1. Inflammation/Immunology

Inflammation/Immunology

The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-W140760
    Ceftriaxone sodium 958633-51-7 98%
    Ceftriaxone sodium is a versatile broad-spectrum β-lactam tertiary cephalosporin antibiotic that exhibits anti-inflammatory, antitumor, antibacterial, and antioxidant properties, and functions as a covalent inhibitor of GSK3β and Aurora B, making it valuable in research related to sepsis and infective endocarditis.
    Ceftriaxone sodium
  • HY-W140799
    Dichloroxylenol 133-53-9
    Dichloroxylenol is a bactericide, preservative and deodorant. Dichloroxylenol can be used for the research of endometritis and cervicitis in Holstein cows.
    Dichloroxylenol
  • HY-W145690
    Blood group A pentasaccharide 50624-46-9 98%
    Blood group A pentasaccharide (A-Pentasaccharide), an oligosaccharide in urine, can inhibit the binding of anti-A antibody to blood group A substance.
    Blood group A pentasaccharide
  • HY-W173220
    Clopirac 42779-82-8 98%
    Clopirac is a potent and orally active inhibitor of prostaglandin synthetase. Clopirac is an anti-inflammatory agent.
    Clopirac
  • HY-W182770
    GPR84 agonist-1 489403-70-5 98%
    GPR84 agonist-1 (Compound LY214-5) is a GPR84 agonist, with an EC50 of 2.479 μM. GPR84 agonist-1 can be used for the research of septicemia.
    GPR84 agonist-1
  • HY-W186242
    PDE4-IN-16 223500-15-0 98%
    PDE4-IN-16 (compound 27) is a PDE4 inhibitor with an IC50 value of 3.61 μM. PDE4-IN-16 can be used for the research of inflammatory diseases and central nervous system (CNS) disorders involving elevated levels of cytokines.
    PDE4-IN-16
  • HY-W230975
    (E/Z)-Piperine 7780-20-3 98.91%
    (E/Z)-Piperine ((E/Z)-Bioperine) is an alkaloid with a pungent property. (E/Z)-Piperine shows anti-inflammation, immunomodulatory and anti-cancer, antispasmodic and anti-secretory effects. (E/Z)-Piperine demonstrates significant neuroprotective effect in Alzheimer’s disease and Parkinson’s disease.
    (E/Z)-Piperine
  • HY-W265961
    Squoxin 1096-84-0 98%
    Squoxin (ST1859) is an antiamyloid agent that specifically binds to Aβ1-42 and prevents the aggregation and fibril formation of Aβ. Squoxin crosses the blood-brain barrier (BBB) and has anthelmintic activity and anti-inflammatory properties.
    Squoxin
  • HY-W277900
    2-Methoxy-2,4-diphenylfuran-3-one 50632-57-0 98%
    2-Methoxy-2,4-diphenylfuran-3-one is a fluorescent compound which can be used to label gelatin as a substrate for detection of the gelatin degrading MMP-2 and MMP-9 by zymography.
    2-Methoxy-2,4-diphenylfuran-3-one
  • HY-W281862
    Sequifenadine 57734-69-7 98%
    Sequifenadine is a H1-antihistamine. Sequifenadine has the potential for the research of inflammatory eye disease with allergic symptoms.
    Sequifenadine
  • HY-W286423
    L-Pyroglutamic acid 7-amido-4-methylcoumarin 66642-36-2 98%
    L-Pyroglutamic acid 7-amido-4-methylcoumarin is a fluorogenic substrate for pyroglutamate aminopeptidase 1 (PGP-1).
    L-Pyroglutamic acid 7-amido-4-methylcoumarin
  • HY-W322573
    (R)-Ketoprofen 56105-81-8 98%
    (R)-Ketoprofen is an orally active nonsteroidal anti-inflammatory drug (NSAID) with analgesic properties. (R)-Ketoprofen does not significantly amplify the increase of inflammatory cytokines (such as tumor necrosis factor (TNF) and interleukin-1 (IL-1)) induced by LPS, but it can inhibit the anti-inflammatory activity of (S)-Ketoprofen.
    (R)-Ketoprofen
  • HY-W335927
    MAO-B-IN-19 152897-41-1 98%
    MAO-B-IN-19 is a selective MAO-B inhibitor with an IC50 of 0.67 μM. MAO-B-IN-19 shows neuroprotective and anti-inflammatory properties.
    MAO-B-IN-19
  • HY-W339645
    Naproxen ethyl ester 31220-35-6 98%
    Naproxen ethyl ester ((S)-Naproxen ethyl ester) is a nonsteroidal anti-inflammatory drug with activity in relieving pain, fever, swelling and stiffness. Naproxen ethyl ester exerts its effects by inhibiting non-selective cyclooxygenase (COX). The R-(-)-isomer of Naproxen ethyl ester shows stronger immunogenicity, and the Michaelis-Menten parameter of its catalytic reaction is K(M)=6.67 mM, and the catalytic efficiency is 5.8 x 10^4 times higher than that of the non-catalytic reaction.
    Naproxen ethyl ester
  • HY-W341962
    Halometasone 50629-82-8 98%
    Halometasone is a corticosteroid compound that can reduce the expression of serum leukotriene B4 (LTB4) and thymic stromal lymphopoietin (TSLP). Halometasone can be used in research on psoriasis and eczematous skin diseases.
    Halometasone
  • HY-W345148
    2-Naphthylamine-6,8-disulfonic acid potassium 842-15-9 98%
    2-Naphthylamine-6,8-disulfonic acid potassium is chemical that can be used for preparing dyestuff, medicine, agricultural chemicals etc.
    2-Naphthylamine-6,8-disulfonic acid potassium
  • HY-W357142
    3-Acetylumbelliferyl β-D-Glucopyranoside 20943-16-2 98%
    3-Acetylumbelliferyl β-D-Glucopyranoside is a fluorogenic substrate for β-glucosidase and can be used as a positive control substrates for β-D-glucosidase.
    3-Acetylumbelliferyl β-D-Glucopyranoside
  • HY-W371164
    C1s-IN-1 1016866-61-7 98%
    C1s-IN-1 (compound A1) is a selective and competitive inhibitor of C1s. C1s-IN-1 binds directly to C1s with a Kd of 9.8 μM.
    C1s-IN-1
  • HY-W403075
    N-(3-Methoxybenzyl)stearamide 1429659-99-3 98%
    N-(3-Methoxybenzyl)stearamide a natural product from Lepidium meyenii (Maca), inhibits human and mouse soluble epoxide hydrolase (hsEH and msEH) with IC50s of 0.001 and <0.001 μg/nM, respectively.
    N-(3-Methoxybenzyl)stearamide
  • HY-W424851
    DPQ hydrochloride 84050-22-6 98%
    DPQ hydrochloride is a blood-brain barrier permeable and selective PARP-1 inhibitor that blocks PARP-1-mediated DNA damage repair and NAD+/ATP consumption, thereby inhibiting excessive inflammatory responses. DPQ hydrochloride inhibits NF-κB pathway activation, reduces the expression of pro-inflammatory factors (such as TNF-α, IL-6) and oxidative stress. DPQ hydrochloride can be used in inflammation-related studies of acute lung injury, myocardial infarction, and neurodegenerative diseases.
    DPQ hydrochloride
Cat. No. Product Name / Synonyms Application Reactivity