1. Inflammation/Immunology

Inflammation/Immunology

The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-19655S
    Cethromycin-d6 98%
    Cethromycin-d6 (ABT-773-d6; Abbott-195773-d6; A-195773-d6) is deuterium-labeled Cethromycin (HY-19655).
    Cethromycin-d6
  • HY-19657R
    Oxypurinol (Standard) 2465-59-0
    Oxypurinol (Standard) is the analytical standard of Oxypurinol. This product is intended for research and analytical applications. Oxipurinol (Oxipurinol), the major active metabolite of Allopurinol, is an inhibitor of xanthine oxidase. Oxipurinol can be used to regulate blood urate levels and treat gout.
    Oxypurinol (Standard)
  • HY-19883R
    Lusutrombopag (Standard) 1110766-97-6
    Lusutrombopag (Standard) is the analytical standard of Lusutrombopag. This product is intended for research and analytical applications. Lusutrombopag is an orally bioavailable thrombopoietin (TPO) receptor agonist, used for treatment of chronic liver disease.
    Lusutrombopag (Standard)
  • HY-24470B
    1-(9H-Fluoren-9-yl)ethanol 3023-49-2 98%
    1-(9H-Fluoren-9-yl)ethanol is a prominent fragment in β-lactam antibiotic modification and an important building block for anti-inflammatory agent.
    1-(9H-Fluoren-9-yl)ethanol
  • HY-30151R
    Methoxsalen (Standard) 298-81-7
    Methoxsalen (Standard) is the analytical standard of Methoxsalen. This product is intended for research and analytical applications. Methoxsalen (8-Methoxypsoralen) is a furanocoumarin compound used in psoralen, used in studies of psoriasis, eczema, vitiligo and some sun-exposed cutaneous lymphomas, and is a P450 inhibitor.
    Methoxsalen (Standard)
  • HY-30272R
    Monobenzone (Standard) 103-16-2
    Monobenzone (Standard) is the analytical standard of Monobenzone. This product is intended for research and analytical applications. Monobenzone is a potent skin depigmenting agent. Monobenzone induces depigmentation and active human vitiligo and exhibits good potential for vitiligo research.
    Monobenzone (Standard)
  • HY-32337R
    Tacalcitol (Standard) 57333-96-7
    Tacalcitol (Standard) is the analytical standard of Tacalcitol. This product is intended for research and analytical applications. Tacalcitol (1,24(R)-Dihydroxyvitamin D3; 1.alpha.,24R-Dihydroxyvitamin D3) can promote normal bone growth by regulating calcium ions. Tacalcitol inhibits cancer cell proliferation and migration. Tacalcitol can be used in the research of inflammation, cancer, and skin diseases.
    Tacalcitol (Standard)
  • HY-32343S
    Secalciferol-d6 1440957-55-0 98%
    Secalciferol-d6 is the deuterium labeled Secalciferol. Secalciferol is a metabolite of Vitamin D, a possibly anti-inflammatory steroid which is involved in bone ossification.
    Secalciferol-d6
  • HY-40354B
    (3S,4R)-Tofacitinib 1092578-48-7 98%
    (3S,4R)-Tofacitinib is an less active enantiomer of Tofacitinib. Tofacitinib inhibits JAK3 with IC50 of 1 nM.
    (3S,4R)-Tofacitinib
  • HY-40354R
    Tofacitinib (Standard) 477600-75-2
    Tofacitinib (Standard) is the analytical standard of Tofacitinib. This product is intended for research and analytical applications. Tofacitinib is an orally available JAK3/2/1 inhibitor with IC50s of 1, 20, and 112 nM, respectively.
    Tofacitinib (Standard)
  • HY-42034R
    Hydroquinine (Standard) 522-66-7
    Hydroquinine (Standard) is the analytical standard of Hydroquinine. This product is intended for research and analytical applications. Hydroquinine is a cinchona alkaloid, can be used in the preparation of its derivatives such as C9 epihydroquinine, 9-acetoxy-10,11-dihydroquinine and 10,11-dihydroquinine monohydrochloride.
    Hydroquinine (Standard)
  • HY-42682R
    D(+)-Galactosamine hydrochloride (Standard) 1772-03-8
    D(+)-Galactosamine (hydrochloride) (Standard) is the analytical standard of D(+)-Galactosamine (hydrochloride). This product is intended for research and analytical applications. D(+)-Galactosamine (D-Galactosamine) hydrochloride, which is an established experimental toxin, primarily causes liver injury by the generation of free radicals and depletion of UTP nucleotides. D(+)-Galactosamine hydrochloride intoxication also induces renal dysfunction thus, renal failure is often associated with the end-stage of the liver damage. Lipopolysaccharide/D(+)-Galactosamine-induced acute liver injury is a known animal model of fulminant hepatic failure.
    D(+)-Galactosamine hydrochloride (Standard)
  • HY-66009R
    Epalrestat (Standard) 82159-09-9
    Epalrestat (Standard) is the analytical standard of Epalrestat. This product is intended for research and analytical applications. Epalrestat is an orally active aldose reductase inhibitor that acts on diabetic neuropathy.
    Epalrestat (Standard)
  • HY-66012R
    Proparacaine Hydrochloride (Standard) 5875-06-9
    Proparacaine (Hydrochloride) (Standard) is the analytical standard of Proparacaine (Hydrochloride). This product is intended for research and analytical applications. Proparacaine Hydrochloride (Proxymetacaine Hydrochloride) is a derivative of lidocaine (HY-B0185), with immunomodulatory effect and glucocorticomimetic activity.
    Proparacaine Hydrochloride (Standard)
  • HY-70050B
    Alosetron ((Z)-2-butenedioate) 122852-43-1 98%
    Alosetron (GR 68755) (Z)-2-butenedioate is a potent and highly selective serotonin 5-HT3 receptor antagonist. Alosetron (Z)-2-butenedioate is used for the research of irritable bowel syndrome (IBS). Alosetron (Z)-2-butenedioate blocks the fast 5HT3-mediated depolarisation of guinea-pig myenteric and submucosal neurons, with IC50 at ~55 nM. Alosetron (Z)-2-butenedioate attenuates the visceral nociceptive effect of rectal distension in conscious or anaesthetised dogs. Anti-inflammatory effects.
    Alosetron ((Z)-2-butenedioate)
  • HY-75385A
    Zaurategrast ethyl ester sulfate 1214261-78-5 98%
    Zaurategrast ethyl ester sulfate (CDP323 sulfate), the ethyl ester proagent of CT7758, is a α4β1/α4β7 integrin antagonist used for the treatment of inflammatory and autoimmune disorders.
    Zaurategrast ethyl ester sulfate
  • HY-75424A
    2-(Trifluoromethyl)cinnamic acid 2062-25-1 99.77%
    2-(Trifluoromethyl)cinnamic acid is a cinnamic acid derivative that inhibits the proton pump (H+/K+-ATPase), thereby reducing gastric acid secretion. 2-(Trifluoromethyl)cinnamic acid also improves delayed gastric emptying and can be used in research on gastric diseases such as acute gastritis and gastric ulcers.
    2-(Trifluoromethyl)cinnamic acid
  • HY-76082A
    L-Pyroglutamic acid sodium 28874-51-3 98%
    L-Pyroglutamic acid sodium is the levo-isomer of Pyroglutamic acid. L-Pyroglutamic acid sodium is the biologically active enantiomer in humans. Pyroglutamic acid is an intermediate in glutathione metabolism. L-Pyroglutamic acid sodium can be used as a biomarker for systemic lupus erythematosus (SLE).
    L-Pyroglutamic acid sodium
  • HY-76251R
    Etodolac (Standard) 41340-25-4
    Etodolac (Standard) is the analytical standard of Etodolac. This product is intended for research and analytical applications. Etodolac (AY-24236) is a non-steroidal anti-inflammatory compound that is a non-selective inhibitor of COX (IC50=53.5 nM)
    Etodolac (Standard)
  • HY-76511S
    Verlukast-d6 153698-86-3 98%
    Verlukast-d6 is a deuterium labeled Verlukast. Verlukast is a potent, selective, and orally active antagonist of leukotriene receptor. Verlukast has the potential for the research of asthma.
    Verlukast-d6
Cat. No. Product Name / Synonyms Application Reactivity