2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

Related Products

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-120486
    LY203647 122009-61-4 98%
    LY203647 is an orally active antagonist for leukotriene receptor LTD4 and LTE4. LY203647 can be used in research about asthma and other inflammation diseases.
    LY203647
  • HY-120533
    Syk-IN-11 1194954-83-0 98%
    Syk-IN-11 (BIIB-057) is a selective Syk inhibitor with an IC50 Of 13 nM. Syk-IN-11 can be used in the study of arthritis and chronic lymphocytic leukemia.
    Syk-IN-11
  • HY-120606
    A-78773 141579-67-1 98%
    A-78773 is a 5-lipoxygenase inhibitor. A-78773 can inhibit the formation of LTB4 in human whole blood and human neutrophils, with IC50 values of 85 nM and 20 nM, respectively. A-78773 can be used in the study of inflammation-related diseases.
    A-78773
  • HY-12066R
    GSK1292263 (Standard) 1032823-75-8
    GSK1292263 (Standard) is the analytical standard of GSK1292263. This product is intended for research and analytical applications. GSK-1292263 is an orally available GPR119 agonist with pEC50s of 6.9 and 6.7 for human and rat GPR119, respectively. GSK-1292263 can be used for the research of type 2 diabetes mellitus (T2DM).
    GSK1292263 (Standard)
  • HY-120755
    LY290324 146554-87-2 98%
    LY290324 is a potent and orally active leukotriene D4 (LTD4) antagonist. LY290324 reduces LTC4, LTD4 and LTE4 (HY-113465)-induced bronchospasm. LY290324 has the potential for the research of antigen-induced bronchospasm.
    LY290324
  • HY-12085R
    Apremilast (Standard) 608141-41-9
    Apremilast (Standard) is the analytical standard of Apremilast. This product is intended for research and analytical applications. Apremilast (CC-10004) is an orally available inhibitor of type-4 cyclic nucleotide phosphodiesterase (PDE-4) with an IC50 of 74 nM. Apremilast inhibits TNF-α release by lipopolysaccharide (LPS) with an IC50 of 104 nM.
    Apremilast (Standard)
  • HY-120865
    1,3-PBIT dihydrobromide 200716-66-1 98%
    1,3-PBIT is a potent inhibitor of iNOS with a Ki of 47 nM compared to Ki values for eNOS and nNOS are 9 and 0.25 μM, respectively, for the purified human enzymes. Its inhibition in whole cells is greatly diminished, presumably to poor membrane permeability.
    1,3-PBIT dihydrobromide
  • HY-12100R
    Umeclidinium bromide (Standard) 869113-09-7
    Umeclidinium (bromide) (Standard) is the analytical standard of Umeclidinium (bromide). This product is intended for research and analytical applications. Umeclidinium bromide is a novel mAChR antagonist. The affinity (Ki) of Umeclidinium bromide for the cloned human M1-M5 mAChRs ranges from 0.05 to 0.16 nM.
    Umeclidinium bromide (Standard)
  • HY-121039
    Avenin 6309-98-4 98%
    Avenin is a storage protein derived from oats, containing peptide sequences that can be specifically recognized by T cells and activate immune responses, potentially triggering celiac disease (CD). Avenin can be utilized in research related to autoimmune diseases.
    Avenin
  • HY-12136R
    Purpurogallin (Standard) 569-77-7
    Purpurogallin (Standard) is the analytical standard of Purpurogallin. This product is intended for research and analytical applications. Purpurogallin is a naturally phenol extracted from the plants of Quercus spp, has potent xanthine oxidase (XO) inhibitory activity with an IC50 of 0.2 μM. Purpurogallin has antioxidant and anti-inflammatory effects.
    Purpurogallin (Standard)
  • HY-121441
    Fispemifene 341524-89-8 98%
    Fispemifene, an orally active selective estrogen receptor modulator with anti-inflammatory and antiestrogenic action, attenuates glandular inflammation in an animal model of chronic nonbacterial prostatitis.
    Fispemifene
  • HY-121491
    ONO-6126 401519-28-6 98%
    ONO-6126 is a PDE4 inhibitor that can be used in research for asthma and chronic obstructive pulmonary disease.
    ONO-6126
  • HY-12159A
    MK-0668 mesylate 865111-04-2 98%
    MK-0668 mesylate is an amino acid-based, potent antagonist of unactivated VLA-4, with an IC50) of 0.13 nM in human whole blood. And MK-0668 mesylate exhibits IC50s of 0.19 nM in dogs, 0.21 nM in rhesus monkeys, and 0.4 nM in rats.
    MK-0668 mesylate
  • HY-121619
    Jacaric acid 28872-28-8 98%
    Jacaric acid is a conjugated linolenic acid, which inhibits viability in cells PC-3 (IC50 is 11.8 μM), LNCaP (IC50 is 2.2 μM) and DLD-1, induces apoptosis and necrosis. Jacaric acid exhibits anticaner activity against prostate cancer and adenocarcinoma. Jacaric acid exhibits immunomodulating activity in murine peritoneal macrophages as an immunopotentiator. Jacaric acid is orally active.
    Jacaric acid
  • HY-121889
    FQ 190838-76-7 98%
    FQ is a tyrosinase inhibitor that effectively inhibits the diphenolase activity of mushroom tyrosinase (IC50=120 μM). FQ can be used in the study of pigmentation.
    FQ
  • HY-121977
    IKs124 199335-15-4 98%
    IKs124 is KCNE2/KCNQ1 potassium channel blocker with the with an IC50 of 8 nM. IKs124 can be used for study of peptic ulcers.
    IKs124
  • HY-122063
    FR260330 442198-67-6 98%
    FR260330 is a selective, orally active inhibitor for inducible nitric oxide synthase (iNOS) through suppression of iNOS dimerization. FR260330 inhibits the NO accumulation in rat splenocytes and human DLD-110 cells, with IC50 of 27 and 10 nM. FR260330 ameliorates the Lipopolysaccharides (HY-D1056)-induced inflammatory diseases in rats model.
    FR260330
  • HY-122124
    CAY10583 862891-27-8 98%
    CAY10583 is a potent and selective full Leukotriene B4 receptor type 2 (BLT2) agonist. CAY10583 directly promotes keratinocyte migration in vitro and accelerates wound closure in vivo. CAY10583 is a promising pharmaceutical agent for diabetic wounds.
    CAY10583
  • HY-122153
    VSN-16 863713-78-4 98%
    VSN-16 is a cannabinoid receptor agonist with vasodilatory activity. VSN-16 can be used for the study of multiple sclerosis.
    VSN-16
  • HY-122158
    CRAC channel inhibitor-1 903591-53-7 98%
    CRAC channel inhibitor-1 (compound 55) is a CRAC channel inhibitor. CRAC channel inhibitor-1 can be used in immunology-related research.
    CRAC channel inhibitor-1
Cat. No. Product Name / Synonyms Application Reactivity