2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N7851
    Terpineol 8000-41-7 98%
    Terpineol is a monoterpenoid alcohol compound that is widely found in plants, especially in the peels of citrus fruits. Terpineol has antioxidant, anti-inflammatory and antibacterial activities and is commonly used in the fragrance industry as an additive in food, beverages, cosmetics and perfumes.
    Terpineol
  • HY-N7937
    γ-Asarone 5353-15-1 98%
    γ-Asarone, a phenylpropene, shows strong correlation with the biological activities (anti-oxidative, anti-inflammatory and neurotrophic effects).
    γ-Asarone
  • HY-N7945
    6-Hydroxykaempferol 3-O-β-rutinoside-6-O-β-D-glucoside 145134-63-0 98%
    6-Hydroxykaempferol 3-O-β-rutinoside-6-O-β-D-glucoside is a potent antioxidant that can be isolated from Carthamus tinctorius.
    6-Hydroxykaempferol 3-O-β-rutinoside-6-O-β-D-glucoside
  • HY-N8085
    Icariside F2 115009-57-9 98%
    Icariside F2 is a potent NF-κB inhibitor with an IC50 value of 16.25 μM. Icariside F2 is an aromatic glycoside isolated from the leaves of E. ulmoides Oliver. Icariside F2 has anti-inflammatory activity.
    Icariside F2
  • HY-N8200
    Cassiaside B2 218155-40-9 98%
    Cassiaside B2 is a protein tyrosine phosphatase 1B (PTP1B) and human monoamine oxidase A (hMAO-A) inhibitor. Cassiaside B2 possesses antiallergic and is a 5-HT2C receptor agonist...
    Cassiaside B2
  • HY-N8228
    17-Hydroxyneomatrine 2306139-04-6 98%
    17-Hydroxyneomatrine, extracted from Sophora flavescens, can well inhibit the growth of human cervical carcinoma Hela cells, has the wide-range antibacterial, anti-allergy, anti-tumor, anti-arrhythmia, swelling-subsiding diuresis, immunizing, and biological regulation functions.
    17-Hydroxyneomatrine
  • HY-N8229
    7β,15α,20-Trihydroxy-3,11,23-trioxo-5α-lanosta-8-en-26-oic acid 2374206-89-8 98%
    7β,15α,20-Trihydroxy-3,11,23-trioxo-5α-lanosta-8-en-26-oic acid is a triterpenoid compound found in Ganoderma lucidum. 7β,15α,20-Trihydroxy-3,11,23-trioxo-5α-lanosta-8-en-26-oic acid may exhibit anti-inflammatory activity and holds potential for research in inflammatory diseases.
    7β,15α,20-Trihydroxy-3,11,23-trioxo-5α-lanosta-8-en-26-oic acid
  • HY-N8304
    Shegansu B 291535-65-4 98%
    Shegansu B is an inhibitor of IL-1β. Shegansu B 6 inhibits IL-1β expression on LPS-induced THP-1 cells with 64.74% inhibition. Shegansu B has anti-inflammatory activity.
    Shegansu B
  • HY-N8372
    Nalanthalide 145603-76-5 98%
    Nalanthalide is a voltage-gated potassium channel Kv1.3 blocker (IC50=3.9 µM) and a potential immunosuppressant. Nalanthalide can be used for research on inflammatory immune diseases, such as neuroinflammation.
    Nalanthalide
  • HY-N8380
    (-)-Latifolin 10154-42-4 98%
    (-)-Latifolin, a flavonoid, induces apoptotic cell death by targeting PI3K/AKT/mTOR/p70S6K signaling. (-)-Latifolin significantly inhibits the cell proliferation of oral squamous cell carcinoma (OSCC), and causes the anti-metastatic activities by effectively blocking cell migration, invasion, and adhesion via the inactivation of FAK/Src. (-)-Latifolin suppresses autophagic-related proteins and autophagosome formation. (-)-Latifolin inhibits necroptosis by dephosphorylating necroptosis-regulatory proteins (RIP1, RIP3, and MLKL). (-)-Latifolin has beneficial effects on anti-aging, anti-carcinogenic, anti-inflammatory, and cardio-protective activities.
    (-)-Latifolin
  • HY-N8541
    Endocrocin 481-70-9 98%
    Endocrocin, an anthraquinone, is a fungal secondary metabolite. Endocrocin is a potent chemotaxis inhibitor with immunosuppressive properties.
    Endocrocin
  • HY-N8579
    Eugenyl benzoate 531-26-0
    Eugenyl benzoate has the potency for scavenging of DPPH radical. Eugenyl Benzoate Derivatives can be used for development of BCL-2 inhibitors.
    Eugenyl benzoate
  • HY-N8690
    4,2'-Dihydroxy-4'-methoxychalcone 63529-06-6 98%
    4,2'-Dihydroxy-4'-methoxychalcone, a chalcone, shows allergy-preventive effects.
    4,2'-Dihydroxy-4'-methoxychalcone
  • HY-N8691
    2',6'-Dihydroxy-4'-methoxydihydrochalcone 35241-55-5 98%
    2',6'-Dihydroxy-4'-methoxydihydrochalcone is an orally active dihydrochalcone compound with antiplasmodial and anti-inflammatory activities. 2',6'-Dihydroxy-4'-methoxydihydrochalcone reduces the IL-1β, TNF, and nitrite levels in vitro.
    2',6'-Dihydroxy-4'-methoxydihydrochalcone
  • HY-N8802
    (-)-Epicatechin 3-(3-O-methylgallate) 83104-86-3 98%
    (-)-Epicatechin 3-(3-O-methylgallate) is a catechin, that can be isolated from tea leaf. (-)-Epicatechin 3-(3-O-methylgallate) shows anti-inflammatory activity.
    (-)-Epicatechin 3-(3-O-methylgallate)
  • HY-N8811
    Acetyl 11α-methoxy-β-boswellic acid 918548-43-3 98%
    Acetyl 11α-methoxy-β-boswellic acid is a terpenoid compound derived from the resin of olive plants, and it holds promise for research in fields such as anti-inflammatory, anti-cancer, and analgesic applications.
    Acetyl 11α-methoxy-β-boswellic acid
  • HY-N8818
    3-Acetoxytirucalla-7,24-dien-21-oic acid 98166-55-3 98%
    3-Acetoxytirucalla-7,24-dien-21-oic acid, derived from Boswellia carteri, exhibits anti-inflammatory activity. Its ID50 for Phorbol 12-myristate 13-acetate (HY-18739)-induced ear swelling in mice is 0.06 mg per ear. 3-Acetoxytirucalla-7,24-dien-21-oic acid holds potential for research in the field of inflammation.
    3-Acetoxytirucalla-7,24-dien-21-oic acid
  • HY-N8862
    Anti-inflammatory agent 69 80514-14-3 98%
    Anti-inflammatory agent 69 (compound 12), sesquiterpenoid, is an anti-inflammatory agent isolated from the dried flower buds of Tussilago farfara. Anti-inflammatory agent 69 can inhibit the NO production with IC50 value of 24 μM.
    Anti-inflammatory agent 69
  • HY-N9104
    ent-Labda-8(17),13Z-diene-15,16,19-triol 19-O-glucoside 1245636-01-4 98%
    ent-Labda-8(17),13Z-diene-15,16,19-triol 19-O-glucoside is a natural product derived from the leaves of Andrographis paniculata that has anti-inflammatory and antiviral activity.
    ent-Labda-8(17),13Z-diene-15,16,19-triol 19-O-glucoside
  • HY-N9260
    4E-Deacetylchromolaenide 4'-O-acetate 104736-09-6 98%
    4E-Deacetylchromolaenide 4'-O-acetate (Compound 11) is a sesquiterpenoid that can be isolated fromEupatorium chinense L..
    4E-Deacetylchromolaenide 4'-O-acetate
Cat. No. Product Name / Synonyms Application Reactivity