1. Inflammation/Immunology

Inflammation/Immunology

The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-128447R
    Allyl methyl sulfide (Standard) 10152-76-8
    Allyl methyl sulfide (Standard) is the analytical standard of Allyl methyl sulfide (HY-128447). This product is intended for research and analytical applications. Allyl methyl sulfide is an orally active organic sulfide. Allyl methyl sulfide is one of the main active ingredients in garlic volatile metabolites. Allyl methyl sulfide can be extracted from garlic. Allyl methyl sulfide enhances SOD activity, inhibits NF-κB signaling pathway, and upregulates pancreatic GLUT2 expression. Allyl methyl sulfide has significant antioxidant, anti-inflammatory and hypoglycemic activities. Allyl methyl sulfide can be used in the research of diabetes and its complications.
    Allyl methyl sulfide (Standard)
  • HY-128525R
    Enterobactin (Standard) 28384-96-5
    Enterobactin (Standard) is the analytical standard of Enterobactin. This product is intended for research and analytical applications. Enterobactin is a siderophore produced by Gram-negative bacteria and has an extremely high affinity for iron. During the process of Salmonella typhimurium infecting macrophages, Enterobactin can not only help bacteria uptake iron but also reduce the antibacterial activity of macrophages. In addition, Enterobactin is also involved in the oxidative stress response of Escherichia coli. Enterobactin can be hydrolyzed by Fes in the cell and exert antioxidant effects by scavenging free radicals.
    Enterobactin (Standard)
  • HY-128741R
    D-Allose (Standard) 2595-97-3
    D-Allose (Standard) is the analytical standard of D-Allose (HY-128741). This product is intended for research and analytical applications. D-Allose exhibits antitumor activity against various cancer cells. D-Allose scavenges reactive oxygen species (ROS) and reduces oxidative stress damage. D-Allose exhibits anti-inflammatory and neuroprotective through inhibition of TLR4/PI3K/AKT signaling pathway. D-Allose exhibits antihypertensive, cryoprotective, and anti-osteoporotic activities.
    D-Allose (Standard)
  • HY-128754R
    Monoolein (Standard) 111-03-5
    Monoolein is a biocompatible lipid molecule that can be used as a carrier for bone repair. Monoolein exhibits anti-inflammatory activity by inhibiting the immune response induced by LPS (HY-D1056). It exerts its anti-inflammatory effects by reducing the production of immune response factors such as IL-12 p40, IL-6, and TNF-α, and inhibiting the generation of NO. Monoolein can be used in drug delivery and research in the field of inflammatory diseases .
    Monoolein (Standard)
  • HY-128853R
    Taurodeoxycholate sodium salt (Standard) 1180-95-6
    Taurodeoxycholate sodium salt (Standard) is a bile salt (Standard)-related anionic detergent. Taurodeoxycholate sodium salt (Standard) is formed in the liver by conjugation of deoxycholate with Taurine (HY-B0351). Taurodeoxycholate sodium salt (Standard) is used for isolation of membrane proteins including inner mitochondrial membrane proteins. Taurodeoxycholate (TDCA) exhibits anti-inflammatory and neuroprotective effects.
    Taurodeoxycholate sodium salt (Standard)
  • HY-129029R
    Bisoprolol (Standard) 66722-44-9
    Bisoprolol (Standard) is the analytical standard of Bisoprolol. This product is intended for research and analytical applications. Bisoprolol is a potent, selective and orally active β1-adrenergic receptor blocker with little activity on β2-receptor. Bisoprolol has the potential for hypertension, coronary artery disease and stable ventricular dysfunction research.
    Bisoprolol (Standard)
  • HY-129047E
    Trypsin, porcine pancreas (Cell culture grade) 9002-07-7
    Trypsin, porcine pancreas (Cell culture grade) is a serine protease enzyme that hydrolyzes proteins at the carboxyl side of the Lysine or Arginine. Trypsin, porcine pancreas (Cell culture grade) has an excellent protein digestibility for α-lactalbumin and β-casein. Trypsin, porcine pancreas (Cell culture grade) activates kallikrein and regulates the blood pressure. Trypsin, Human Pancreas is an activator for PAR, thereby regulating cellular inflammatory and immune responses.
    Trypsin, porcine pancreas (Cell culture grade)
  • HY-129138R
    Cyanidin 3,5-diglucoside chloride (Standard) 2611-67-8
    Cyanidin 3,5-diglucoside (chloride) (Standard) is the analytical standard of Cyanidin 3,5-diglucoside (chloride) (HY-129138). This product is intended for research and analytical applications. Cyanidin 3,5-diglucoside chloride is an anthocyanin. Cyanidin 3,5-diglucoside chloride inhibits inflammatory cytokines (IL-1α, IL-1β, and IL-6) expression and NO production. Cyanidin 3,5-diglucoside chloride inhibits the phosphorylation of STAT3, IκB, ERK, p38, and AKT. Cyanidin 3,5-diglucoside chloride inhibits high pressure-induced decrease in GLAST. Cyanidin 3,5-diglucoside chloride exerts anti-inflammatory and skin barrier modulating effects. Cyanidin 3,5-diglucoside chloride can be used in retinal research.
    Cyanidin 3,5-diglucoside chloride (Standard)
  • HY-129143R
    Delphinidin-3-sambubioside chloride (Standard) 53158-73-9
    Delphinidin-3-sambubioside (chloride) (Standard) is the analytical standard of Delphinidin-3-sambubioside (chloride). This product is intended for research and analytical applications. Delphinidin-3-sambubioside (Dp3‐Sam) chloride is an anthocyanin that has orally active anti-inflammatory activity. Delphinidin-3-sambubioside chloride inhibits LPS-induced inflammatory factors release. Delphinidin-3-sambubioside chloride also alleviates hepatic lipid accumulation in HFD rats. Delphinidin-3-sambubioside chloride can be isolated from Hibiscus sabdariffa L..
    Delphinidin-3-sambubioside chloride (Standard)
  • HY-129240S
    13-cis Acitretin-d3 1185241-03-5 98%
    13-cis Acitretin-d3 is a deuterium labeled 13-cis Acitretin. 13-cis Acitretin is the metabolite of Acitretin after chronic administration. Acitretin(Ro 10-1670) is a second-generation, systemic retinoid that has been used in the treatment of psoriasis.
    13-cis Acitretin-d3
  • HY-129566R
    Withanolide B (Standard) 56973-41-2
    Withanolide B (Standard) is the analytical standard of Withanolide B. This product is intended for research and analytical applications. Withanolide B is an active component of W. somnifera Dunal. Withanolide B promotes osteogenic differentiation of hBMSCs via ERK1/2 and Wnt/β-catenin signaling pathways. Withanolide B exhibits neuroprotective, anti-arthritic, anti-aging and anti-cancer effects.
    Withanolide B (Standard)
  • HY-129764A
    (17E)-Prostaglandin F3α 211100-24-2 98%
    (17E)-Prostaglandin F3α (17-trans-PGF3α) is a double bond isomer of Prostaglandin F3α (HY-129764) and a potential metabolite of trans dietary fatty acids. (17E)-Prostaglandin F3α has anti-inflammatory activity.
    (17E)-Prostaglandin F3α
  • HY-129853A
    Doxpicomine 62904-71-6 98%
    Doxpicomine is an analgesic with potent activity, effective in treating severe postoperative pain.
    Doxpicomine
  • HY-129953B
    15(R)-Prostaglandin F2α 37658-84-7 98%
    15(R)-Prostaglandin F2α is the isomer of 9α,11β-Prostaglandin F2α (HY-129953). 9α,11β-Prostaglandin F2α is an endogenous metabolite present in Urine that can be used for the research of Asthma.
    15(R)-Prostaglandin F2α
  • HY-129953S
    9α,11β-Prostaglandin F2α-d4 98%
    9α,11β-Prostaglandin F2α-d4 is a deuterated labeled 9α,11β-Prostaglandin F2α. 9α,11β-Prostaglandin F2α is an endogenous metabolite present in Urine that can be used for the research of Asthma.
    9α,11β-Prostaglandin F2α-d4
  • HY-130138A
    (5S,6R)-DiHETE 82948-88-7 98%
    (5S,6R)-DiHETE is an enantiomer of (5,6)-DiHETEs. (5S,6R)-DiHETE can be recognized by leukotriene receptors (LTD4 receptors). (5S,6R)-DiHETE can induce guinea pig isolated ileum contraction with an EC50 of 1.3 μM, and this effect can be inhibited by LTD4 receptor antagonists.
    (5S,6R)-DiHETE
  • HY-130138B
    (5S,6R)-DiHETEs 129263-59-8 98%
    (5S,6R)-DiHETEs is the isomer of (5S,6R)-DiHETE (HY-130138A). (5S,6R)-DiHETE can be recognized by leukotriene receptors (LTD4 receptors). (5S,6R)-DiHETE can induce guinea pig isolated ileum contraction with an EC50 of 1.3 μM, and this effect can be inhibited by LTD4 receptor antagonists.
    (5S,6R)-DiHETEs
  • HY-130246A
    NF-56-EJ40 hydrochloride 2728500-80-7 98%
    NF-56-EJ40 hydrochloride is a potent, high-affinity, and highly selective human SUCNR1 (GPR91) antagonist with an IC50 of 25 nM and a Ki of 33 nM, and shows almost no activity towards rat SUCNR1. NF-56-EJ40 hydrochloride has high affinity for humanized rat SUCNR1 with a Ki value of 17.4 nM.
    NF-56-EJ40 hydrochloride
  • HY-130320A
    Monophosphoryl lipid A free acid 960324-04-3 98%
    Monophosphoryl lipid A (free acid) is a toll-like receptor 4 agonist. Monophosphoryl lipid A (free acid) is derived from the cell wall of nonpathogenic Salmonella. Monophosphoryl lipid A (free acid) can be used for the research of immunization and vaccine.
    Monophosphoryl lipid A free acid
  • HY-130320B
    Monophosphoryl lipid A Triethylamine 98%
    Monophosphoryl lipid A (Triethylamine) is a toll-like receptor 4 agonist. Monophosphoryl lipid A (Triethylamine) is derived from the cell wall of nonpathogenic Salmonella. Monophosphoryl lipid A (Triethylamine) can be used for the research of immunization and vaccine.
    Monophosphoryl lipid A Triethylamine
Cat. No. Product Name / Synonyms Application Reactivity