1. Inflammation/Immunology

Inflammation/Immunology

The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N1072R
    Wilforgine (Standard) 37239-47-7
    Wilforgine (Standard) is the analytical standard of Wilforgine. This product is intended for research and analytical applications. Wilforgine is a bioactive sesquiterpene alkaloid in Tripterygium wilfordii Hook. F. Wilforgine can induce microstructural and ultrastructural changes in the muscles of Mythimna separata larvae, and the sites of action are proposed to be calcium receptors or channels in the muscular system.
    Wilforgine (Standard)
  • HY-N10944
    Chrysoobtusin 2-β-D-glucoside 96820-54-1 98%
    Chrysoobtusin 2-β-D-glucoside is an anthraquinone glycoside found in Cassia obtusifolia. Chrysoobtusin 2-β-D-glucoside may have potential anti-inflammatory and antioxidant activities.
    Chrysoobtusin 2-β-D-glucoside
  • HY-N11699
    Bequinostatin A 151013-37-5 98%
    Bequinostatin A is a benzo[a]naphthacenequinone metabolite that can be isolated from Streptomyces sp. MI384-DF12. Bequinostatin A shows considerable inhibitory activity against human pi class glutathione S-transferase (GST pi).
    Bequinostatin A
  • HY-N1181R
    Tamarixetin (Standard) 603-61-2
    Tamarixetin (Standard) is the analytical standard of Tamarixetin. This product is intended for research and analytical applications. Tamarixetin (4'-O-Methyl Quercetin) is an orally active natural flavonoid derivative of quercetin and caseinolytic protease p (ClpP) inhibitor with anti-inflammatory, antioxidant and antitumor effects. Tamarixetin inhibits the hydrolytic activity of ClpP to the fluorescent substrate Suc-LY-AMC with an IC50 of 49.73 μM, which can be used for the study of Staphylococcus aureus infection. Tamarixetin inhibits tumor cell growth, induces apoptosis, and cell cycle arrest. Tamarixetin prevents cardiac hypertrophy by inhibiting the NFAT and AKT pathways.
    Tamarixetin (Standard)
  • HY-N11920
    Kadsurenin B 145701-13-9 98%
    Kadsurenin B is a PAF (platelet-activating factor) antagonist with neuroprotective activity. Kadsurenin B has a wide range of pharmacological research potential, such as antibacterial, anti-inflammatory, neuroprotective, antioxidant, antiplatelet aggregation, cytotoxic, antiparasitic, etc.
    Kadsurenin B
  • HY-N11929
    (S)-(+)-Imperanene 163634-08-0 98%
    (S)-(+)-Imperanene can be isolated from Imperata cylindrica. Imperata cylindrica has diuretic and antiinflammatory activity.
    (S)-(+)-Imperanene
  • HY-N11934
    Piperkadsin A 895543-36-9 98%
    Piperkadsin A is a potent inhibitor of ROS. Piperkadsin inhibits PMA-induced ROS production in human polymorphonuclear neutrophils with an IC50 of 4.3 μM.
    Piperkadsin A
  • HY-N11992
    Aloenin-2'-p-coumaroyl ester 106533-35-1 98%
    Aloenin-2'-p-coumaroyl ester is a natural product that can be obtained from the leaves of Aloe vera. Aloenin-2'-p-coumaroyl ester has the potential for the resesech of inflammation.
    Aloenin-2'-p-coumaroyl ester
  • HY-N11994
    Aloeresin G 287486-23-1 98%
    Aloeresin G is a chromone glycoside that can be isolated from Aloe. Aloeresin G has a weak inhibitory effect on TNFα-induced NF-κB transcriptional activity, with an IC 50 value of 40.02 μM.
    Aloeresin G
  • HY-N12010
    12-epi-Teucvidin 125137-19-1 98%
    12-epi-Teucvidin is a diterpenoid that can be obtained from Teucrium fourrifarium. 12-epi-Teucvidin has the potential for research of antioxidant, analgesic, and anti-inflammatory.
    12-epi-Teucvidin
  • HY-N12040
    γ-Isofagarine 569-02-8 98%
    γ-Isofagarine (Iso-γ-fagarine) is an alkaloid that can be isolated from the root bark of Dictamnus angustifolius. Dictamnus angustifolius has been used in the research of rheumatism, bleeding, itching, jaundice, chronic hepatitis, skin diseases, etc.
    γ-Isofagarine
  • HY-N12067
    Columbianetin β-D-glucopyranoside 55836-35-6 98%
    Columbianetin β-D-glucopyranoside can be isolated from Angelicae pubescentis radix and has antiplatelet aggregation, anti-inflammatory and analgesic activities. Columbianetin β-D-glucopyranoside exerts significant protective effects against glutamate-induced toxicity.
    Columbianetin β-D-glucopyranoside
  • HY-N12069
    Praeroside IV 117233-34-8 98%
    Praeroside IV can be isolated from the roots of Angelica furcijuga. Praeroside IV can be used for research of D-GalN/LPS-induced liver injury.
    Praeroside IV
  • HY-N12101
    Anti-inflammatory agent 57 440094-34-8 98%
    Anti-inflammatory agent 57 (Compound 13), pyranocoumarin, is a nature product. Anti-inflammatory agent 57 can be isolated from the roots of Peucedanum praeruptorum. Anti-inflammatory agent 57 has multidrug-resistance (MDR) reversal and anti-inflammatory effect.
    Anti-inflammatory agent 57
  • HY-N12141
    Flaccidoside II 140694-19-5 98%
    Flaccidoside II inhibits proliferation and induces apoptosis in Malignant peripheral nerve sheath tumors (MPNSTs) cell lines. Flaccidoside II ameliorates collagen-induced arthritis in mice. Flaccidoside II is an active triterpenoid saponin constituent from Anemone flaccida rhizome.
    Flaccidoside II
  • HY-N12176
    Euphenol 564-60-3 98%
    Euphenol (Dihydroeuphol) is a synthetic triterpene and a derivative of Euphol (HY-N0313).
    Euphenol
  • HY-N12224
    1-Heptadecanoyl-rac-glycerol 5638-14-2 98%
    1-Heptadecanoyl-rac-glycerol (1-Heptadecanoin) is a glyceride compound with anti-inflammatory activity. 1-Heptadecanoyl-rac-glycerol inhibits the occurrence of inflammation by suppressing the expression of inducible nitric oxide synthase (iNOS) related to inflammation. 1-Heptadecanoyl-rac-glycerol can be used for research on diseases related to inflammation.
    1-Heptadecanoyl-rac-glycerol
  • HY-N12261
    Benastatin B 138968-86-2 98%
    Benastatin B is an inhibitor for glutathione S-transferase, that inhibits human pi class GST with an IC50 of 1.10 μg/mL. Benastatin B exhibits board-spectrum antibacterial efficacy, inhibits MRSA with MIC 3.1 μg/mL. Benastatin B exhibits anti-inflammatory efficacy through inhibition of IgE mediated β-hexosaminidase release with an IC50 of 79 μg/mL.
    Benastatin B
  • HY-N12283
    NF-κB-IN-13 117596-92-6 98%
    NF-κB-IN-13 (compound 12) can significantly inhibit LPS-induced NF-κB activation and NO production in RAW264.7 macrophages. NF-κB-IN-13 has anti-inflammatory effects.
    NF-κB-IN-13
  • HY-N12344
    n-Butyl α-D-fructofuranoside 80971-59-1 98%
    n-Butyl α-D-fructofuranoside, isolated from the root barks of Ulmus davidiana var. japonica, enhances Nrf2 activity through activation of JNK and has antiinflammation activity.
    n-Butyl α-D-fructofuranoside
Cat. No. Product Name / Synonyms Application Reactivity