2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-NP083A
    Wisteria Floribunda Lectin (Biotin) 98%
    Wisteria Floribunda Lectin (Biotin) (WFA (Biotin)) is a biotinylated lectin with affinity for N-acetyl-D-galactosamine.
    Wisteria Floribunda Lectin (Biotin)
  • HY-NP158I
    Collagen Type II (undenatured)
    Collagen Type II (undenatured) is a T-cell dependent antigen with unique immunological features. Type II Collagen, T Cell Grade, from Bovine can be used as a stimulating antigen for T-cells in in vitro culture systems.
    Collagen Type II (undenatured)
  • HY-NP179B
    Pollen extract,ragweed
    Pollen extract,ragweed is an allergen extracted from ragweed samples and can be used as an allergen in allergy research.
    Pollen extract,ragweed
  • HY-NP182A
    Folic acid-BSA
    Folic acid-BSA (FA-BSA) is a conjugate of Folic acid (HY-16637) and BSA that improves the stability and solubility of Folic acid.
    Folic acid-BSA
  • HY-NP189H
    Human IgG Fab fragment
    Human IgG Fab fragment is a fragment of antigen (Fab) of human immunoglobulin G (IgG) molecules that can be used as an immunolabel in various immunoassays, including ELISA.
    Human IgG Fab fragment
  • HY-NP193A
    Rat IgG Fc fragment 98%
    Rat IgG Fc fragment is a crystallizable fragment (Fc) of rat immunoglobulin G (IgG) molecules that can be used as an immunolabel in various immunoassays, including ELISA.
    Rat IgG Fc fragment
  • HY-NP193B
    Rat IgG Fab fragment
    Rat IgG Fab fragment is a fragment of antigen (Fab) of rat immunoglobulin G (IgG) molecules that can be used as an immunolabel in various immunoassays, including ELISA.
    Rat IgG Fab fragment
  • HY-NP194A
    Cyclosporin A-OVA
    Cyclosporin A-OVA is a conjugate of Cyclosporin A (HY-B0579) and OVA. Cyclosporin A is an immunosuppressant which binds to the cyclophilin .
    Cyclosporin A-OVA
  • HY-NP194B
    Cyclosporin A-KLH
    Cyclosporin A-KLH is a conjugate of Cyclosporin A (HY-B0579) and KLH. Cyclosporin A is an immunosuppressant which binds to the cyclophilin .
    Cyclosporin A-KLH
  • HY-NP202A
    C3 Protein (human)
    C3 Protein (human) is a naturally glycosylated polypeptide containing two disulfide-linked chains. Complement protein C3 is a central molecule in the complement system whose activation is essential for all the important functions performed by this system.
    C3 Protein (human)
  • HY-NP202B
    C4 Protein (human)
    C4 Protein (human) is a naturally occurring glycosylated polypeptide with three disulfide-linked chains. C4 is the activation center of both the classical and lectin pathways of complement activation.
    C4 Protein (human)
  • HY-NP202C
    C5 Protein (human)
    C5 Protein (human) is a naturally occurring glycosylated polypeptide containing two disulfide-linked chains. C5 is essential for the formation of the membrane attack complex (MAC) and is activated by all three pathways of complement activation.
    C5 Protein (human)
  • HY-P0018C
    Pepstatin acetate 28575-34-0 98%
    Pepstatin (Pepstatin A) acetate is a specific, orally active aspartic protease inhibitor produced by actinomycetes, with IC50s of 4.5 nM, 6.2 nM, 150 nM, 290 nM, 520 nM and 260 nM for hemoglobin-pepsin, hemoglobin-proctase, casein-pepsin, casein-proctase, casein-acid protease and hemoglobin-acid protease, respectively. Pepstatin acetate also inhibits HIV protease.
    Pepstatin acetate
  • HY-P0018R
    Pepstatin (Standard) 26305-03-3 98%
    Pepstatin (Standard) is the analytical standard of Pepstatin. This product is intended for research and analytical applications. Pepstatin (Pepstatin A) is a specific, orally active aspartic protease inhibitor produced by actinomycetes, with IC50s of 4.5 nM, 6.2 nM, 150 nM, 290 nM, 520 nM and 260 nM for hemoglobin-pepsin, hemoglobin-proctase, casein-pepsin, casein-proctase, casein-acid protease and hemoglobin-acid protease, respectively. Pepstatin also inhibits HIV protease[1][2].
    Pepstatin (Standard)
  • HY-P0036A
    Octreotide dihydrochloride 1607842-55-6 98%
    Octreotide (SMS 201-995) hydrochloride is a somatostatin receptor agonist and synthetic octapeptide endogenous somatostatin analogue. Octreotide hydrochloride can bind to the somatostatin receptors which are mainly subtypes 2, 3 and 5. Octreotide hydrochloride increases Gi activity and reduces intracellular cAMP production. Octreotide hydrochloride has antitumor activity, mediates apoptosis and may also be used in disease studies in acromegaly.
    Octreotide dihydrochloride
  • HY-P0036B
    Octreotide pamoate 135467-16-2 98%
    Octreotide (SMS 201-995) pamoate is a somatostatin receptor agonist and synthetic octapeptide endogenous somatostatin analogue. Octreotide pamoate can bind to the somatostatin receptors which are mainly subtypes 2, 3 and 5. Octreotide pamoate increases Gi activity and reduces intracellular cAMP production. Octreotide pamoate has antitumor activity, mediates apoptosis and may also be used in disease studies in acromegaly.
    Octreotide pamoate
  • HY-P0205A
    Saralasin acetate hydrate 39698-78-7 98%
    Saralasin ([Sar1,Ala8] Angiotensin II) acetate hydrate is an octapeptide analog of angiotensin II. Saralasin acetate hydrate is a competitive angiotensin II receptor antagonist with a Ki value of 0.32 nM for 74% of the binding sites, and has partial agonist activity as well. Saralasin acetate hydrate can be used for the research of renovascular hypertension, renin-dependent (angiotensinogenic) hypertension.
    Saralasin acetate hydrate
  • HY-P0295A
    Gly-Arg-Gly-Asp-Ser TFA 2828433-23-2 98%
    Gly-Arg-Gly-Asp-Ser (TFA) is a pentapeptide that forms the cell-binding domain of a glycoprotein, osteopontin. Gly-Arg-Gly-Asp-Ser binds to integrin receptors αvβ3 and αvβ5 with estimated IC50 of ∼5 and ∼6.5 μM.
    Gly-Arg-Gly-Asp-Ser TFA
  • HY-P10021
    Tapderimotide 1221082-45-6 98%
    Tapderimotide (hTERT (691–705)) is an immunological agent for active immunization.
    Tapderimotide
  • HY-P10048
    TAT-JIP 1623722-15-5 98%
    TAT-JIP inhibits the phosphorylation of endogenous c-jun activated by PHA–PMA.
    TAT-JIP
Cat. No. Product Name / Synonyms Application Reactivity