1. Inflammation/Immunology

Inflammation/Immunology

The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N0406R
    2"-O-beta-L-galactopyranosylorientin (Standard) 861691-37-4
    2"-O-beta-L-galactopyranosylorientin (Standard) is the analytical standard of 2"-O-beta-L-galactopyranosylorientin. This product is intended for research and analytical applications. 2"-O-beta-L-galactopyranosylorientin is extracted from the flowers of Trollius ledebouri. 2"-O-beta-L-galactopyranosylorientin involves transporter mediated efflux in addition to passive diffusion and is the substrate of multidrug resistance protein 2 (MRP2). Anti-inflammatory effect.
    2
  • HY-N0407R
    Picroside I (Standard) 27409-30-9
    Picroside I (Standard) is the analytical standard of Picroside I. This product is intended for research and analytical applications. Picroside I is the major ingredient of Picrorhiza scrophulariiflora. Picrorhiza scrophulariiflora is a high value medicinal herb due to rich source of hepatoprotective metabolites, Picroside-I and Picroside-II. Picroside I is a promising agent for the management of asthma. Picroside I reduces the inflammation significantly at its higher dose. Picroside I also downregulates pSTAT6 and GATA3 expressions. Picroside I dose-dependently increases the serum levels of IFN-γ.
    Picroside I (Standard)
  • HY-N0412R
    Sesamoside (Standard) 117479-87-5
    Sesamoside (Standard) is the analytical standard of Sesamoside. This product is intended for research and analytical applications. Sesamoside is a iridoid isolated from the aerial part of? Lamiophlomis rotata. Sesamoside has antiodant and antiglycation activities.
    Sesamoside (Standard)
  • HY-N0433R
    Astragaloside II (Standard) 84676-89-1
    Astragaloside II (Standard) is the analytical standard of Astragaloside II (HY-N0433). This product is intended for research and analytical applications. Astragaloside II is an orally active Cycloartane-type triterpene glycoside. Astragaloside II can be extracted from Astragalus membranaceus. Astragaloside II inhibits Autophagy, decreases pro-inflammatory cytokines (IL-6, IL-1β), HIF-α, p-p65, p-IκB and increases SOD. Astragaloside II regulates immunity and reduces inflammatory responses. Astragaloside II can be used in the research of diseases such as liver cancer, osteoporosis, immunosuppressive diseases, and ulcerative colitis.
    Astragaloside II (Standard)
  • HY-N0436R
    Engeletin (Standard) 572-31-6
    Engeletin (Standard) is the analytical standard of Engeletin. This product is intended for research and analytical applications. Engeletin is a flavanonol glycoside isolated from Smilax glabra Roxb. , inhibits NF-κB signaling-pathway activation, and possesses anti-inflammatory, analgesic, diuresis, detumescence, and antibiosis effects.
    Engeletin (Standard)
  • HY-N0440R
    Germacrone (Standard) 6902-91-6
    Germacrone (Standard) is an analytical standard of Gemmacrone (HY-N0440). This product is intended for research and analytical applications. Germacrone (Standard) is a sesquiterpene compound with multiple biological activities. Germacrone (Standard) inhibits the H1N1 and H3N2 influenza A viruses and the influenza B virus. Germacrone (Standard) blocks the progressionof arthritis by regulating Th1/Th2 balance and inhibiting NF-κB signaling. Germacrone (Standard) can arrest the cell cycle at G0/G1 and G2/M phases and induce apoptosis in breast cancer cells. Germacrone (Standard) inhibits 5α-reductase and has anti-androgenic effect. Germacrone (Standard) has neuroprotective functions and can be used for the study of traumatic brain injury (TBI). Germacrone (Standard) also has antioxidant activity.
    Germacrone (Standard)
  • HY-N0443R
    N-Methylcytisine (Standard) 486-86-2
    N-Methylcytisine (Standard) is the analytical standard of N-Methylcytisine. This product is intended for research and analytical applications. N-Methylcytisine (Caulophylline), a tricyclic quinolizidine alkaloid, exerts hypoglycaemic, analgesic and anti-inflammatory activities. N-methylcytisine is a selective ligand of nicotinic receptors of acetylcholine in the central nervous system and has a high affinity (Kd = 50 nM) to nicotinic acetylcholine receptors (nAChR) from squid optical ganglia.
    N-Methylcytisine (Standard)
  • HY-N0444R
    Rubiadin (Standard) 117-02-2
    Rubiadin (Standard) is the analytical standard of Rubiadin. This product is intended for research and analytical applications. Rubiadin is a dihydroxy anthraquinone isolated from Rubia cordifolia. Rubiadin has a potent antixidant activity.
    Rubiadin (Standard)
  • HY-N0469A
    L-Lysine (sulfite) 53411-64-6 98%
    L-lysine sulfite is an essential amino acid for humans, offers numerous benefits and can be used in herpes research. Additionally, L-lysine sulfite enhances calcium absorption, reduces diabetes-related complications, improves gut health, and alleviates pancreatitis inflammation.
    L-Lysine (sulfite)
  • HY-N0470R
    L-Lysine hydrochloride (Standard) 657-27-2
    L-Lysine hydrochloride (Standard) is the analytical standard of L-Lysine hydrochloride. This product is intended for research and analytical applications. L-lysine hydrochloride is an essential amino acid for humans with various benefits including treating herpes, increasing calcium absorption, reducing diabetes-related illnesses and improving gut health.
    L-Lysine hydrochloride (Standard)
  • HY-N0474R
    Tyrosol (Standard) 501-94-0
    Tyrosol (Standard) is the analytical standard of Tyrosol. This product is intended for research and analytical applications. Tyrosol is a derivative of phenethyl alcohol. Tyrosol attenuates pro-inflammatory cytokines from cultured astrocytes and NF-κB activation. Anti-oxidative and anti-inflammatory effects.
    Tyrosol (Standard)
  • HY-N0476R
    Wilforlide A (Standard) 84104-71-2
    Wilforlide A (Standard) is the analytical standard of Wilforlide A. This product is intended for research and analytical applications. Wilforlide A is a bioactive triterpene isolated from Tripterygium wilfordii Hook f. Wilforlide A has anti-inflammatory and immune suppressive effects.
    Wilforlide A (Standard)
  • HY-N0481R
    Roburic acid (Standard) 6812-81-3
    Roburic acid (Standard) is the analytical standard of Roburic acid. This product is intended for research and analytical applications. Roburic acid, a tetracyclic triterpenoid found in Gentiana macrophylla, acts as an inhibitor of COX, with IC50s of 5 and 9 μM for COX-1 and COX-2, respectively.
    Roburic acid (Standard)
  • HY-N0487R
    Glucosamine sulfate (Standard) 29031-19-4
    Glucosamine (sulfate) (Standard) is the analytical standard of Glucosamine (sulfate). This product is intended for research and analytical applications. Glucosamine sulfate (D-Glucosamine sulfate) is an amino sugar and a prominent precursor in the biochemical synthesis of glycosylated proteins and lipids, is used as a dietary supplement. Glucosamine sulfate also is a natural constituent of glycosaminoglycans in the cartilage matrix and synovial fluid, which when administered exogenously, exerts pharmacological effects on osteoarthritic cartilage and chondrocytes.
    Glucosamine sulfate (Standard)
  • HY-N0493R
    Pectolinarigenin (Standard) 520-12-7
    Pectolinarigenin (Standard) is the analytical standard of Pectolinarigenin. This product is intended for research and analytical applications. Pectolinarigenin is a dual inhibitor of COX-2/5-LOX. Anti-inflammatory activity. Pectolinarigenin has potent inhibitory activities on melanogenesis.
    Pectolinarigenin (Standard)
  • HY-N0494R
    Gentiopicroside (Standard) 20831-76-9
    Gentiopicroside (Standard) is the analytical standard of Gentiopicroside. This product is intended for research and analytical applications. Gentiopicroside, a naturally occurring iridoid glycoside, inhibits P450 activity, with an IC50 and a Ki of 61 μM and 22.8 μM for CYP2A6; Gentiopicroside has anti-inflammatoryand antioxidative effects.
    Gentiopicroside (Standard)
  • HY-N0508R
    Rosin (Standard) 85026-55-7
    Rosin (Standard) is the analytical standard of Rosin. This product is intended for research and analytical applications. Rosin is isolated from pine wood or pine stumps, Rosin is a frequent contact allergen which induces allergic contact dermatitis.
    Rosin (Standard)
  • HY-N0516R
    Casticin (Standard) 479-91-4
    Casticin (Standard) is the analytical standard of Casticin. This product is intended for research and analytical applications. Casticin is a methyoxylated flavonol isolated from Vitex rotundifolia, with antimitotic and anti-inflammatory effect. Casticin inhibits the activation of STAT3.
    Casticin (Standard)
  • HY-N0526R
    2"-O-Galloylhyperin (Standard) 53209-27-1
    2"-O-Galloylhyperin (Standard) is the analytical standard of 2"-O-Galloylhyperin. This product is intended for research and analytical applications. 2"-O-Galloylhyperin, an active compound isolated from Pyrola incarnate Fisch., possesses anti-oxidative and anti-inflammatory activities. 2"-O-Galloylhyperin has hepatoprotective effect against oxidative stress-induced liver damage.
    2
  • HY-N0534R
    Vitexin-2"-O-rhamnoside (Standard) 64820-99-1
    Vitexin-2"-O-rhamnoside (Standard) is the analytical standard of Vitexin-2"-O-rhamnoside (HY-N0534). This product is intended for research and analytical applications. Vitexin-2"-O-rhamnoside is an orally active flavonoid glycoside. Vitexin-2"-O-rhamnoside inhibits Apoptosis, increases the phosphorylation levels of PI3K/Akt, inhibits caspase-3, SOD activity, and promotes cytokine (IL-2, IL-6, and IL-12) secretion. Vitexin-2"-O-rhamnoside strongly inhibits DNA synthesis in MCF-7 cells with an IC50 of 17.5 μM. Vitexin-2"-O-rhamnoside enhances immune function and improves the absorption of active compounds. Vitexin-2"-O-rhamnoside has antioxidant activity. Vitexin-2"-O-rhamnoside is used in the study of cardiovascular disease and immune-related diseases.
    Vitexin-2
Cat. No. Product Name / Synonyms Application Reactivity