Peptide II is a member of the adipokinetic hormone/red pigment concentrating hormone (AKH/RPCH) family. Cockroach Myoactive Peptide II can be used for the research of metabolic functions of insect body.
    Cockroach Myoactive Peptide II
  • HY-P3636
    Cockroach Myoactive Peptide I 93208-51-6 98%
    Cockroach Myoactive Peptide I (Pea-CAH-I) is a cockroach neuropeptide, a member of the adipokinetic hormone/red pigment-concentrating hormone family (AKH/RPCH family).
    Cockroach Myoactive Peptide I
Cat. No. Product Name / Synonyms Application Reactivity