2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N12344
    n-Butyl α-D-fructofuranoside 80971-59-1 98%
    n-Butyl α-D-fructofuranoside, isolated from the root barks of Ulmus davidiana var. japonica, enhances Nrf2 activity through activation of JNK and has antiinflammation activity.
    n-Butyl α-D-fructofuranoside
  • HY-N12473
    25-Deacetylcucurbitacin A 1135141-77-3 98%
    25-Deacetylcucurbitacin A is a Cucurbitane-Type triterpenoid and has the potential to be an anti-cancer agent and JAK/STAT3 signaling pathway inhibitor.
    25-Deacetylcucurbitacin A
  • HY-N12481
    Cephalandole B 915315-44-5 98%
    Cephalandole B is an indigo alkaloid that has the activity of inhibiting IL-17A gene expression. Cephalandole B significantly inhibited the activity of IL-17A luciferase reporter gene in Jukat cells, and this inhibitory effect was dose-dependent. Cephalandole B may have important application prospects in inflammation-related research.
    Cephalandole B
  • HY-N12482
    Callicarboric acid A 98%
    NLRP3-IN-27 (compound 1) is an inhibitor of NLRP3 with an IC50 value of 0.74 μM. NLRP3 reduces inflammasome-induced pyroptosis in J774A.1 cells. NLRP3-IN-27 can be isolated from Callicarpa arborea Rox.
    Callicarboric acid A
  • HY-N12494
    Diplacol 76556-05-3 98%
    Diplacol is a geranylated flavanone that can be isolated from paulownia trees (Paulownia coreana UYEKI). Diplacol has anti-inflammatory activity. Diplacol inhibits NO production in LPS-stimulated Raw264.7 cells with an IC50 value of 4.53 μM.
    Diplacol
  • HY-N12512
    6-O-p-Coumaroyl scandoside methyl ester 83946-90-1 98%
    6-O-p-Coumaroyl scandoside methyl ester is a compound that can be isolated from oldenlandia diffusa. 6-O-p-Coumaroyl scandoside methyl ester has anti-inflammatory activity.
    6-O-p-Coumaroyl scandoside methyl ester
  • HY-N12579
    Desacylsenegasaponin B 163589-51-3 98%
    Desacylsenegasaponin B is an active product that can be extracted from? root of Polygala tenuifolia. Desacylsenegasaponin B has potential anti-inflammatory activity.
    Desacylsenegasaponin B
  • HY-N12587
    Platycoside F 314756-03-1 98%
    Platycoside F is a triterpenoid saponin compound that can be isolated from the roots of Platycodon grandiflorum .
    Platycoside F
  • HY-N12609
    3β-Isodihydrocadambine 62014-69-1 98%
    3β-Isodihydrocadambine, a derivative of cadambine, is obtained from the bark and leaves of Neolamarckia cadamba and possesses notable antimalarial, antiproliferative, antioxidant, anticancer, and anti-inflammatory properties.
    3β-Isodihydrocadambine
  • HY-N12693
    Isobiflorin 152041-16-2 98%
    Isobiflorin is an anti-inflammatory agent and can be isolated from Syzygium aromaticum. Isobiflorin inhibits LPS-induced PGE2 production with an IC50 value of 46.0 μM.
    Isobiflorin
  • HY-N12783
    Digitoxigenin-3-O-β-D-quinovoside 40950-57-0 98%
    Digitoxigenin-3-O-β-D-quinovoside is an interleukin-2 (IL-2)/luciferase inhibitor with an IC50 value of 52 nM. Digitoxigenin-3-O-β-D-quinovoside is a cardiac lactone isolated from Elaeodendron australe var. integrifolium.
    Digitoxigenin-3-O-β-D-quinovoside
  • HY-N12855
    Mutabiloside 1073235-22-9 98%
    Mutabiloside is a natural product with anti-allergic activity. Mutabiloside can be used in the study of complex allergic reactions.
    Mutabiloside
  • HY-N12907
    4′-Oxomacrophorin A 349147-29-1 98%
    4′-Oxomacrophorin A is an immunosuppressant and can be isolated from Eupenicillium crustaceum.
    4′-Oxomacrophorin A
  • HY-N13098
    Elatoside F 144118-18-3 98%
    Elatoside F is a triterpenoid saponin with anti-inflammatory activity. Elatoside F inhibits lipopolysaccharide-induced nitric oxide production and nuclear factor NF-κB activation. Elatoside F can be isolated from Aralia elata in one step.
    Elatoside F
  • HY-N13153
    Antioxidant agent-19 146564-36-5 98%
    Antioxidant agent-19 (compound 12) is an arylbutyl glycoside with antioxidant activity that can be isolated from the bark of B. platyphylla vat. Japonica.
    Antioxidant agent-19
  • HY-N13159
    Goodyeroside A 211107-44-7 98%
    Goodyeroside A is a glycoside compound derived from the plant Goodyera that exhibits significant hepatoprotective activity. It can inhibit liver damage induced by carbon tetrachloride (HY-Y0298) in primary cultured rat hepatocytes.
    Goodyeroside A
  • HY-N13167
    3-Keto-tirucall-8,24-dien-21-oic acid 98%
    3-Keto-tirucall-8,24-dien-21-oic acid is a tetracyclic triterpene compound that can be isolated from frankincense. 3-Keto-tirucall-8,24-dien-21-oic acid has activities like anti-inflammatory, anti-tumor, anti-ulcer, memory improvement, and antioxidant properties.
    3-Keto-tirucall-8,24-dien-21-oic acid
  • HY-N13174
    Peanut procyanidin A 1802175-67-2 98%
    Peanut procyanidin A is a type of A-type procyanidin that can be extracted from peanut skins. Peanut procyanidin A can protect prostate DU145 cells from H2O2-induced oxidative stress damage through the MAPKs signaling pathway, alleviate cell cycle arrest, and reduce cell apoptosis. Peanut procyanidin A can also regulate gut microbiota and metabolism in mice with DSS (HY-116282)-induced ulcerative colitis.
    Peanut procyanidin A
  • HY-N13177
    25(S)Ruscogenin 3-O-α-L-rhamnopyranoside 1869126-66-8 98%
    25(S)Ruscogenin 3-O-α-L-rhamnopyranoside is from the fibrous roots of Ophiopogon japonicus and Liriope spicata var. prolifera. 25(S)Ruscogenin 3-O-α-L-rhamnopyranoside exhibits anti-inflammatory activity by inhibiting neutrophil responses to PMA (HY-18739), with an IC50 value of 1.13 μM.
    25(S)Ruscogenin 3-O-α-L-rhamnopyranoside
  • HY-N13202
    Black Currant Extract 98%
    Black Currant Extract is a black currant extract, and its components include: Anthocyanidins. Black Currant Extract is an anti-inflammatory agent that can neutralize the cytotoxic effects of nicotine on epithelial cells and fibroblasts in a dose-dependent manner. Black Currant Extract can also inhibit LPS-induced IL-6 secretion by human macrophages..
    Black Currant Extract
Cat. No. Product Name / Synonyms Application Reactivity