2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

Related Products

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-12886R
    Docebenone (Standard) 80809-81-0
    Docebenone (Standard) is the analytical standard of Docebenone. This product is intended for research and analytical applications. Docebenone (AA 861) is a potent, selective and orally active 5-LO (5-lipoxygenase) inhibitor.
    Docebenone (Standard)
  • HY-12887R
    Piclamilast (Standard) 144035-83-6
    Piclamilast (Standard) is the analytical standard of Piclamilast. This product is intended for research and analytical applications. Piclamilast (RP 73401) is a phosphodiesterase 4 (PDE4) inhibitor, with IC50 values of 16 nM and 2 nM in pig aorta and eosinophil soluble, respectively.
    Piclamilast (Standard)
  • HY-129258
    Lycoctonine 26000-17-9 98%
    Lycoctonine is a diterpene alkaloid. Lycoctonine interacts the sodium channel, affects the heart and central nervous system, exhibits analgesic, anti-inflammatory, anti-epileptic and cardiovascular activities.
    Lycoctonine
  • HY-129306
    Gilvocarcin M 77879-89-1 98%
    Gilvocarcin M is an antibiotic and can be isolated from S. gilvotanareus. Gilvocarcin M is active against S. aureus at a concentration of 32 µg/ml and inhibits growth of KB cells with the IC50 of 0.52 µg/ml. Gilvocarcin M intercalates into bacteriophage PM2 DNA.
    Gilvocarcin M
  • HY-129338
    CID 7309015 1164457-99-1 98%
    CID 7309015 is an inhibitor of retinoic acid-related orphan receptor gamma (ROR-γ). CID 7309015 can be used for research of inflammation, NF-κB signaling or inflammatory arthritis.
    CID 7309015
  • HY-129508
    Amthamine 142437-67-0 98%
    Amthamine is a histamine receptor (H1R-H4R) agonist. Amthamine can produce liver congestion and necrosis of liver cells. Amthamine can be used to study the induction effect of H1R-H4 agonist on hepatotoxicity .
    Amthamine
  • HY-129577
    Aplysin 6790-63-2 98%
    Aplysin is a brominated sesquiterpene with an isoprene backbone that exhibits hepatoprotective, immunomodulatory, and antitumor activities. Aplysin effectively prevents spontaneous pancreatic necrosis and inflammatory responses in NOD mice.
    Aplysin
  • HY-129584
    Lepidiline B 596093-97-9 98%
    Lepidiline B is a flavonolignan isolated from the roots of Brassicaceae Lepidium meyenii. Lepidiline B exhibits anti-inflammation activities in human cancer cell lines.
    Lepidiline B
  • HY-129624
    Bisindolylmaleimide VIII 125313-65-7 98%
    Bisindolylmaleimide VIII (Ro 31-7549) is a potent and selective protein kinase C (PKC) inhibitor with an IC50 of 158 nM for rat brain PKC. Bisindolylmaleimide VIII has IC50s of 53, 195, 163, 213, and 175 nM for PKC-α, PKC-βI, PKC-βII, PKC-γ, PKC-ε, respectively. Bisindolylmaleimide VIII facilitates Fas-mediated apoptosis and inhibits T cell-mediated autoimmune diseases.
    Bisindolylmaleimide VIII
  • HY-129728
    Lienomycin 12710-02-0 98%
    Lienomycin, a polyene antibiotic produced by Actinomyces distatochromogenes var. lienomycini, exhibits antifungal, antibacterial and antitumor activity.
    Lienomycin
  • HY-129755
    CK-17 86727-00-6 98%
    CK-17 is an orally active and potent anti-inflammatory agent. CK-17 shows potent inhibition of ocular inflammation induced by lens protein, endotoxin, and IL-1. The effects on IL-1-induced inflammation are about 2 fold more potent than Prednisolone (HY-17463).
    CK-17
  • HY-129759
    KSG-504 anhydrous 137005-17-5 98%
    KSG-504 (anhydrous) is a CCK receptor antagonist. KSG-504 (anhydrous) inhibits the development of Ethionine-induced acute pancreatitis in rats and facilitates the regeneration of acinar cells.
    KSG-504 anhydrous
  • HY-129761
    AR 17048 65792-35-0 98%
    AR 17048 is a potent antirheumatic agent.
    AR 17048
  • HY-129783
    Phenindamine tartrate 569-59-5 98%
    Phenindamine tartrate is a Histamine H1-receptor antagonist. Phenindamine tartrate is an antihistamine.
    Phenindamine tartrate
  • HY-129785
    CP-220629 162141-96-0 98%
    CP-220629 is a potent inhibitor of PDE4, with the IC50 of 0.44 μM. CP-220629 is efficacious in the guinea pig aerosolized antigen induced airway obstruction assay (ED50 2.0 mg/kg).
    CP-220629
  • HY-12980R
    Batefenterol (Standard) 743461-65-6
    Batefenterol (Standard) is the analytical standard of Batefenterol. This product is intended for research and analytical applications. Batefenterol (GSK961081;TD-5959) is a novel muscarinic receptor antagonist and β2-adrenoceptor agonist; displays high affinity for hM2, hM3 muscarinic and hβ2-adrenoceptor with Ki values of 1.4, 1.3 and 3.7 nM, respectively.
    Batefenterol (Standard)
  • HY-13010R
    Laquinimod (Standard) 248281-84-7
    Laquinimod (Standard) is the analytical standard of Laquinimod. This product is intended for research and analytical applications. Laquinimod (ABR-215062), an orally available carboxamide derivative, is a potent immunomodulator which prevents neurodegeneration and inflammation in the central nervous system. Laquinimod reduces astrocytic NF-κB activation to protect from Cuprizone-induced demyelination. Laquinimod has the potential for relapsing remitting (RR) and chronic progressive (CP) forms of multiple sclerosis (MS; RRMS or CPMS) as well as neurodegenerative diseases research.
    Laquinimod (Standard)
  • HY-130285
    10(S),17(S)-DiHDHA 871826-47-0 98%
    10(S),17(S)-DiHDHA (also known as neuroprotectin D1 when produced in neuronal tissues) is a DHA-derived dihydroxy fatty acid that exhibits potent protective and anti-inflammatory activities.
    10(S),17(S)-DiHDHA
  • HY-130322
    Maresin Conjugates in Tissue Regeneration 2 1784701-62-7 98%
    Maresin Conjugates in Tissue Regeneration 2 is a specialized pro-resolving mediator (SPM). Maresin Conjugates in Tissue Regeneration 2 can be used in the study of anti-inflammatory.
    Maresin Conjugates in Tissue Regeneration 2
  • HY-13038R
    Fostamatinib Disodium (Standard) 1025687-58-4
    Fostamatinib Disodium (Standard) is the analytical standard of Fostamatinib Disodium. This product is intended for research and analytical applications. Fostamatinib Disodium (R788 Disodium) is the oral proagent of the active compound R406. R406 is an orally available and competitive Syk/FLT3 inhibitor with a Ki of 30 nM and an IC50 of 41 nM. R406 also inhibits Lyn (IC50=63 nM) and Lck (IC50=37 nM).
    Fostamatinib Disodium (Standard)
Cat. No. Product Name / Synonyms Application Reactivity