2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

Related Products

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-171004
    KRN7000 analog 8 2300074-31-9 98%
    KRN7000 analog 8 (compound 8), KRN7000 (HY-102022) analogue, shows a good stimulatory effect on IL-2 production, induced less IFN-γ but more IL-4 production compared with KRN7000.
    KRN7000 analog 8
  • HY-171038
    STAT3-IN-39 3037596-35-0 98%
    STAT3-IN-39 (compound 10K) is an orally active STAT3 inhibitor that exhibits excellent inhibitory activity against STAT3 phosphorylation, with an IC50 of 0.47 μM in NIH-3T3 cells. STAT3-IN-39 inhibits the TGF-β1-induced fibrotic response and blocks the epithelial-mesenchymal transition in A549. STAT3-IN-39 can be utilized in research related to idiopathic pulmonary fibrosis.
    STAT3-IN-39
  • HY-171199
    In vivo Igkc Mouse Pre-designed siRNA-1 98%
    In vivo Igkc Mouse Pre-designed siRNA-1 is a siRNA product designed for the Igkc (Mouse) gene and can be used for in vivo experiments in mice.
    In vivo Igkc Mouse Pre-designed siRNA-1
  • HY-171200
    In vivo Igkc Mouse Pre-designed siRNA-2 98%
    In vivo Igkc Mouse Pre-designed siRNA-2 is a siRNA product designed for the Igkc (Mouse) gene and can be used for in vivo experiments in mice.
    In vivo Igkc Mouse Pre-designed siRNA-2
  • HY-171201
    In vivo Igkc Mouse Pre-designed siRNA-3 98%
    In vivo Igkc Mouse Pre-designed siRNA-3 is a siRNA product designed for the Igkc (Mouse) gene and can be used for in vivo experiments in mice.
    In vivo Igkc Mouse Pre-designed siRNA-3
  • HY-171208
    In vivo Stat1 Mouse Pre-designed siRNA-1 98%
    In vivo Stat1 Mouse Pre-designed siRNA-1 is a siRNA product designed for the Stat1 (Mouse) gene and can be used for in vivo experiments in mice.
    In vivo Stat1 Mouse Pre-designed siRNA-1
  • HY-171209
    In vivo Stat1 Mouse Pre-designed siRNA-2 98%
    In vivo Stat1 Mouse Pre-designed siRNA-2 is a siRNA product designed for the Stat1 (Mouse) gene and can be used for in vivo experiments in mice.
    In vivo Stat1 Mouse Pre-designed siRNA-2
  • HY-171210
    In vivo Stat1 Mouse Pre-designed siRNA-3 98%
    In vivo Stat1 Mouse Pre-designed siRNA-3 is a siRNA product designed for the Stat1 (Mouse) gene and can be used for in vivo experiments in mice.
    In vivo Stat1 Mouse Pre-designed siRNA-3
  • HY-171254
    p38-α MAPK-IN-9 868272-50-8 98%
    p38-α MAPK-IN-9 (Compound 25a) is a p38-α MAPK inhibitor (Ki: 0.057 nM). p38-α MAPK-IN-9 inhibits LPS (HY-D1056) induced TNFα production in hPBMCs (IC50: 18 nM).
    p38-α MAPK-IN-9
  • HY-171275
    p38 MAP Kinase-IN-1 815595-27-8 98%
    p38 MAP Kinase-IN-1 (Compound 4) is the inhibitor for p38, and can be used for inflammation and auto-immune responses related research.
    p38 MAP Kinase-IN-1
  • HY-171276
    Anti-neuroinflammation agent 3 928316-71-6 98%
    Anti-neuroinflammation agent 3 (Compound A.10.3) exhibits inhibitory activity against a variety of Ser/Thr kinase or receptor or non-receptor tyrosine kinase.
    Anti-neuroinflammation agent 3
  • HY-171291
    Protein kinase inhibitor 14 928319-09-9 98%
    Protein kinase inhibitor 14 (Compound 13) exhibits inhibitory effects against a variety of serine/threonine kinase and receptor/non-receptor tyrosine kinase.
    Protein kinase inhibitor 14
  • HY-171293
    Protein kinase inhibitor 15 928317-20-8 98%
    Protein kinase inhibitor 15 (Compound A.35.3) exhibits inhibitory activity against a variety of Ser/Thr kinase or receptor or non-receptor tyrosine kinase.
    Protein kinase inhibitor 15
  • HY-171294
    Protein kinase inhibitor 16 928316-79-4 98%
    Protein kinase inhibitor 16 exhibits inhibitory activity against a variety of Ser/Thr kinase or receptor or non-receptor tyrosine kinase.
    Protein kinase inhibitor 16
  • HY-171295
    p38 Kinase inhibitor 7 815595-14-3 98%
    p38 Kinase inhibitor 7 (Comp:XXXIX) is the inhibitor for p38α with an IC50 of 5.25 nM. p38 Kinase inhibitor 7 inhibits TNFα production in cell THP-1 with an IC50 of 5.88 nM.
    p38 Kinase inhibitor 7
  • HY-171296
    p38 Kinase inhibitor 8 815595-25-6 98%
    p38 Kinase inhibitor 8 (Compound CCLXXVIII) is the orally active inhibitor for p38β and JNK2α2 with IC50s of 6.3 nM and 53.6 nM. p38 Kinase inhibitor 8 exhibits anti-inflammatory effect in rats collagen-induced arthritis models.
    p38 Kinase inhibitor 8
  • HY-171448
    SU-740 134336-72-4 98%
    SU-740 is a chalcone derivative with anti-ulcer activity.
    SU-740
  • HY-171454
    DA-1241 1914136-10-9 98%
    DA-1241 is a GPR119 agonist. DA-1241 reduces macrophage differentiation through downregulation of NFκB signaling by activating GPR119. DA-1241, alone and in combination with a DPP4 inhibitor, reduces liver inflammation and restores inflammation-related liver gene expression. DA-1241 can be used for the research of metabolic dysfunction-associated steatohepatitis (MASH).
    DA-1241
  • HY-171460
    Win 45164 83880-39-1 98%
    Win 45164 is an orally active glucocorticoid receptor (Glucocorticoid Receptor) ligand with the activity of inhibiting the pituitary - adrenal axis. It can promote liver glycogen deposition and thymus involution in adrenalectomized male rats. Meanwhile, Win 45164 has anti - inflammatory effects. It can be used in the research of inflammatory and neurological diseases.
    Win 45164
  • HY-171462
    SMW139 2133010-38-3 98%
    SMW139 is a selective allosteric antagonist of P2X7 receptor, with a Ki value of 32 nM for human P2X7R. The half-life of SMW139 in rat liver microsomes is 47 minutes. SMW139 can be used for inflammation, Alzheimer’s disease, multiple sclerosis study.
    SMW139
Cat. No. Product Name / Synonyms Application Reactivity