2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

Related Products

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N15496
    Fusaproliferin 152469-17-5 98%
    Fusaproliferin is a sesterterpene mycotoxin isolated from Fusarium solani. Fusaproliferin reverse Lipopolysaccharides (HY-D1056) stimulation and the NF-κB and MAPKs signaling pathways contribute to the anti-inflammatory process. Fusaproliferin exhibits affinity for the TLR4 protein with KD values of 28.6 μM. Fusaproliferin shows cytotoxicity against pancreatic cancer cell with rapid and sub-micromolar IC50.
    Fusaproliferin
  • HY-N15564
    Theleganbanin B 31554-34-4 98%
    Theleganbanin B is a p-terphenyl derivative found in the Thelephora ganbajun. Theleganbanin B inhibits TNF-α, IL-6, and IL-1β production in LPS-induced BV-2 microglial cells. Theleganbanin B inhibits the phosphorylation of JAK2/STAT3. Theleganbanin B is promising for research of neurodegenerative diseases .
    Theleganbanin B
  • HY-N15565
    Theleganbanin C 98%
    Theleganbanin C is a p-terphenyl derivative found in the Thelephora ganbajun. Theleganbanin C is promising for research of neurodegenerative diseases .
    Theleganbanin C
  • HY-N15566
    Theleganbanin D 98%
    Theleganbanin D is a p-terphenyl derivative found in the Thelephora ganbajun. Theleganbanin D inhibits TNF-α, IL-6, and IL-1β production in LPS-induced BV-2 microglial cells. Theleganbanin D is promising for research of neurodegenerative diseases .
    Theleganbanin D
  • HY-N15569
    Fendleryl B 2098405-74-2 98%
    Fendleryl B is a compound isolated from the extract of the edible mushroom Gambas edible mushroom. Fendleryl B can be used in the study of neurological diseases.
    Fendleryl B
  • HY-N15571
    Hedopeptolide 98%
    Hedopeptolide can be found in the marine cyanobacteria Okeania sp. Hedopeptolide inhibits LSP-induced NO production in RAW264.7 cells (IC50: 4 μM). Hedopeptolide exhibits anti-inflammatory activity.
    Hedopeptolide
  • HY-N1570R
    Pterosin B (Standard) 34175-96-7
    Pterosin B (Standard) is the analytical standard of Pterosin B (HY-N1570). This product is intended for research and analytical applications. Pterosin B is an indanone. Pterosin B can be obtained from Pteridium aquilinum. Pterosin B is a Sik3 signaling inhibitor. Pterosin B inhibits Klf5 expression and reduces β-amyloid deposition. Pterosin B prevents chondrocyte hypertrophy and osteoarthritis in mice. Pterosin B inhibits cardiomyocyte hypertrophy, improves cognitive impairment, and lowers blood glucose. Pterosin B can be used in research on arthritis, Alzheimer's disease, pathological cardiac hypertrophy and diabetes.
    Pterosin B (Standard)
  • HY-N1949R
    Homoplantaginin (Standard) 17680-84-1
    Homoplantaginin (Standard) is the analytical standard of Homoplantaginin. This product is intended for research and analytical applications. Homoplantaginin is a flavonoid from a traditional Chinese medicine Salvia plebeia with antiinflammatory and antioxidant properties. Homoplantaginin could inhibit TNF-α and IL-6 mRNA expression, IKKβ and NF-κB phosphorylation.
    Homoplantaginin (Standard)
  • HY-N1965R
    Gaultherin (Standard) 490-67-5
    Gaultherin (Standard) is the analytical standard of Gaultherin. This product is intended for research and analytical applications. Gaultherin, a natural salicylate derivative, is isolated from Gaultheria yunnanensis. Gaultherin is a non-steroidal anti-inflammatory drug (NSAID). Gaultherin has analgesic and anti-inflammatory effects and lack gastric ulcerogenic effect compared to Aspirin.
    Gaultherin (Standard)
  • HY-N1973R
    Sennoside D (Standard) 37271-17-3
    Sennoside D (Standard) is the analytical standard of Sennoside D. This product is intended for research and analytical applications. Sennoside D is an anthraquinone glycoside, found in leaves and pods of Senna (Cassia angustifolia).
    Sennoside D (Standard)
  • HY-N1980R
    3'-Hydroxypuerarin (Standard) 117060-54-5
    3'-Hydroxypuerarin (Standard) is the analytical standard of 3'-Hydroxypuerarin. This product is intended for research and analytical applications. 3'-Hydroxypuerarin is an isoflavone isolated from the roots of Pueraria lobata (Willd.) Ohwi. 3'-Hydroxypuerarin is a antioxidant, which shows marked ONOO(-), NO?, total ROS scavenging activities.
    3'-Hydroxypuerarin (Standard)
  • HY-N1996R
    Chebulagic acid (Standard) 23094-71-5
    Chebulagic acid (Standard) is the analytical standard of Chebulagic acid. This product is intended for research and analytical applications. Chebulagic acid is a COX-LOX dual inhibitor isolated from the fruits of Terminalia chebula Retz, on angiogenesis. Chebulagic acid is a M2 serine to asparagine 31 mutation (S31N) inhibitor and influenza antiviral. Chebulagic acid also against SARS-CoV-2 viral replication with an EC50 of 9.76 μM.
    Chebulagic acid (Standard)
  • HY-N2006R
    Ganoderic acid B (Standard) 81907-61-1
    Ganoderic acid B (Standard) is the analytical standard of Ganoderic acid B. This product is intended for research and analytical applications. Ganoderic acid B is a triterpene isolated from a mushroom Ganoderma lucidum. Ganoderic acid B inhibits the activation of Epstein-Barr virus (EBV) antigens as telomerase inhibitor. Ganoderic acid B is a moderately active inhibitor against HIV-1 protease (IC50: 170 μM).
    Ganoderic acid B (Standard)
  • HY-N2007R
    Veratric acid (Standard) 93-07-2
    Veratric acid (Standard) is the analytical standard of Veratric acid. This product is intended for research and analytical applications. Veratric acid (3,4-Dimethoxybenzoic acid) is an orally active phenolic compound derived from vegetables and fruits, has antioxidant and anti-inflammatory activities. Veratric acid also acts as a protective agent against hypertension-associated cardiovascular remodelling. Veratric acid reduces upregulated COX-2 expression, and levels of PGE2, IL-6 after UVB irradiation.
    Veratric acid (Standard)
  • HY-N2013R
    Aristolactam I (Standard) 13395-02-3
    Aristolactam I (Standard) is the analytical standard of Aristolactam I. This product is intended for research and analytical applications. Aristolactam I is an AQP1 inhibitor and Aristolochic acid I metabolite. Aristolactam I can be isolated from Aristolochia plants. Aristolactam I downregulates Twist1 expression, increases E-cadherin expression, and activates the TGF-β/Smad signaling pathway. Aristolactam I has anticancer activity against breast cancer. Aristolactam I is nephrotoxic. Aristolactam I is mainly used in the study of breast cancer and kidney diseases such as renal interstitial fibrosis.
    Aristolactam I (Standard)
  • HY-N2014R
    Verbenalin (Standard) 548-37-8
    Verbenalin (Standard) is the analytical standard of Verbenalin. This product is intended for research and analytical applications. Verbenalin is an orally active terpenoid glycoside that can be extracted from the medicinal plant Verbena officinalis. Verbenalin has anti-inflammatory, antiviral, and neuroprotective effects. Verbenalin has a strong binding affinity to the nsp-12 protein of the SARS-CoV-2 virus. Verbenalin can be used in the research of inflammatory and nervous system diseases such as hepatitis and Alzheimer's disease.
    Verbenalin (Standard)
  • HY-N2035R
    Moslosooflavone (Standard) 3570-62-5
    Moslosooflavone (Standard) is the analytical standard of Moslosooflavone. This product is intended for research and analytical applications. Moslosooflavone is a flavonoid isolated from Andrographis paniculata. Moslosooflavone has an anti-hypoxia and anti-inflammatory activities.
    Moslosooflavone (Standard)
  • HY-N2065R
    Withaferin A (Standard) 5119-48-2
    Withaferin A (Standard) is the analytical standard of Withaferin A. This product is intended for research and analytical applications. Withaferin A is a steroidal lactone isolated from Withania somnifera, inhibits NF-kB activation and targets vimentin, with potent antiinflammatory and anticancer activities. Withaferin A is an inhibitor of endothelial protein C receptor (EPCR) shedding.
    Withaferin A (Standard)
  • HY-N2067R
    Vanillyl alcohol (Standard) 498-00-0
    Vanillyl alcohol (Standard) is the analytical standard of Vanillyl alcohol (HY-N2067). This product is intended for research and analytical applications. Vanillyl alcohol (p-(Hydroxymethyl)guaiacol) is an orally active phenolic alcohol. Vanillyl alcohol reduces ROS generation. suppresses Bax, increases Bcl-2. Vanillyl alcohol has anti-angiogenic, anti-inflammatory, anti-nociceptive and neuroprotective effects. Vanillyl alcohol is used as a flavoring agent in foods and beverages.
    Vanillyl alcohol (Standard)
  • HY-N2075R
    3-Acetyl-beta-boswellic acid (Standard) 5968-70-7
    3-Acetyl-beta-boswellic acid (Standard) is the analytical standard of 3-Acetyl-beta-boswellic acid. This product is intended for research and analytical applications. 3-Acetyl-beta-boswellic acid is a boswellic acid isolated from Boswellia serrata gum resin.
    3-Acetyl-beta-boswellic acid (Standard)
Cat. No. Product Name / Synonyms Application Reactivity