2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-N12648
    Anemarsaponin E1 1276608-19-5 98%
    Anemarsaponin E1 can be isolated from Guizhi-Shaoyao-Zhimu decoction (GSZD), and can be used for research of rheumatoid arthritis (RA), gout, osteoarthritis, etc.
    Anemarsaponin E1
  • HY-N12649
    Timosaponin E2 222018-47-5 98%
    Timosaponin E2 is an antiinflammatory agent, and inhibits active oxygen production.
    Timosaponin E2
  • HY-N12694
    3-O-Methylellagic acid-4′-O-α-L-rhamnopyranoside 51768-39-9 98%
    3-O-Methylellagic acid-4′-O-α-L-rhamnopyranoside is an ellagic acid glycoside compound that can be isolated from the stem bark of Aphananthe aspera and can be used for the research of inflammation and pain.
    3-O-Methylellagic acid-4′-O-α-L-rhamnopyranoside
  • HY-N12703
    N-Acetyldopamine dimmers A 1519015-73-6 98%
    N-Acetyldopamine dimmers A (Compound (+)-2) can be isolated from the cast-off shell of the cicada of Cryptotympana sp. N-Acetyldopamine dimmers A increases collagen and α-SMA expression.
    N-Acetyldopamine dimmers A
  • HY-N12707
    Kadsurenin C 145722-88-9 98%
    Kadsurenin C (compound 1) is a neolignan that can be isolated from the aerial part of Piper kadsura with anti-inflammation activity. Kadsurenin C exhibits significant PAF (Platelet Activating Factor) antagonistic activity with IC50 value of 5.1 μM.
    Kadsurenin C
  • HY-N12726
    Halociline 2977255-36-8 98%
    Halociline, a derivative of alkaloids, that can be isolated from the marine fungus Penicillium griseofulvum. Halociline targets MAPK1, MMP-9, and PIK3CA in gastric cancer cells, potentially mediated by diverse pathways including cancer, lipid metabolism, atherosclerosis, and EGFR tyrosine kinase inhibitor resistance. Halociline possesses antimicrobial, antioxidant and biofilm inhibitory activities.
    Halociline
  • HY-N12737
    15-epi-Danshenol A 216987-13-2 98%
    15-epi-Danshenol A is a diterpenoid with an immune-modulating activity. 15-epi-Danshenol A shows inhibitory effect on B lymphoblasts cells in a concentration-dependent manner.
    15-epi-Danshenol A
  • HY-N12742
    Tamarixetin 3-O-β-d-apiofuranosyl-(1 → 2)-β-d-galactopyranoside 98%
    Tamarixetin 3-O-β-d-apiofuranosyl-(1 → 2)-β-d-galactopyranoside (compound 4) is an inhibitor of collagenase and elastase with potential anti-inflammatory activity. Tamarixetin 3-O-β-d-apiofuranosyl-(1 → 2)-β-d-galactopyranoside can be isolated from the methanol extract of the Balkan endemic species Astragalus thracicus Griseb.
    Tamarixetin 3-O-β-d-apiofuranosyl-(1 → 2)-β-d-galactopyranoside
  • HY-N12743
    Farobin A 1245447-08-8 98%
    Farobin A is a natural compound with antibacterial, antioxidant and anti-inflammatory activities. Farobin A against Streptococcus mutans ATCC 25175 and Streptococcus sobrinus ATCC 33478. Farobin A shows anti-inflammatory activity on cytokine IL-6 and TNF-α.
    Farobin A
  • HY-N12761
    Penpaxilloids A 98%
    Penpaxilloids A (Compound 1) is a non-competitive inhibitor of protein tyrosine phosphatase 1B (PTP1B) with an IC50 value of 8.60 μM. Penpaxilloids A can be isolated from the fungus Penicillium sp. ZYX-Z-143. Penpaxilloids A is also an α-glucosidase (α-glucosidase) inhibitor with anti-inflammatory activity.
    Penpaxilloids A
  • HY-N12767
    Salixteroside D 98%
    Salixteroside D is a salicin derivative, that exhibits anti-inflammatory activity through inhibition of MAPK and NF-κB signaling pathways.
    Salixteroside D
  • HY-N12817
    Anti-inflammatory agent 80 2128277-55-2 98%
    Anti-inflammatory agent 80 (Compound 2/2f) is an anti-inflammatory agent and has anti-tumor activity. Anti-inflammatory agent 80 can be isolated fromCynanchum limprichtiiSchltr.
    Anti-inflammatory agent 80
  • HY-N12834
    Ecdysoside B 1887196-18-0 98%
    Ecdysoside B (compound 6b) is a pregnanoside compound isolated from the plant Ecdysanthera rosea. Ecdysoside B and its derivatives and isomers shows anticancer, immunosuppressive and anti-inflammatory activities. Ecdysoside B shows cytotoxicity to a variety of human tumor cell lines, including PANC-1 (human pancreatic cancer cells), A375 (human melanoma cells) and U87 (brain glioma U87 cells). Ecdysoside B can be used for research in the areas of cancer, immunomodulation and anti-inflammato.
    Ecdysoside B
  • HY-N12837
    8-Epiloganin 79172-04-6 98%
    8-Epiloganin can be isolated from Castilleja rubra and has anti-inflammatory properties. 8-Epiloganin inhibits LPS-induced release of pro-inflammatory cytokines, namely tumor necrosis factor-α and interleukin-1β.
    8-Epiloganin
  • HY-N12862
    Floramanoside A 1487423-38-0 98%
    Floramanoside A is a flavonol glycoside that can be isolated from the flowers of Abelmouschus manihot. Floramanoside A has DPPH scavenging (IC50: 10.1 μM) and aldose reductase inhibition activities (IC50: 17.8 μM).
    Floramanoside A
  • HY-N12941
    Macarangin 129385-65-5 98%
    Macarangin can be isolated from propolis. Macarangin has DPPH radical-scavenging activity and shows anti-inflammatory activities via inhibiting the activation process of NLRP3 inflammasome.
    Macarangin
  • HY-N12988
    Dihydrobonducellin 103680-87-1 98%
    Dihydrobonducellin (compound 5) is a an immunomodulator. Dihydrobonducellin inhibits cell groth and the production of IL-2 and IFN-γ in PBMC cells.
    Dihydrobonducellin
  • HY-N13038
    Isovitexin-7-O-[6-feruloyl]-glucoside-4'-O-glucoside 1016970-92-5 98%
    Isovitexin-7-O-[6-feruloyl]-glucoside-4'-O-glucoside is an anti-inflammatory agent isolated from barley (Hordeum vulgare L.) leaves.
    Isovitexin-7-O-[6-feruloyl]-glucoside-4'-O-glucoside
  • HY-N13040
    Isoscoparin-7-O-glucoside 50307-26-1 98%
    Isoscoparin-7-O-glucoside is a flavonoid compound found in barley leaves. The total phenolic content (TPC) of isoscoparin-7-O-glucoside is positively correlated with COX-2 inhibitory activity, indicating anti-inflammatory activity. Isoscoparin-7-O-glucoside can be used in the study of inflammation.
    Isoscoparin-7-O-glucoside
  • HY-N13138
    Angulasaponin B 1628031-59-3 98%
    Angulasaponin B, a natural product, can be obtained from Vigna angularis. Angulasaponin B inhibits nitric oxide production in LPS-activated RAW264.7 macrophages with IC50 values ​​ranging from 13 μM to 24 μM.
    Angulasaponin B
Cat. No. Product Name / Synonyms Application Reactivity