1. Inflammation/Immunology

Inflammation/Immunology

The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-131103R
    Phenylethanolamine A (Standard) 1346746-81-3
    Phenylethanolamine A (Standard) is the analytical standard of Phenylethanolamine A. This product is intended for research and analytical applications. Phenylethanolamine A acts as a β-adrenergic agonist. Phenylethanolamine A is a byproduct during the Ractopamine synthesis process.
    Phenylethanolamine A (Standard)
  • HY-131103S
    Phenylethanolamine A-d3 2507994-61-6
    Phenylethanolamine A-d3 is a deuterium labeled Phenylethanolamine A. Phenylethanolamine A acts as a β-adrenergic agonist. Phenylethanolamine A is a byproduct during the Ractopamine synthesis process.
    Phenylethanolamine A-d3
  • HY-131515R
    Tri-Salicylic acid (Standard) 85531-17-5
    Tri-Salicylic acid (Standard) is the analytical standard of Tri-Salicylic acid (HY-131515). This product is intended for research and analytical applications. Tri-Salicylic acid (Compound III) is a compound with similar properties to salicylic acid. Tri-Salicylic acid can be used in the research of inflammation, obesity, diabetes, and cardiovascular disease.
    Tri-Salicylic acid (Standard)
  • HY-131579R
    Deschloro Cetirizine dihydrochloride (Standard) 83881-54-3
    Pyrocatechuic acid (Standard) is the analytical standard of Pyrocatechuic acid. This product is intended for research and analytical applications. Pyrocatechuic acid is a normal human benzoic acid metabolite found in plasma, and has increased levels after aspirin ingestion.
    Deschloro Cetirizine dihydrochloride (Standard)
  • HY-131688R
    2-Chlorohexadecanoic acid (Standard) 19117-92-1
    Neomycin (sulfate) (Standard) is the analytical standard of Neomycin (sulfate). This product is intended for research and analytical applications. Neomycin sulfate, an aminoglycoside antibiotic, exerts antibacterial activity through irreversible binding of the nuclear 30S ribosomal subunit, thereby blocking bacterial protein synthesis. Neomycin sulfate is a known phospholipase C (PLC) inhibitor. Neomycin sulfate potently inhibits both nuclear translocation of angiogenin and angiogenin-induced cell proliferation and angiogenesis.
    2-Chlorohexadecanoic acid (Standard)
  • HY-131910A
    (R)-IHMT-PI3Kδ-372 2429889-62-1 99.75%
    (R)-IHMT-PI3Kδ-372 (R-18) is a potent and selective PI3Kδ inhibitor with an IC50 of 19 nM. (R)-IHMT-PI3Kδ-372 (R-18) can be used in chronic obstructive pulmonary disease (COPD) research.
    (R)-IHMT-PI3Kδ-372
  • HY-131914B
    EST64454 maleate 2088272-67-5 98%
    EST64454 maleate is a highly soluble σ1 receptor antagonist, demonstrating potent antinociceptive properties for pain treatment. EST64454 maleate exhibits excellent metabolic stability across various species and possesses an adequate pharmacokinetic profile in rodents. EST64454 maleate has been identified as a promising clinical candidate due to its favorable aqueous solubility and high permeability in Caco-2 cells.
    EST64454 maleate
  • HY-132269S
    Isoflupredone-d5 98%
    Isoflupredone-d5 is deuterium-labeled Isoflupredone (HY-132269).
    Isoflupredone-d5
  • HY-13315BR
    Montelukast dicyclohexylamine (Standard) 577953-88-9
    Montelukast (dicyclohexylamine) (Standard) is the analytical standard of Montelukast (dicyclohexylamine). This product is intended for research and analytical applications. Montelukast (MK0476) dicyclohexylamine is a potent, selective and orally active antagonist of cysteinyl leukotriene receptor 1 (CysLT1). Montelukast dicyclohexylamine can be used for the reseach of asthma and liver injury. Montelukast dicyclohexylamine also has an antioxidant effect in intestinal ischemia-reperfusion injury, and could reduce cardiac damage. Montelukast dicyclohexylamine decreases eosinophil infiltration into the asthmatic airways. Montelukast dicyclohexylamine can also be used for COVID-19 research.
    Montelukast dicyclohexylamine (Standard)
  • HY-133178R
    Urolithin D (Standard) 131086-98-1
    Urolithin D (Standard) (3,4,8,9-Tetrahydroxy urolithin (Standard)) is the analytical standard of Urolithin D (HY-133178). This product is intended for research and analytical applications. Urolithin D (3,4,8,9-Tetrahydroxy urolithin) is a colonic metabolite of Ellagitannins and a competitive, reversible, and selective antagonist of the EphA receptor. Urolithin D inhibits EphA2-ephrin-A1 binding with an IC50 of 0.9 μM. Urolithin D is also a potent antioxidant that scavenges free radicals and repairs oxidized DNA damage. Additionally, Urolithin D suppresses triglyceride accumulation and promotes fatty acid oxidation by activating the AMPK signaling pathway. Urolithin D can be used for research on tumors, metabolic, and inflammatory diseases.
    Urolithin D (Standard)
  • HY-133724R
    Vardenafil N-oxide (Standard) 448184-48-3
    Vardenafil N-oxide (Standard) is the analytical standard of Vardenafil N-oxide. This product is intended for research and analytical applications. Vardenafil N-oxide is a N-Oxide impurity of Vardenafil (HY-B0442).
    Vardenafil N-oxide (Standard)
  • HY-133968R
    24-Methylenecholesterol (Standard) 474-63-5
    24-Methylenecholesterol (Ostreasterol) (Standard) is the analytical standard of 24-Methylenecholesterol (HY-133968). This product is intended for research and analytical applications. 24-Methylenecholesterol (Ostreasterol) is a regulator targeting acyl-CoA cholesterol acyltransferase (ACAT) with anti-aging and neuroprotective effects. 24-Methylenecholesterol mimics the effects of nerve growth factor (NGF), can extend yeast lifespan through an anti-oxidative stress mechanism, and exhibits neuroprotective activity in PC12 cells. 24-Methylenecholesterol can reduce intracellular reactive oxygen species (ROS) and malondialdehyde (MDA) levels, activate anti-oxidative stress pathways (such as UTH1, SOD-related genes), and promote synaptic growth.
    24-Methylenecholesterol (Standard)
  • HY-134242A
    6-T-5'-GMP 15867-02-4 98%
    6-T-5'-GMP (6-Thioguanosine monophosphate) is an analogue of guanosine-5'-O-monophosphate (5'-GMP) and a metabolite of an immunosuppressive drug, Azathioprine (HY-B0256).
    6-T-5'-GMP
  • HY-134440A
    α,β-Methylene-ATP 7292-42-4 98%
    α,β-Methylene-ATP is an agonist of P2X1 and P2X3 receptors and can cross the blood-brain barrier. α,β-Methylene-ATP can trigger a reflex pressor response by activating P2X receptors in peripheral muscles and the central locus coeruleus (LC); this effect can be blocked by the P2X antagonist PPADS (HY-108960). α,β-Methylene-ATP also activates noradrenergic neurons in the central locus coeruleus, mediating antinociceptive effects; this effect can be attenuated by the locus coeruleus damaging agent DSP-4 (HY-103210/HY-121602). α,β-Methylene-ATP can be used to study the pathological mechanisms of neuropathic pain, cardiovascular reflex regulation, and antinociceptive effects of the central nervous system.
    α,β-Methylene-ATP
  • HY-134520R
    21-Deacetoxy deflazacort (Standard) 13649-88-2
    21-Deacetoxy deflazacort (Standard) is the analytical standard of 21-Deacetoxy deflazacort. This product is intended for research and analytical applications. 21-Deacetoxy deflazacort is a dehydrogenated derivative of Deflazacort (HY-13609), a glucocorticoid, an inactive precursor that is rapidly converted to the active metabolite 21-Desacetyldeflazacort. Deflazacort acts as an anti-inflammatory and immunosuppressant.
    21-Deacetoxy deflazacort (Standard)
  • HY-134577S
    Clorprenaline-d6 1648796-40-0 98.0%
    Clorprenaline-d6 is the deuterium labeled Clorprenaline.
    Clorprenaline-d6
  • HY-13511AS
    Rupatadine-d4 fumarate 1795153-63-7 98%
    Rupatadine-d4 fumarate is a deuterium labeled Rupatadine fumarate. Rupatadine Fumarate (UR-12592 Fumarate) is a potent dual PAF/H1 antagonist with Ki values of 0.55/0.1 μM (rabbit platelet membranes/guinea pig cerebellum membranes).
    Rupatadine-d4 fumarate
  • HY-135325R
    4-Hydroxyacetophenone oxime (Standard) 34523-34-7
    Pyrrole-2-carboxaldehyde (Standard) is the analytical standard of Pyrrole-2-carboxaldehyde. This product is intended for research and analytical applications. Pyrrole-2-carboxaldehyde has vibrational and electronic characteristics used to establish the existence of dimeric form in solid phase and monomeric form in solution phase.
    4-Hydroxyacetophenone oxime (Standard)
  • HY-135326R
    4-Propionamidophenol (Standard) 1693-37-4
    4-Propionamidophenol (Standard) is the analytical standard of 4-Propionamidophenol. This product is intended for research and analytical applications. 4-Propionamidophenol is an important intermediate of alkanolamine derivatives with β-adrenergic blocking activity. 4-Propionamidophenol can be used in the study of diseases such as heart disease and hypertension.
    4-Propionamidophenol (Standard)
  • HY-135399S
    Tauro-obeticholic acid-d5 sodium 98%
    Tauro-obeticholic acid-d5 sodium is deuterium labeled Tauro-obeticholic acid sodium (HY-135399A). Tauro-obeticholic acid is an active metabolite of Obeticholic acid. Obeticholic acid is an orally bioavailable farnesoid-X receptor (FXR) agonist.
    Tauro-obeticholic acid-d5 sodium
Cat. No. Product Name / Synonyms Application Reactivity