2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

Related Products

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N13301
    Aloe vera 85507-69-3 98%
    Aloe vera is an herbal plant known for its anti-inflammatory, antibacterial, anticancer, antioxidant, heart-protective, and wound-healing properties. Aloe vera can be used in research for tumors, diabetes, bone diseases, and cardiovascular diseases.
    Aloe vera
  • HY-N1346R
    Robinin (Standard) 301-19-9
    Robinin (Standard) is the analytical standard of Robinin. This product is intended for research and analytical applications. Robinin is a flavonoid that can be extracted from the leaves of purple cowpea, inhibiting TGF-β, TLR4/NF-κB and TLR2-PI3k-AKT signaling pathways. Robinin exerts anti-inflammatory and anti-tumor effects. The combination of Robinin and Methotrexate (HY-14519) reduces inflammation in experimental arthritis, Robinin can decrease the Doxorubicin (HY-15142A) induced cardiac toxicity effect.
    Robinin (Standard)
  • HY-N13701
    3β,7β,15α-Trihydroxy-4-(hydroxymethyl)-11,23-dioxo-lanost-8-en-26-oic acid 1961358-03-1 98%
    3β,7β,15α-Trihydroxy-4-(hydroxymethyl)-11,23-dioxo-lanost-8-en-26-oic acid is a triterpene compound that can be found in Ganoderma lucidum, and it inhibits nitric oxide (NO) production in BV-2 microglial cells induced by lipopolysaccharide (LPS, HY-D1056), with an IC50 of 4.15 μM.
    3β,7β,15α-Trihydroxy-4-(hydroxymethyl)-11,23-dioxo-lanost-8-en-26-oic acid
  • HY-N13706
    3β,15α-Dihydroxy-7,11,23-trioxo-lanost-8-dien-26-oic acid 117354-72-0 98%
    3β,15α-Dihydroxy-7,11,23-trioxo-lanost-8-dien-26-oic acid is a triterpene compound that can be found in Ganoderma lucidum, and it inhibits nitric oxide (NO) production in BV-2 microglial cells induced by lipopolysaccharide (LPS, HY-D1056), with an IC50 of 6.50 μM, making it a potential candidate for anti-inflammatory research.
    3β,15α-Dihydroxy-7,11,23-trioxo-lanost-8-dien-26-oic acid
  • HY-N13708
    4'-Methoxy-5,6-dihydroxyisoflavone-7-O-β-D-glucopyranoside 959960-45-3 98%
    4'-Methoxy-5,6-dihydroxyisoflavone-7-O-β-D-glucopyranoside is an isoflavonoid compound found in the rhizomes of Belamcanda chinensis with anti-inflammatory activity.
    4'-Methoxy-5,6-dihydroxyisoflavone-7-O-β-D-glucopyranoside
  • HY-N1374R
    Magnolin (Standard) 31008-18-1
    Magnolin (Standard) is the analytical standard of Magnolin. This product is intended for research and analytical applications. Magnolin, a major component of Magnolia liliiflora, inhibits the Ras/ERKs/RSK2 signaling axis by targeting the active pocket of ERK1 and ERK2 with IC50s of 87 nM and 16.5 nM, respectively.
    Magnolin (Standard)
  • HY-N13847
    Uralsaponin B 105038-43-5
    Uralsaponin B is classified as an oleanane-type triterpenoid saponin. Uralsaponin B exhibits potential anti-inflammatory and anti-infective activities.
    Uralsaponin B
  • HY-N13869
    Asperlin 30387-51-0 98%
    Asperlin is an orally active marine-derived antibiotic with antifungal, anticancer, anti-inflammatory and anti-atherosclerotic activities. Asperlin induces apoptosis. Asperlin increases reactive oxygen species (ROS)- and DNA damage-associated G2/M phase arrest and ATM phosphorylation. Asperlin is effective in preventing HFD-induced obesity and modulating gut microbiota.
    Asperlin
  • HY-N1388R
    Tussilagone (Standard) 104012-37-5
    Tussilagone (Standard) is the analytical standard of Tussilagone. This product is intended for research and analytical applications. Tussilagone, a major active component in Tussilago farfara, has anti-inflammatory effect. Tussilagone ameliorates inflammatory responses in dextran sulphate sodium-induced murine colitis. Tussilagone inhibits the inflammatory response and improves survival in cecal ligation and puncture (CLP)-induced septic mice.
    Tussilagone (Standard)
  • HY-N1399R
    Androsin (Standard) 531-28-2
    Androsin (Standard) is the analytical standard of Androsin. This product is intended for research and analytical applications. Androsin is an active compound isolated from Picrorhiza Kurroa Royle ex Benth. Androsin activates AMPKα/PI3K/Beclin1/LC3 signaling pathway, inhibits SREBP1c/FASN signaling pathway. Androsin can be used in research of asthma and non-alcoholic fatty liver disease (NAFLD). Androsin is orally active.
    Androsin (Standard)
  • HY-N1407R
    Polygalaxanthone III (Standard) 162857-78-5
    Polygalaxanthone III (Standard) is the analytical standard of Polygalaxanthone III. This product is intended for research and analytical applications. Polygalaxanthone III is extracted from polygala tenuifolia wild, has inhibitory effect towards CYP450 enzyme. Polygalaxanthone III inhibits chlorzoxazone 6-hydroxylation catalyzed by CYP2E1 with an IC50 of 50.56 μM.
    Polygalaxanthone III (Standard)
  • HY-N14152
    Desertomycin B 143629-44-1 98%
    Desertomycin B, the guanidino form of the antibiotic, is a minor fermentation product of Streptomyces flavofungi.
    Desertomycin B
  • HY-N14160
    Diaporthin 10532-39-5 98%
    Diaporthin is a phytotoxin that can be isolated from Cryphonectria parasitica. Diaporthin possesses antimicrobial activity in bacteria.
    Diaporthin
  • HY-N14162
    Dihydroabikoviromycin 38704-36-8 98%
    Dihydroabikoviromycin, a secondary metabolite of Streptomyces anulatus, is a polyketide synthase inhibitor.
    Dihydroabikoviromycin
  • HY-N14193
    Estatin B 106396-24-1 98%
    Estatin B is a thiol protease inhibitor found by the Thermophilic Bacterium M4323, which is specific to thiol proteases such as papain, fig protease, and bromelain. Estatin B inhibits the production of IgE antibodies but not IgG in mice.
    Estatin B
  • HY-N1422R
    Hecogenin (Standard) 467-55-0
    Hecogenin (Standard) is the analytical standard of Hecogenin. This product is intended for research and analytical applications. Hecogenin is a steroid saponin isolated from Agave sisalana and is a selective inhibitor of human UDP-glucuronosyltransferases. Hecogenin has a wide spectrum of pharmacological activities, including anti-inflammatory, antifungal and gastroprotective effects.
    Hecogenin (Standard)
  • HY-N14230
    Everninomicin D 39340-46-0 98%
    Everninomicin D is an antibiotic that is highly active against Gram-positive bacteria.
    Everninomicin D
  • HY-N14237
    Epoxyquinomicin A 175448-31-4 98%
    Epoxyquinomicin A is an antibiotic that can be isolated from Amycolatopsis sp. Epoxyquinomicin A exhibits inhibitory activity against Micrococcus luteus, Bacillus subtilis, Pasteurella piscicida and Staphylococcus aureus with a MIC of 3-12.5 µg/mL. Epoxyquinomicin A exhibits cytotoxicity in cancer cell L1210, B16 and S180 with IC50 of 2-8 µg/mL. Epoxyquinomicin A exhibits anti-inflammatory effects against collagen-induced arthritis.
    Epoxyquinomicin A
  • HY-N14238
    Epoxyquinomicin B 175448-32-5 98%
    Epoxyquinomicin B is an antibiotic that can be isolated from Amycolatopsis sp. Epoxyquinomicin B exhibits inhibitory activity against Micrococcus luteus, Bacillus subtilis, Pasteurella piscicida and Staphylococcus aureus with a MIC of 6.25-12.5 µg/mL. Epoxyquinomicin B exhibits cytotoxicity in cancer cell L1210 with IC50 of 16.3 µg/mL. Epoxyquinomicin B exhibits anti-inflammatory effects against collagen-induced arthritis.
    Epoxyquinomicin B
  • HY-N14246
    Exfoliamycin 148084-37-1 98%
    Exfoliamycin is a naphthoquinone antibiotic found by Streptomyces Exfoliamycin Tu 1424 and is active against Gram-positive bacteria.
    Exfoliamycin
Cat. No. Product Name / Synonyms Application Reactivity