1. Inflammation/Immunology

Inflammation/Immunology

The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-W018772S1
    D-Ribose-13C 70849-24-0 98%
    D-Ribose-13C is the 13C labeled D-Ribose. D-Ribose is an energy enhancer, and acts as a sugar moiety of ATP, and widely used as a metabolic therapy supplement for chronic fatigue syndrome or cardiac energy metabolism. D-Ribose is active in protein glycati
    D-Ribose-13C
  • HY-W018772S2
    D-Ribose-13C-1 83379-40-2 98%
    D-Ribose-13C-1 is the 13C labeled D-Ribose. D-Ribose is an energy enhancer, and acts as a sugar moiety of ATP, and widely used as a metabolic therapy supplement for chronic fatigue syndrome or cardiac energy metabolism. D-Ribose is active in protein glyca
    D-Ribose-13C-1
  • HY-W018772S3
    D-Ribose-13C-2 211947-12-5 98%
    D-Ribose-13C-2 is the 13C labeled D-Ribose. D-Ribose is an energy enhancer, and acts as a sugar moiety of ATP, and widely used as a metabolic therapy supplement for chronic fatigue syndrome or cardiac energy metabolism. D-Ribose is active in protein glyca
    D-Ribose-13C-2
  • HY-W018772S4
    D-Ribose-13C-3 139657-62-8 98%
    D-Ribose-13C-3 is the 13C labeled D-Ribose. D-Ribose is an energy enhancer, and acts as a sugar moiety of ATP, and widely used as a metabolic therapy supplement for chronic fatigue syndrome or cardiac energy metabolism. D-Ribose is active in protein glyca
    D-Ribose-13C-3
  • HY-W018772S5
    D-Ribose-13C-4 ≥99.0%
    D-Ribose-13C-4 is the 13C labeled D-Ribose. D-Ribose is an energy enhancer, and acts as a sugar moiety of ATP, and widely used as a metabolic therapy supplement for chronic fatigue syndrome or cardiac energy metabolism. D-Ribose is active in protein glyca
    D-Ribose-13C-4
  • HY-W018772S6
    D-Ribose-d 119540-50-0 98%
    D-Ribose-d is the deuterium labeled D-Ribose. D-Ribose is an energy enhancer, and acts as a sugar moiety of ATP, and widely used as a metabolic therapy supplement for chronic fatigue syndrome or cardiac energy metabolism. D-Ribose is active in protein gly
    D-Ribose-d
  • HY-W018772S7
    D-Ribose-d-1 202480-69-1 98%
    D-Ribose-d-1 is the deuterium labeled D-Ribose. D-Ribose is an energy enhancer, and acts as a sugar moiety of ATP, and widely used as a metabolic therapy supplement for chronic fatigue syndrome or cardiac energy metabolism. D-Ribose is active in protein g
    D-Ribose-d-1
  • HY-W018772S8
    D-Ribose-d-2 169783-76-0 98%
    D-Ribose-d-2 is the deuterium labeled D-Ribose. D-Ribose is an energy enhancer, and acts as a sugar moiety of ATP, and widely used as a metabolic therapy supplement for chronic fatigue syndrome or cardiac energy metabolism. D-Ribose is active in protein g
    D-Ribose-d-2
  • HY-W018772S9
    D-Ribose-d-3 478506-29-5 98%
    D-Ribose-d-3 is the deuterium labeled D-Ribose. D-Ribose is an energy enhancer, and acts as a sugar moiety of ATP, and widely used as a metabolic therapy supplement for chronic fatigue syndrome or cardiac energy metabolism. D-Ribose is active in protein g
    D-Ribose-d-3
  • HY-W067056S1
    Methyl(E)-cinnamate-d7 2022152-96-9 98%
    Methyl(E)-cinnamate-d7 is the deuterium labeled Methyl (E)-cinnamate. Methyl (E)-cinnamate (EMC), a phytochemical constituent isolated from Alpinia katsumadai Hayata, is a natural flavor compound with anti-inflammatory properties. Methyl (E)-cinnamate is widely used in the food and commodity industry.
    Methyl(E)-cinnamate-d7
  • HY-W018772S16
    D-Ribose-1,2-13C2 209909-88-6 98%
    D-Ribose-1,2-13C2 is the 13C labled D-Ribose(mixture of isomers) (HY-W018772). D-Ribose(mixture of isomers) is an energy enhancer,and acts as a sugar moiety of ATP,and widely used as a metabolic therapy supplement for chronic fatigue syndrome or cardiac energy metabolism. D-Ribose(mixture of isomers) is active in protein glycation,induces NF-κB inflammation in a RAGE-dependent manner.
    D-Ribose-1,2-13C2
  • HY-12348
    LEO 29102 1035572-38-3 98%
    LEO 29102 is a potent phosphodiesterase 4 (PDE4) inhibitor with an IC50 value of 5 nM. LEO 29102 inhibits TNFα release. LEO 29102 has the potential for the research of atopic dermatitis.
    LEO 29102
  • HY-12517
    GNE-293 1354955-67-1 98%
    GNE-293 is a potent and selective PI3Kδ inhibitor (IC50 = 4.38 nM). GNE-293 has favorable pharmacokinetic properties. GNE-293 can be used for research of asthma, rheumatoid arthritis, and other inflammatory disorders.
    GNE-293
  • HY-12733
    AZD5248 1254318-44-9 98%
    AZD5248 is a dipeptidyl peptidase 1 (DPP1) inhibitor that can be used for the research of chronic obstructive lung disease.
    AZD5248
  • HY-12900
    RB-005 1425049-20-2 98%
    RB-005 is a selective inhibitor of sphingosine kinase 1 (SK1) (IC50=3.6 µM), with weaker inhibition of another isoenzyme, SK2. The selective inhibition of RB-005 helps to distinguish the biological functions and roles of SK1 and SK2, which can be used in the study of inflammatory diseases and cancer.
    RB-005
  • HY-13475
    mPGES1-IN-8 1381846-21-4 98%
    mPGES1-IN-8, is a novel microsomal prostaglandin E synthase 1 (mPGES1) inhibitor.
    mPGES1-IN-8
  • HY-13496
    JNJ-28312141 885692-52-4 98%
    JNJ-28312141 is an inhibitor for colony-stimulating factor-1 receptor (CSF-1R or FMS), with an IC50 of 0.69 nM. JNJ-28312141 inhibits proliferation of BDBM, MV-4-11, M-o7e, TF-1 with an IC50s of 2.6, 21, 41 and 150 nM, respectively. JNJ-28312141 exhibits anti-inflammatory activity in mouse arthritis model.
    JNJ-28312141
  • HY-14135
    BMS 488043 452296-83-2 98%
    BMS 488043 (BMS 043) is an orally active and well-tolerated inhibitor of the attachment of human immunodeficiency virus type 1 (HIV-1) to CD4+ lymphocytes.
    BMS 488043
  • HY-14155
    MMP145 1025717-75-2 98%
    MMP145 (compound 27) is a potent, selective and orally active MMP-12 inhibitor. MMP145 is effective in inflammation and asthma reasearch.
    MMP145
  • HY-14162
    AM103 free acid 936349-47-2 98%
    AM103 (free acid) is a selective FLAP inhibitor that can block the first step of the LT pathway, which is 5-LO activation. AM103 (free acid) can inhibit the production of LTB4 and cysteinyl leukotrienes (CysLT). AM103 (free acid) has anti-inflammatory activity in a mouse model of chronic lung inflammation and can extend the survival time of mice injected with platelet-activating factor. AM103 (free acid) can be used for research on respiratory diseases such as asthma.
    AM103 free acid
Cat. No. Product Name / Synonyms Application Reactivity