2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

Related Products

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-19041
    CGP-35949 sodium 111130-13-3 98%
    CGP-35949 sodium is a LTD4 antagonist with phospholipase inhibitory activity. CGP-35949 sodium can be used for research of asthma.
    CGP-35949 sodium
  • HY-19084
    Ro-24-0238 120555-31-9 98%
    Ro-24-0238 is an antagonist of platelet activating factor (PAF) and inhibitor of thromboxane synthesis, used for lessening the inflammation and damage resulting from a local release of PAF.
    Ro-24-0238
  • HY-19153
    Nepaprazole 156601-79-5 98%
    Nepaprazole (rel-TY-11345 free base) is a proton pump inhibitor. Nepaprazole inhibits H+/K+-ATPase activity in isolated rabbit gastric mucosal microsomes with the IC50 values of 5.8 μM and 9.9 μM at pH 6.0 and pH 7.4, respectively. Nepaprazole can be used for study of peptic ulcer diseases.
    Nepaprazole
  • HY-19167
    Ecraprost 136892-64-3 98%
    Ecraprost is a prodrug of prostaglandin E1. Ecraprost inhibits platelet adhesion, macrophage infiltration and proliferating cell nuclear antigen positive cell expression on the injured arterial walls.
    Ecraprost
  • HY-19212
    S-2474 158089-95-3 98%
    S-2474 is an inhibitor of COX-2 and 5-lipoxygenase (5-LO), with IC50s of 11 nM and 27 μM for COX-2 and COX-1 in human intact cells, and used as a nonsteroidal anti-inflammatory agent.
    S-2474
  • HY-19217
    Thioflosulide 158205-05-1 98%
    Thioflosulide (L-745337) is a selective cyclooxygenase-2 (COX2) inhibitor, with an IC50 of 2.3 nM, and shows anti-inflammatory activity.
    Thioflosulide
  • HY-19218
    RPR-106541 159001-35-1 98%
    RPR-106541 is a 17-thiosteroid. RPR 106541 has potent glucocorticosteroid activity. RPR 106541 also has demonstrable effects on carbohydrate and lipid metabolism.
    RPR-106541
  • HY-19393
    SCH 351591 444659-43-2 98%
    SCH 351591 is a potent, selective and orally active phosphodiesterase-4 (PDE4) inhibitor with an IC50 of 58 nM. SCH 351591 can inhibit all 4 PDE4 subtypes (A, B, C, and D). SCH 351591 has the potential for the asthma and chronic obstructive pulmonary disease (COPD) research.
    SCH 351591
  • HY-19814
    Toripristone 91935-26-1 98%
    Toripristone (RU-40555) is a cortisol receptor inhibitor. Toripristone combined with clarithromycin can increase the antibacterial activity of Mycobacterium avium complex infection.
    Toripristone
  • HY-19920
    AVX001 300553-18-8 98%
    AVX001 is an inhibitor of phospholipase A2 (cPLA2α) that can be used in the research of psoriasis.
    AVX001
  • HY-20070
    BMS-566394 503166-51-6 98%
    BMS-566394 is a potent inhibitor of tumor necrosis factor-α (TNF-α) converting enzyme (TACE) that helps reduce the production of TNF-α, thereby alleviating inflammation and immune-mediated diseases and can be used in the study of inflammatory and autoimmune diseases.
    BMS-566394
  • HY-23499
    Indeno[1,2,3-cd]pyrene 193-39-5
    Indeno[1,2,3-cd]pyrene is a polycyclic aromatic hydrocarbon with moderate cytotoxicity in human pulmonary alveolar epithelial cells HPAEpiC. Indeno[1,2,3-cd]pyrene enhances allergic lung infammation via aryl hydrocarbon receptor.
    Indeno[1,2,3-cd]pyrene
  • HY-29268
    β-Carboline-1-carboxylic acid 26052-96-0 98%
    β-Carboline 1-carboxylic acid is a β-carboline alkaloid with anti-inflammatory, antifibrotic, antitumor and antibacterial activities. β-Carboline 1-carboxylic acid is the cAMP phosphodiesterase (IC50: 96 µM) and indoleamine 2, 3-dioxygenase (IDO) inhibitor. β-Carboline 1-carboxylic acid is cytotoxic to tumor cells. β-Carboline 1-carboxylic acid inhibits inflammation through the NF-κb/p65 pathway and can reverse epithelial-mesenchymal transition (EMT). In addition, β-Carboline 1-carboxylic acid has strong inhibitory activity against S. aureus (IC50: 47.70 μg/mL) and E. coli (IC50: 19.17 μg/mL).
    β-Carboline-1-carboxylic acid
  • HY-30235
    Benzydamine 642-72-8 98%
    Benzydamine is an orally administered prostaglandin synthesis inhibitor that has anti-inflammatory, analgesic, antipyretic, and antibacterial properties. Benzydamine can inhibit TNF-α, stabilize cell membranes, and reduce oxidative stress within cells.
    Benzydamine
  • HY-32088
    Ethyl 10-bromodecanoate 55099-31-5
    Ethyl 10-bromodecanoate is an antiinflammatory and hemostatic agent. Ethyl 10-bromodecanoate is a member of the family of linolenic acid, which includes diethyl succinate and ethyl palmitate. Ethyl 10-bromodecanoate has been shown to have antibacterial properties.
    Ethyl 10-bromodecanoate
  • HY-45826
    MRX343 1112968-16-7 98.37%
    MRX343 is a metabolite of MRX-I (HY-19915).
    MRX343
  • HY-47709
    STING ligand-3 2762552-73-6 98%
    STING ligand-3 is a Ligand for Target Protein for PROTAC activity control. STING ligand-3 can be used to synthesize Anti-inflammatory agent 70 (HY-157570).
    STING ligand-3
  • HY-50692
    CAY10734 635701-59-6 98%
    CAY10734 is the agonist for sphingosine-1-phosphate receptor 1 (S1P1) with an IC50 of 1.3 nM. CAY10734 promotes the recirculation of peripheral blood lymphocytes, and is a potential immunosuppressant.
    CAY10734
  • HY-69172
    RS-25344 152814-89-6 98%
    RS-25344 is a selective inhibitor of phosphodiesterase type IV (PDE4). RS-25344 increases intracellular cAMP (cyclic adenosine phosphate) concentration by inhibiting PDE4 activity. RS-25344 can be used in the study of inflammation, immune diseases, neurodegenerative diseases and cardiovascular diseases.
    RS-25344
  • HY-70050
    Alosetron (Hydrochloride(1:X)) 132414-02-9 98%
    Alosetron (GR 68755) Hydrochloride(1:X) is a potent and highly selective serotonin 5-HT3 receptor antagonist. Alosetron Hydrochloride(1:X) is used for the research of irritable bowel syndrome (IBS). Alosetron Hydrochloride(1:X) blocks the fast 5HT3-mediated depolarisation of guinea-pig myenteric and submucosal neurons, with IC50 at ~55 nM. Alosetron Hydrochloride(1:X) attenuates the visceral nociceptive effect of rectal distension in conscious or anaesthetised dogs. Anti-inflammatory effects.
    Alosetron (Hydrochloride(1:X))
Cat. No. Product Name / Synonyms Application Reactivity