1. Inflammation/Immunology

Inflammation/Immunology

The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-138985
    CAY10568 22913-17-3 98%
    CAY10568 is a compound based on QX-314 (HY-101350). CAY10568 is physically smaller and less hydrophobic than the QX-314. CAY10568 can be used in studies of inflammation and pain perception.
    CAY10568
  • HY-139095
    Cipamfylline 132210-43-6 98%
    Cipamfylline is a PDE4 inhibitor that can cause PDE4A4 to accumulate in specific areas of the cell through interaction with the ubiquitin scaffolding protein p62. Cipamfylline can be used in the research of atopic dermatitis.
    Cipamfylline
  • HY-139129
    N-(3-Pyridyl)indomethacinamide 261766-29-4 98%
    N-(3-Pyridyl)indomethacinamide is a derivative of Indomethacin (HY-14397). N-(3-Pyridyl)indomethacinamide is a COX2 inhibitor.
    N-(3-Pyridyl)indomethacinamide
  • HY-139171
    F092 2250261-59-5 99.79%
    F092 is an inhibitor of hematopoietic prostaglandin D synthase (H-PGDS) with a KD value of 0.14 nM. F092 can be used in the study of allergic and inflammatory responses.
    F092
  • HY-139223
    pEBOV-IN-1 1252187-41-9 98%
    pEBOV-IN-1 (Comp 2) is a pEBOV inhibitor, with an EC50 value of 0.38 μM. pEBOV: pseudotyped Ebola virus.
    pEBOV-IN-1
  • HY-139232
    17(R)-Resolvin D3 1427475-53-3 98%
    17(R)-Resolvin D3 is a metabolite of docosahexaenoic acid (DHA). 17(R)-Resolvin D3 has anti-inflammatory activity.
    17(R)-Resolvin D3
  • HY-139410
    Sodium caseinates 9005-46-3 98%
    Sodium caseinates, the salt of casein, are the main milk protein. Sodium caseinate are able to induce proliferation and activation of granulocytes as well as increase the serum concentration of two key cytokines, GM-CSF and G-CSF. Sodium caseinate induces mouse granulopoiesis.
    Sodium caseinates
  • HY-139433
    6-Hydroxy etodolac 101901-06-8 98%
    6-Hydroxy etodolac (compound 2) is a metabolite of Etodolac (HY-76251). Etodolac is a non-steroidal anti-inflammatory compound and is a COX inhibitor.
    6-Hydroxy etodolac
  • HY-141434
    5-OxoETE methyl ester 74785-00-5 98%
    5-OxoETE methyl ester is the agonist for oxoeicosanoid receptor 1 (OXER1). 5-OxoETE methyl ester binds to OXER1, and activates downstream signaling pathways β-arrestin recruitment with an EC50 of 1.54 µM.
    5-OxoETE methyl ester
  • HY-14144R
    Aclidinium Bromide (Standard) 320345-99-1
    Aclidinium (Bromide) (Standard) is the analytical standard of Aclidinium (Bromide). This product is intended for research and analytical applications. Aclidinium Bromide (LAS 34273; LAS-W 330) is a long-acting, inhaled muscarinic antagonist. Aclidinium Bromide has the potential for chronic obstructive pulmonary disease (COPD) research.
    Aclidinium Bromide (Standard)
  • HY-141569
    Ganglioside GD1a 12707-58-3 98%
    Ganglioside GD1a modulates toxic and inflammatory effects of E. coli lipopolysaccharide by preventing TLR4 translocation into lipid rafts. Ganglioside GD1a significantly reduces the effect of LPS on the decrease of cell survival and on stimulation of reactive oxygen species production.
    Ganglioside GD1a
  • HY-141639
    3-Hydroxyheptadecanoic acid 40165-89-7 98%
    3-Hydroxyheptadecanoic acid is a type of 3-hydroxy acid that can be used as a chemical marker for endotoxins.
    3-Hydroxyheptadecanoic acid
  • HY-142101
    3,4-Didehydroglabridin 214283-58-6 98%
    3,4-Didehydroglabridin is a natural product that can be found in licorice. 3,4-Didehydroglabridin exhibits protective activities against carbon tetrachloride-induced HepG2 cells injury. 3,4-Didehydroglabridin has the potential for the research of liver injury.
    3,4-Didehydroglabridin
  • HY-14270R
    Lodoxamide (Standard) 53882-12-5
    Lodoxamide (Standard) is the analytical standard of Lodoxamide. This product is intended for research and analytical applications. Lodoxamide (U-42585E free acid) is an antiallergic compound acting as a mast-cell stabilizer for the treatment of asthma and allergic conjunctivitis.
    Lodoxamide (Standard)
  • HY-14282R
    Lanoconazole (Standard) 101530-10-3
    Lanoconazole (Standard) is the analytical standard of Lanoconazole. This product is intended for research and analytical applications. Lanoconazole is a potent and orally active imidazole antifungal agent, shows a broad spectrum of activity against fungi in vitro and in vivo. Lanoconazole interferes with ergosterol biosynthesis by inhibiting sterol 14-alpha demethylase and blocking fungal membrane ergosterol biosynthesis. Lanoconazole can be used for the investigation of dermatophytosis and onychomycosis.
    Lanoconazole (Standard)
  • HY-14299C
    Indacaterol xinafoate 1000160-97-3 98%
    Indacaterol xinafoate is an orally active long-acting β2-adrenergic agonist (LABA) with bronchodilatory effect. Indacaterol inhibits NF-κB activity in a β-arrestin2-dependent manner, preventing further lung damage and improving lung function in COPD (chronic obstructive pulmonary disorder). Indacaterol xinafoate can be utilized in asthma research .
    Indacaterol xinafoate
  • HY-14397R
    Indomethacin (Standard) 53-86-1
    Indomethacin (Standard) is the analytical standard of Indomethacin. This product is intended for research and analytical applications. Indomethacin (Indometacin) is a potent, orally active COX1/2 inhibitor with IC50 values of 18 nM and 26 nM for COX-1 and COX-2, respectively. Indomethacin has anticancer activity and anti-infective activity. Indomethacin can be used for cancer, inflammation and viral infection research.
    Indomethacin (Standard)
  • HY-14447R
    Bilastine (Standard) 202189-78-4
    Bilastine (Standard) is the analytical standard of Bilastine. This product is intended for research and analytical applications. Bilastine is a histamine H1 receptor antagonist that can be used to treat allergic rhinoconjunctivitis and urticaria.
    Bilastine (Standard)
  • HY-14447S
    Bilastine-d6 1215358-58-9
    Bilastine-d6 is the deuterium labeled Bilastine. Bilastine is a selective histamine H1 receptor antagonist used for treatment of allergic rhinoconjunctivitis and urticaria.
    Bilastine-d6
  • HY-14518R
    Aminopterin (Standard) 54-62-6
    Aminopterin (Standard) is the analytical standard of Aminopterin. This product is intended for research and analytical applications. Aminopterin (4-Aminofolic acid), the 4-amino derivative of folic acid, is a folic acid antagonist. Aminopterin catalyses the reduction of folic acid to tetrahydrofolic acid, and competitively inhibits dihydrofolate reductase (DHFR) with a Ki of 3.7 pM. Aminopterin has anticancer and immunosuppressive activity. Aminopterin is used in treatment of pediatric leukemia.
    Aminopterin (Standard)
Cat. No. Product Name / Synonyms Application Reactivity