1. Inflammation/Immunology

Inflammation/Immunology

The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-105025
    Thymocartin 85466-18-8 98%
    Thymocartin (Thymopoietin II (32-35)) is the 32-35 fragment of the thymic factor (thymopoietin). Thymocartin has shown potential for immunodeficiency diseases research.
    Thymocartin
  • HY-105142
    M-5011 76604-64-3 98%
    M-5011 is a potent and orally active anti-inflammatory agent. M-5011 shows potent antinociceptive effects and inhibits kaolin (HY-W115786)-induced writhing. M-5011 decreases peritoneal 6-keto-PGF1 alpha levels with low ulcerogenic activities. M-5011 shows anti-inflammatory and anti-pyretic effects and analgesic effect.
    M-5011
  • HY-105176
    Ontazolast 147432-77-7 98%
    Ontazolast (BIRM 270) is a potent inhibitor of LTB4 biosynthesis. Ontazolast can be used in research on asthma.
    Ontazolast
  • HY-105191
    Azalanstat 143393-27-5 98%
    Azalanstat is an imidazole-dioxolane derivate that is a lanosterol 14-α demethylase inhibitor. Azalanstat is also a HO-1 (IC50 = 5.5 µM) and HO-2 (IC50 = 24.5 µM) inhibitor.
    Azalanstat
  • HY-105304
    COX-2-IN-36 189954-93-6 98%
    COX-2-IN-36 (compound 1) is a very potent and specific COX-2 inhibitor, with an IC50 of 0.4 μM.
    COX-2-IN-36
  • HY-105460
    TEI-6472 151379-49-6 98%
    TEI-6472, a naphthalene derivative, can suppress IgE responses both in vitro and in vivo. TEI-6472 causes significant inhibition of FceRI-mediated histamine release.
    TEI-6472
  • HY-105516
    E5090 131420-91-2 98%
    E5090 is an orally active inhibitor of IL-1 generation which is converted in vivo into the pharmacologically active deacetylated form (DA-E5090). E5090 can be utilized in immunology research.
    E5090
  • HY-10569R
    Ponesimod (Standard) 854107-55-4 98%
    Ponesimod (Standard) is the analytical standard of Ponesimod. This product is intended for research and analytical applications. Ponesimod (ACT-128800) is a potent, selective and orally active agonist of S1P1, with an IC50 of 6 nM in a radioligand binding assay. Ponesimod activates S1P1-mediated signal transduction with high potency (EC50=5.7 nM). Ponesimod can protect against lymphocyte-mediated tissue inflammation.
    Ponesimod (Standard)
  • HY-10582R
    Flurbiprofen (Standard) 5104-49-4
    Flurbiprofen (Standard) is the analytical standard of Flurbiprofen. This product is intended for research and analytical applications. Flurbiprofen (dl-Flurbiprofen) is a potent, orally active nonsteroidal anti-inflammatory agent (NSAIA/NSAID), with antipyretic and analgesic activities. Flurbiprofen is commonly used for the research of inflammatory diseases, including osteoarthritis and rheumatoid arthritis. Flurbiprofen is a non-selective cyclooxygenase (COX) inhibitor that can be used for the research of colorectal cancer.
    Flurbiprofen (Standard)
  • HY-106083
    Quazolast 86048-40-0 98%
    Quazolast (RHC 3988) is a orally active mast cell stabilizer. Quazolast also is a potent mediator release inhibitor. Quazolast reduces the gastric damage. Quazolast has the potential for the research of gastric ulcers.
    Quazolast
  • HY-106104
    Inocoterone acetate 83646-86-0 98%
    Inocoterone acetate (RU-38882) is a nonsteroidal antiandrogen. Inocoterone acetate binds to the androgen receptor and has antiandrogenic activity in animal models. Inocoterone acetate reduces inflammatory papules and pustules.
    Inocoterone acetate
  • HY-106333
    Irtemazole 129369-64-8 98%
    Irtemazole is an orally active antifungal agent. Irtemazole possesses uricosuric effect. Irtemazole is used in the research for blastomycosis, histoplasmosis, and aspergillosis.
    Irtemazole
  • HY-106350
    Cefpimizole 84880-03-5 98%
    Cefpimizole (U-63196E) is a broad-spectrum cephalosporin antibiotic. Cefpimizole inhibits many Ampicillin (HY-B0522)-resistant bacteria, and is active against gram-negative species. Cefpimizole augments phagocytosis of macrophages and neutrophils.
    Cefpimizole
  • HY-10635A
    (S)-ABT-102 808756-70-9 98%
    (S)-ABT-102 is a TRPV1 Antagonist, with an IC50 of 123 nM. (S)-ABT-102 has analgesic activity.
    (S)-ABT-102
  • HY-106448
    Midesteine 94149-41-4 98%
    Midesteine (MR 889) is a proteinase inhibitor that can inhibit porcine pancreatic elastase, human neutrophil elastase and bovine chymotrypsin. Midesteine has the potential for chronic obstructive pulmonary disease (COPD) and chronic bronchitis research.
    Midesteine
  • HY-106473
    Delmetacin 16401-80-2 98%
    Delmetacin is an anti-inflammatory agent.
    Delmetacin
  • HY-106514
    Prifelone 69425-13-4 98%
    Prifelone (R 830; R 830T; S 16820) is a di-tert-butylphenol with anti-inflammatory and antioxidant activity. Prifelone inhibits guinea pig lung oxygenase and bovine seminal vesicle cyclooxygenase.
    Prifelone
  • HY-106897
    BF389 127245-22-1 98%
    BF389 (Biofor 389) is an orally active anti-inflammatory and analesis agent. BF389 is also an inhibitor of cyclooxygenase and 5-lipoxygenase, with IC50s of 4 and 8 ug/mL for COX-1 and COX-2 respectively. BF389 can be used for arthritis research.
    BF389
  • HY-106996
    AWD 12-281 257892-33-4 98%
    AWD 12-281 is an orally active and highly selective phosphodiesterase 4 (PDE4) inhibitor (IC50 = 9.7 nM). AWD 12-281 is used in the study of allergic dermatitis, asthma, chronic obstructive pulmonary disease (COPD), and allergic rhinitis.
    AWD 12-281
  • HY-107004
    Amotosalen 161262-29-9 98%
    Amotosalen (S-59 (free base)) is a light-activated, DNA and RNA-crosslinking psoralen compound, which is used to neutralise pathogens.
    Amotosalen
Cat. No. Product Name / Synonyms Application Reactivity