2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N1230
    Sophoraisoflavone A 117204-81-6 98%
    Sophoraisoflavone A (Allolicoisoflavone B) is a nature product that could be isolated from Glycyrrhiza inflate. Sophoraisoflavone A is a potent protein tyrosine phosphatase 1B (PTP1B) inhibitor with an IC50 value of 0.80 μM. Sophoraisoflavone A can be used in research of inflammation.
    Sophoraisoflavone A
  • HY-N1253
    Scoparinol 130838-00-5 98%
    Scoparinol (Scopadiol) is a diterpene isolated from Scoparia dulcis that has significant analgesic and anti-inflammatory activities.
    Scoparinol
  • HY-N1330
    Rubranol 211126-61-3 98%
    Rubranol is an inhibitor of NO Synthase. Rubranol inhibits LPS-induced NO production in activated macrophages with 74% inhibition.
    Rubranol
  • HY-N1695
    Demethylregelin 173991-81-6 98%
    Demethylregelin (Regelin acid), a triterpene, effectively reduces the expression of iNOS protein and subsequent nitric oxide production induced by lipopolysaccharide (HY-D1056) in RAW264.7 cells. Demethylregelin has anti-inflammatory activities.
    Demethylregelin
  • HY-N1875
    4-(Ethoxymethyl)phenol 57726-26-8 98.02%
    4-(Ethoxymethyl)phenol (p-Hydroxybenzyl Et ether) is a potent antioxidant from Amburana cearensis leaf extract, with in vitro cytogenotoxic properties. Amburana cearensis leaves can be used foe the research of respiratory diseases and inflammations.
    4-(Ethoxymethyl)phenol
  • HY-N2021
    Phosphoramidon 36357-77-4 98%
    Phosphoramidon, a microbial metabolite, is a specific metalloprotease thermolysin inhibitor with an IC50 of 0.4 μg/mL. Phosphoramidon also inhibits endothelin-converting enzyme (ECE), neutral endopeptidase (NEP), and angiotensin-converting enzyme (ACE) with IC50 values of 3.5, 0.034, and 78 μM, respectively.
    Phosphoramidon
  • HY-N2220
    6-Formyl-isoophiopogonanone A 116291-82-8 98%
    6-Formyl-isoophiopogonanone A is a homoisoflavonoidal extracted from Ophiopogon japonicas, with antioxidant activity.
    6-Formyl-isoophiopogonanone A
  • HY-N2351
    Paeonoside 20309-70-0 98%
    Paeonoside is a bioactive compound identified in P. suffruticosa that promotes wound healing and migration in osteoblast differentiation. Paeonoside has also been reported to have some antidiabetic activity and may prevent sepsis-induced lethality.
    Paeonoside
  • HY-N2545
    Tenacissoside X 875057-87-7 98%
    Tenacissoside X (Tenacissoside J) is a compound isolated from Marsdenia tenacissima. Marsdenia tenacissima, a traditional Chinese herbal medicine, has long been used for the research of asthma, tracheitis, rheumatism, etc.
    Tenacissoside X
  • HY-N2643
    4-Oxobedfordiaic acid 68799-38-2 98%
    4-Oxobedfordiaic acid is an orally active natural product, that can be isolated from Xanthium cavanillesi. 4-Oxobedfordiaic acid shows anti-ulcerogenic activity.
    4-Oxobedfordiaic acid
  • HY-N2794
    9-Hydroxy-α-lapachone 22333-58-0 98%
    9-Hydroxy-α-lapachone (α-Dihydrocaryopterone) is a natural phenol, exhibits potent inhibitory effects with an IC50 of 4.64 µM on LPS-induced NO production in RAW 264.7 cells.
    9-Hydroxy-α-lapachone
  • HY-N2940
    Bisandrographolide A 160498-00-0 98%
    Bisandrographolide A (BAA) activates TRPV4 channel with an EC50 of 790-950 nM. Bisandrographolide A can bind to CD81 and suppress its function. Bisandrographolide A is an anti-inflammatory, immunostimulant, and antihypertensive compound.
    Bisandrographolide A
  • HY-N3185
    N-Methylcalycinine 86537-66-8 98%
    N-Methylcalycinine is a nature product with AChE inhibitory activity. N-Methylcalycinine can be isolated from the roots of Stephania epigaea. N-Methylcalycinine can be used for the research of asthma, cancer, dysentery, fever, hyperglycemia, intestinal complaints, inflammation, sleep disturbances, tuberculosis and so on.
    N-Methylcalycinine
  • HY-N3211
    N-cis-Feruloyl tyramine 80510-09-4 98%
    N-cis-Feruloyl tyramine (cis-N-(4-Hydroxyphenethyl) ferulamide) is a natural phenolic compound, exhibits modest inhibitory activity on LPS-activated NO production in RAW 264.7 cells.
    N-cis-Feruloyl tyramine
  • HY-N3261
    Methyllinderone 3984-73-4 98%
    Methyllinderone is an inhibitor of AP-1/STAT/ERK. Methyllinderone has anti-inflammatory effect. Methyllinderone reduce the invasion and migration rate of TPA-stimulated MCF-7 cells. Methyllinderone can be used in study breast cancer metastasis.
    Methyllinderone
  • HY-N3310
    Mearnsetin 16805-10-0 98%
    Mearnsetin is a compound that can be isolated from Elaeocarpus lanceofolius. Mearnsetin has antioxidative properties.
    Mearnsetin
  • HY-N3548
    Catalpalactone 1585-68-8 98%
    Catalpalactone has anti-inflammatory effect. Catalpalactone inhibits LPS-induced NO production and iNOS expression in RAW264.7 cells, and also inhibits IRF3, NF-κB, and IFN-β/STAT-1 activation. Catalpalactone also inhibits dopamine biosynthesis by reducing tyrosine hydroxylase (TH) and aromatic-l-amino acid decarboxylase (AADC) activities.
    Catalpalactone
  • HY-N3566
    Cepharadione A 55610-01-0 98%
    Cepharadione A can be isolated from the roots of Piper betle Linn. Cepharadione A inhibits FMLP/CB induced elastase release by human neutrophils.
    Cepharadione A
  • HY-N3596
    Cleomiscosin C 84575-10-0 98%
    Cleomiscosin C (Aquillochin) can be isolated from Aquilaria agallocha. Cleomiscosin C has antioxidant activity. Cleomiscosin C inhibits LDL oxidation and free radicals generation.
    Cleomiscosin C
  • HY-N3622
    Corchoionoside C 185414-25-9 98%
    Corchoionoside C ((6S,9S)-Roseoside), an ionone glucoside, can be isolated from Capparis spinosa. Corchoionoside C inhibits the antigen-antibody reaction induced histamine release from rat peritoneal exudate cells.
    Corchoionoside C
Cat. No. Product Name / Synonyms Application Reactivity