1. Inflammation/Immunology

Inflammation/Immunology

The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-B1374S2
    Florfenicol-13C6 98%
    Florfenicol-13C6 (SCH-25298-13C6) is 13C labeled Florfenicol. Florfenicol ((-)-Florfenicol) is an orally active broad-spectrum antibacterial antibiotic with anti-inflammatory, pro apoptotic, and immunomodulatory functions.
    Florfenicol-13C6
  • HY-B1390BR
    Saccharin sodium hydrate (Standard) 82385-42-0
    Saccharin (sodium hydrate) (Standard) is the analytical standard of Saccharin (sodium hydrate). This product is intended for research and analytical applications. Saccharin sodium hydrate is an orally active, non-caloric artificial sweeteners (NAS). Saccharin sodium hydrate has bacteriostatic and microbiome-modulating properties.
    Saccharin sodium hydrate (Standard)
  • HY-B1456AR
    Fenoprofen (Standard) 29679-58-1
    Fenoprofen (Standard) (LILLY-53858 (Standard)) is the analytical standard of Fenoprofen (HY-B1456A). This product is intended for research and analytical applications. Fenoprofenc is a nonsteroidal anti-inflammatory agent (NSAID) and inhibits cyclooxygenase (COX). Fenoprofen is a melanocortin receptors (MCRs) positive allosteric modulator (PAM). Fenoprofen also increases ERK1/2 activation in HEK293T cells. Fenoprofen has anti-arthritic activities and can be used for the study of rheumatoid arthritis and osteoarthritis.
    Fenoprofen (Standard)
  • HY-B1462S2
    Chlorzoxazone-13C,15N,d2 98%
    Chlorzoxazone-13C,15N,d2 is 13C-, 15N-, and deuterium-labeled Chlorzoxazone (HY-B1462).
    Chlorzoxazone-13C,15N,d2
  • HY-B1490AS
    Imipramine-d6 65100-45-0 98%
    Imipramine-d6 is the deuterium labeled Imipramine hydrochloride. Imipramine is an orally active tertiary amine tricyclic antidepressant. Imipramine is a Fascin1 inhibitor with antitumor activities. Imipramine also inhibits serotonin transporter with an IC50 value of 32 nM. Imipramine stimulates U-87MG glioma cells autophagy and induces HL-60 cell apoptosis. Imipramine shows neuroprotective and immunomodulatory effects.
    Imipramine-d6
  • HY-B1568AR
    Bromodiphenhydramine hydrochloride (Standard) 1808-12-4
    Bromodiphenhydramine (hydrochloride) (Standard) is the analytical standard of Bromodiphenhydramine (hydrochloride). This product is intended for research and analytical applications. Bromodiphenhydramine hydrochloride is a potent antihistamine with antimicrobial property. Bromodiphenhydramine hydrochloride inhibits a large number of Gram negative and Gram positive bacteria. Bromodiphenhydramine hydrochloride can be used for cutaneous allergies research.
    Bromodiphenhydramine hydrochloride (Standard)
  • HY-B1675AR
    Levalbuterol hydrochloride (Standard) 50293-90-8
    Levalbuterol (hydrochloride) (Standard) is the analytical standard of Levalbuterol (hydrochloride). This product is intended for research and analytical applications. Levalbuterol ((R)-Albuterol) hydrochloride is a short-acting β2-adrenergic receptor agonist and the active (R)-enantiomer of Salbutamol. Levalbuterol hydrochloride is a more potent bronchodilator than Salbutamol and has the potential for the treatment of COPD.
    Levalbuterol hydrochloride (Standard)
  • HY-B1788S2
    Taurocholic acid-d5 2044276-13-1 98%
    Taurocholic acid-d5 (Taurocholic Acid-d5) is deuterium labeled Taurocholic acid. Taurocholic acid (N-Choloyltaurine) has marked bioactive effects such as an inhibitory potential against hepatic artery ligation induced biliary damage by upregulation of VEGF-A expression. Taurocholic acid has immunoregulation effect.
    Taurocholic acid-d5
  • HY-B1831AR
    Oritavancin diphosphate (Standard) 192564-14-0
    Oritavancin (diphosphate) (Standard) is the analytical standard of Oritavancin (diphosphate). Oritavancin diphosphate (Standard), a semisynthetic derivative of Vancomycin (HY-B0671), is an orally active glycopeptide antibiotic with bactericidal activity against gram-positive organisms. Oritavancin diphosphate (Standard) shows antibacterial effect against B. anthracis, such as Ames strain with a MIC value of 0.015 g/mL. Oritavancin diphosphate (Standard) inhibits cell wall synthesis and disrupts the membrane potential. Oritavancin diphosphate (Standard) inhibits ArlS kinase activity thereby interfering the signal transduction. Oritavancin diphosphate (Standard) enters cells by adsorptive endocytosis, which drives it to lysosomes, where it exerts antibiotic activity.
    Oritavancin diphosphate (Standard)
  • HY-B1892S1
    Cefazolin-13C2,15N 2101505-58-0 98%
    Cefazolin-13C2,15N (Cephazolin-13C2,15N) is 13C and 15N labeled Cefazolin. Cefazolin (Cephazolin) is a first-generation cephalosporin antibiotic and can be used in varieties of bacterial infections research. Cefazolin has anti-inflammatory effect and can attenuate post-operative cognitive dysfunction (POCD).
    Cefazolin-13C2,15N
  • HY-B1895S1
    Levodropropizine-d5 98%
    Levodropropizine-d5 ((S)-(-)-Dropropizine-d5) is deuterium labeled Levodropropizine. Levodropropizine (DF-526) is an orally active histamine receptor inhibitor, Levodropropizine is an effective and very well tolerated peripheral antitussive agent.
    Levodropropizine-d5
  • HY-B1971S1
    Deltamethrin-d6 2483831-10-1 98%
    Deltamethrin-d6 (Decamethrin-d6) is deuterium labeled Deltamethrin. Deltamethrin (Decamethrin) is an orally active synthetic pyrethroid insecticide. Deltamethrin induces oxidative stress and results in inflammation and apoptosis via inhibiting Nrf2/HO-1 pathway. Deltamethrin has an anticancer effect by inducing apoptosis. Deltamethrin can be used extensively in pest control.
    Deltamethrin-d6
  • HY-B2130S2
    Uric acid-13C5 98%
    Uric acid-13C5 is the 13C-labeled Uric acid (HY-B2130). Radioactive isotopes labeled compounds can be used in metabolic analysis, allowing the movement of individual atoms to be precisely tracked and quantified.
    Uric acid-13C5
  • HY-D0205AR
    Carbocisteine (Standard) 638-23-3
    Carbocisteine (Standard) is the analytical standard of Carbocisteine. This product is intended for research and analytical applications. Carbocisteine, a mucolytic agent, can be used for the research of chronic obstructive pulmonary disease (COPD).
    Carbocisteine (Standard)
  • HY-D1056B4
    Lipopolysaccharides, from Salmonella typhosa 98%
    Lipopolysaccharides, from Salmonella typhosa are lipopolysaccharide endotoxins and TLR-4 activators derived from Salmonella typhosa, classified as S-type LPS, which can activate pathogen-associated molecular patterns (PAMP) of the immune system and induce cellular secretion of migrasomes. Lipopolysaccharides, from Salmonella typhosa exhibit a typical three-part structure: O-antigen, core oligosaccharide, and lipid A. Lipopolysaccharides, from Salmonella typhosa can serve as vaccine adjuvants and demonstrate adjuvant activity targeting B cells in immune responses in vivo.
    Lipopolysaccharides, from Salmonella typhosa
  • HY-I0447AR
    Sodium 4-aminosalicylate dihydrate (Standard) 6018-19-5
    Sodium 4-aminosalicylate (dihydrate) (Standard) is the analytical standard of Sodium 4-aminosalicylate (dihydrate). This product is intended for research and analytical applications. Sodium 4-aminosalicylate dihydrate (4-Aminosalicylic acid sodium salt dihydrate) is an inhibitor for dihydrofolate reductase (DHFR) and an antituberculous agent. Sodium 4-aminosalicylate dihydrate exhibits anti-inflammatory activity and can be used in research of inflammatory bowel disease (IBD). Sodium 4-aminosalicylate dihydrate is orally active.
    Sodium 4-aminosalicylate dihydrate (Standard)
  • HY-N0001S2
    (-)-Epicatechin-13C3 98%
    (-)-Epicatechin-13C3 ((-)-Epicatechol-13C3) is 13C labeled (-)-Epicatechin. (-)-Epicatechin inhibits cyclooxygenase-1 (COX-1) with an IC50 of 3.2 μM. (-)-Epicatechin inhibits the IL-1β-induced expression of iNOS by blocking the nuclear localization of the p65 subunit of NF-κB.
    (-)-Epicatechin-13C3
  • HY-N0092S4
    Inosine-13C3 98%
    Inosine-13C3 is a 13C-labeled Inosine that can be used in pharmacokinetic studies of Inosine. Inosine is an agonist of adenosine receptors A1R and A2AR with anti-inflammatory immunomodulatory, antinociceptive and neuroprotective effects.
    Inosine-13C3
  • HY-N0105S2
    Rhein-13C4 1189928-10-6 98%
    Rhein-13C4 (Rheic Acid-13C4) is 13C labeled Rhein. Rhein is an anthraquinone compound with anti-inflammatory, antioxidant, and anti-cancer effects.
    Rhein-13C4
  • HY-N0264S1
    Ligustrazine-d12 65127-74-4 98%
    Ligustrazine-d12 (Chuanxiongzine-d12) is deuterium labeled Ligustrazine. Ligustrazine (Chuanxiongzine), an alkylpyrazine isolated from Ligusticum chuanxiong Hort. (Chuan Xiong), is present in french fries, bread, cooked meats, tea, cocoa, coffee, beer, spirits, peanuts, filberts, dairy products and soy products as fragrance and flavouring ingredienexhibits. Ligustrazine also has potential nootropic and anti-inflammatory activities in rats.
    Ligustrazine-d12
Cat. No. Product Name / Synonyms Application Reactivity