2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

Related Products

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-100274
    Adenosine antagonist-1 431040-19-6 99.79%
    Adenosine antagonist-1 is an adenosine A3 receptor (AA3R) antagonist with anti-inflammatory activity.
    Adenosine antagonist-1
  • HY-100278
    AKP-001 897644-83-6 98%
    AKP-001 is an inhibitor of p38 mitogen-activated protein kinase (p38 MAPK). AKP-001 can inhibit the production of inflammatory cytokines and can be used for research in rheumatoid arthritis and inflammatory bowel disease.
    AKP-001
  • HY-100283
    CGS 15435 95853-92-2 98%
    CGS 15435, a potent thromboxane (TxA2) synthetase inhibitor with an IC50 of 1 nM, has a selectivity for Tx synthetase 100000-fold greater than that for cyclooxygenase, PGI2 synthetase and lipoxygenase enzymes.
    CGS 15435
  • HY-100284
    Thiazolidinone-Derivatives-1 136272-75-8 98%
    Thiazolidinone-Derivatives-1 is an antiulcer agent which inhibits the secretion of gastric acid.
    Thiazolidinone-Derivatives-1
  • HY-100316
    CP-96486 139401-45-9 98%
    CP-96486 is a potent and orally active leukotriene D4 (LTD4)/platelet activating factor (PAF) receptor antagonist with Kis of 20 and 24 nM, respectively.
    CP-96486
  • HY-10037R
    Quiflapon (Standard) 136668-42-3 98%
    Quiflapon (Standard) is the analytical standard of Quiflapon. This product is intended for research and analytical applications. Quiflapon (MK-591) is a selective and specific 5-lipoxygenase-activating protein (FLAP) inhibitor with an IC50?of 1.6 nM in a FLAP binding assay. Quiflapon is also a potent and orally active?Leukotriene biosynthesis (LT)?inhibitor, shows IC50?values of 3.1 and 6.1 nM in intact human and elicited rat PMNLs, respectively. Quiflapon induces cell apoptosis.
    Quiflapon (Standard)
  • HY-10046R
    Plerixafor (Standard) 110078-46-1
    Plerixafor (Standard) is the analytical standard of Plerixafor. This product is intended for research and analytical applications. Plerixafor (AMD 3100) is a selective CXCR4 antagonist with an IC50 of 44 nM. Plerixafor, an immunostimulant and a hematopoietic stem cell (HSC) mobilizer, is an allosteric agonist of CXCR7. Plerixafor inhibits HIV-1 and HIV-2 replication with an EC50 of 1-10 nM.
    Plerixafor (Standard)
  • HY-10053B
    Maropitant citrate 862543-54-2 98%
    Maropitant citrate is an orally active NK1 receptor antagonist. Maropitant citrate prevents vomiting and inhibits ulcerative dermatitis.
    Maropitant citrate
  • HY-100640
    Roflumilast Impurity E 1391052-76-8 98%
    Roflumilast Impurity E is the impurity of Roflumilast. Roflumilast(Daliresp) is a agent which acts as a selective and long-acting inhibitor of the enzyme PDE-4 with an IC50 value of 0.8 nM.
    Roflumilast Impurity E
  • HY-101581
    Bucloxic acid 32808-51-8 98%
    Bucloxic acid is an anti-inflammatory pyrrazole derivative. Bucloxic acid can be used for study of chronic glomerular nephropathies.
    Bucloxic acid
  • HY-101601
    Bamirastine 215529-47-8 98%
    Bamirastine inhibits ligand binding to recombinant human histamine H1 receptors (rhH1R) with an IC50 value of 17.3 nM.
    Bamirastine
  • HY-101642
    Losmiprofen 74168-08-4 98%
    Losmiprofen is a nonsteroidal antiinflammatory agent.
    Losmiprofen
  • HY-101670
    MTPPA 70991-61-6 98%
    MTPPA is a agent for treating symptoms of inflammation and pain.
    MTPPA
  • HY-101686
    LM-1484 197506-02-8 98%
    LM-1484 is an antagonist of CysLT1 receptor and displays a higher affinity for 3H-LTC4 sites.
    LM-1484
  • HY-101687
    Nosantine racemate 75166-67-5 98%
    Nosantine racemate is the racemate of Nosantine. Nosantine is an inducer of IL-2 or enhancer of IL-2 induction by phytohemagglutinin (PHA).
    Nosantine racemate
  • HY-101694
    Siltenzepine 98374-54-0 98%
    Siltenzepine (AWD 26-06 free base) is an antagonist of mAChR with anti-acid activity, which can be used in peptic ulcers research. Siltenzepine exhibits rapidly but incompletely absorbed characterastic in rats (po).
    Siltenzepine
  • HY-101698
    Alniditan 152317-89-0 98%
    Alniditan (Alnitidan) is a potent 5-HT1B and 5-HT1D receptors agonist, with IC50s of 1.7 nM and 1.3 nM for h5-HT1B and h5-HT1D receptors in HEK293 cells, respectively. Alniditan has migraine-preventive effects.
    Alniditan
  • HY-101724
    ReN-1869 hydrochloride 170149-76-5 98%
    ReN 1869 hydrochloride is a novel, selective histamine H1 receptor antagonist, which demonstrates affinity to the histamine H1 receptor (guinea pig brain) with Ki of 0.19±0.04 μM and the non-selective σ site (guinea pig brain) with Ki of 0.45 μM.
    ReN-1869 hydrochloride
  • HY-101731
    CP-96021 hydrochloride 167011-22-5 98%
    CP-96021 hydrochloride is a balanced, combined, potent and orally active leukotriene D4 (LTD4)/platelet activating factor (PAF) receptor antagonist with Ki values of 34 nM and 37 nM, respectively.
    CP-96021 hydrochloride
  • HY-101743
    Elucaine 25314-87-8 98%
    Elucaine is a muscarinic acetylcholine receptor antagonist with anti-ulcerative activity.
    Elucaine
Cat. No. Product Name / Synonyms Application Reactivity