2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

Related Products

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-P991341
    FF-21101 98%
    FF-21101 is a human IgG1 monoclonal antibody (mAb) targeting CDH3/P-cadherin. Recommend Isotype Controls: Human IgG1 kappa, Isotype Control (HY-P99001).
    FF-21101
  • HY-P991346
    CC-90006
    CC-90006 is a human monoclonal antibody (mAb) targeting PDCD1/PD-1/CD279. CC-90006 can be used in psoriasis research. Recommended isotype control: Human IgG1 kappa, Isotype Control (HY-P99001).
    CC-90006
  • HY-P991351
    RTX-002
    RTX-002 is a human monoclonal antibody (mAb) targeting PDCD1/PD-1/CD279. RTX-002 can be used to study autoimmune diseases such as systemic lupus erythematosus and multiple sclerosis.
    RTX-002
  • HY-P991363
    AX-202
    AX-202 is a human monoclonal antibody (mAb) targeting S100A4. AX-202 has antifibrotic effects in the mouse Tsk-1 model. AX-202 can be used in Plaque psoriasis and Systemic scleroderma research.
    AX-202
  • HY-P991399
    CNTO-3157
    CNTO-3157 is a human IgG4 monoclonal antibody (mAb) targeting TLR3/CD283. CNTO-3157 can be used in Asthma and Ulcerative colitis research.
    CNTO-3157
  • HY-P991400
    GSK1995057
    GSK1995057 is a human monoclonal antibody (mAb) targeting TNFRSF1A. GSK1995057 attenuates pulmonary neutrophilia, inflammatory cytokine release and signs of endothelial injury in bronchoalveolar lavage and serum samples. GSK1995057 can be used in Acute lung injury and Adult respiratory distress syndrome research. Recommended isotype control: dAb (VHH-His).
    GSK1995057
  • HY-P991401
    GSK2862277
    GSK2862277 is a human monoclonal antibody (mAb) targeting TNFRSF1A. GSK2862277 increases neutrophil extracellular trap formation and alveolar macrophage phagocytosis. GSK2862277 can be used in Acute lung injury and Acute Respiratory Distress Syndrome (ARDS) research. Recommended isotype control: VHH-hFc.
    GSK2862277
  • HY-P991407
    PF-05230905
    PF-05230905 is a human monoclonal antibody (mAb) targeting TNFSF2/TNFa. PF-05230905 can be used in Rheumatoid arthritis research.
    PF-05230905
  • HY-P991408
    DLX-105
    DLX-105 is a human monoclonal antibody (mAb) targeting TNFSF2/TNFa. DLX-105 reduces skin epidermal thickness and the expression of K16 and Ki67. DLX-105 down-regulates the mRNA levels of IL-17, TNF-α, IL-23p19, IL-12p40, and IFN-γ. DLX-105 can be used in psoriasis research.
    DLX-105
  • HY-P991409
    GSK2800528
    GSK2800528 is a human monoclonal antibody (mAb) targeting TNFSF2/TNFa. GSK2800528 can be used in inflammation and psoriasis research.
    GSK2800528
  • HY-P991424
    GSK2618960
    GSK2618960 is a human monoclonal antibody (mAb) targeting IL-7Ra/CD127. GSK2618960 inhibits IL-7-induced STAT5 phosphorylation. GSK2618960 enhances CD4 T cell proliferation response and increases CD83, CD86, and CD209 expression in PBMCs. GSK2618960 can be used in Multiple sclerosis and Sjogren's syndrome research. Recommended isotype control: Human IgG1 kappa, Isotype Control (HY-P99001).
    GSK2618960
  • HY-P991434
    SAN-300
    SAN-300 is a human IgG1 monoclonal antibody (mAb) targeting ITGA1/VLA-1. SAN-300 can be used in Rheumatoid arthritis research.
    SAN-300
  • HY-P991439
    BIIB023 98%
    BIIB023 is a human monoclonal antibody (mAb) targeting TNFRSF12A/TWEAKR/CD266. BIIB023 can be used in lupus nephritis and rheumatoid arthritis research.
    BIIB023
  • HY-P991440
    AMG-966 98%
    AMG-966 is a human bispecific antibody (bsAb) targeting TNFSF15/TL1A & TNFα. AMG 966 restores the ability of the aglycosylated Fc domain to bind to FcγRIa and FcγRIIa, leading to the formation of antidrug antibodies (ADA). AMG-966 can be used in Crohn's disease and Ulcerative colitis research. Recommended isotype control: Human IgG1 kappa, Isotype Control (HY-P99001).
    AMG-966
  • HY-P991467
    RG-7258
    RG-7258 is a human monoclonal antibody (mAb) targeting CRLF2. RG-7258 blocks dendritic cell activation and mast cell cytokine release. RG-7258 reduces Th2 inflammation in a non-human primate model of allergic lung inflammation. RG-7258 can be used in asthma research.
    RG-7258
  • HY-P991485
    Anti-CD88/C5AR1 Antibody (G2_anti-C5aR)
    Anti-CD88/C5AR1 Antibody (G2_anti-C5aR) is a human monoclonal antibody (mAb) targeting C5AR1.
    Anti-CD88/C5AR1 Antibody (G2_anti-C5aR)
  • HY-P991486
    Anti-DCBLD2CLCP1 Antibody (FA19-1)
    Anti-DCBLD2CLCP1 Antibody (FA19-1) is a human monoclonal antibody (mAb) targeting DCBLD2.
    Anti-DCBLD2CLCP1 Antibody (FA19-1)
  • HY-P991487
    LASN01 98%
    LASN01 is a human IgG1 monoclonal antibody (mAb) targeting IL-11RA. LASN01 inhibits IGF-1 and IL-11-induced hyaluronic acid (HA) release and TGFβ-stimulated procollagen in orbital fibroblasts. LASN01 can be used in thyroid eye disease (TED) research. Recommended isotype control: Human IgG1 kappa, Isotype Control (HY-P99001).
    LASN01
  • HY-P991488
    BI-765423 98%
    BI-765423 is a human monoclonal antibody (mAb) targeting IL-11. BI-765423 can be used in fibrotic diseases research.
    BI-765423
  • HY-P991489
    ENx-108A 98%
    ENx-108A is a human IgG4 monoclonal antibody (mAb) targeting IL-11. BI-765423 can be used in fibrotic diseases research. Recommended isotype control: Human IgG4 kappa, Isotype Control (HY-P99003).
    ENx-108A
Cat. No. Product Name / Synonyms Application Reactivity