2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

Related Products

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-B0227R
    Ketoprofen (Standard) 22071-15-4
    Ketoprofen (Standard) is the analytical standard of Ketoprofen. This product is intended for research and analytical applications. Ketoprofen (RP-19583) is a non-steroidal anti-inflammatory agent. Ketoprofen can inhibits the activity of cyclooxygenase with IC50 values of 2 nM (COX-1) and 26 nM (COX-2). which is potential in the research of inflammation, immunology, and metabolic disease such as obesity.
    Ketoprofen (Standard)
  • HY-B0230A
    Thiazolinobutazone 54749-86-9 98%
    Thiazolinobutazone is a COX inhibitor. Thiazolinobutazone has less toxic than Phenylbutazone (HY-B0230). Thiazolinobutazone can be used in the study of immunological diseases.
    Thiazolinobutazone
  • HY-B0230B
    Pyrazinobutazone 4985-25-5 98%
    Pyrazinobutazone (Phenylbutazone piperazium) is an antipyrene derivative that possesses anti-inflammatory properties and has been associated with hypersensitivity reactions leading to agranulocytosis and liver injury.
    Pyrazinobutazone
  • HY-B0260S
    Methylprednisolone-d3 98%
    Methylprednisolone-d3 is the deuterium labeled Methylprednisolone. Methylprednisolone is a synthetic corticosteroid with anti-inflammatory and immunomodulating properties. Methylprednisolone improve severe or critical COVID-19 by activating ACE2 and reducing IL-6 levels.
    Methylprednisolone-d3
  • HY-B0261A
    Meloxicam sodium 71125-39-8 98%
    Meloxicam sodium is a non-steroidal anti-inflammatory agent, inhibits COX activity, with IC50s of 0.49 µM and 36.6 µM for COX-2 and COX-1, respectively.
    Meloxicam sodium
  • HY-B0264S
    Guaifenesin-d3 1189924-85-3 99.00%
    Guaifenesin-d3 is the deuterium labeled Guaifenesin. Guaifenesin (Guaiacol glyceryl ether), a constituent of guaiac resin from the wood of Guajacum officinale Linné, is an expectorant. Guaifenesin can alleviate cough discomfortby increasing sputum volume and decreasing its viscosity, thereby promoting effective cough.
    Guaifenesin-d3
  • HY-B0286R
    Chlorpheniramine (Standard) 132-22-9
    Chlorpheniramine (Standard) is the analytical standard of Chlorpheniramine. This product is intended for research and analytical applications. Chlorpheniramine is a H1 antihistamines commonly used in allergic diseases research.
    Chlorpheniramine (Standard)
  • HY-B0289S
    Erdosteine-13C4 98%
    Erdosteine-13C4 is a 13C-labeled Erdosteine. Erdosteine inhibits lipopolysaccharide (LPS)-induced NF-κB activation. Erdosteine has muco-modulatory, anti-bacterial, anti-inflammatory and anti-oxidant effects.
    Erdosteine-13C4
  • HY-B0300S
    Penicillamine-d3 2925655-01-0 98%
    Penicillamine-d3 is the deuterium labeled Penicillamine. Penicillamine (D-(-)-Penicillamine) is the most characteristic degradation product of the penicillin antibiotics. It is used as an antirheumatic and as a chelating agent in Wilson's disease.
    Penicillamine-d3
  • HY-B0335R
    Tolfenamic Acid (Standard) 13710-19-5 99.97%
    Tolfenamic Acid (Standard) is the analytical standard of Tolfenamic Acid. This product is intended for research and analytical applications. Tolfenamic Acid (GEA 6414) is a non-steroidal anti-inflammatory and anti-cancer agent, selectively inhibits COX-2, with an IC50 of 13.49 μM (3.53 μg/mL) in LPS-treated (COX-2) canine DH82 monocyte/macrophage cells, but shows no effect on COX-1.
    Tolfenamic Acid (Standard)
  • HY-B0335S
    Tolfenamic acid-d4 1246820-82-5 98%
    Tolfenamic acid-d4 is the deuterium labeled Tolfenamic Acid. Tolfenamic Acid (GEA 6414) is a non-steroidal anti-inflammatory and anti-cancer agent, selectively inhibits COX-2, with an IC50 of 13.49 μM (3.53 μg/mL) in LPS-treated (COX-2) canine DH82 monocyte/macrophage cells, but shows no effect on COX-1.
    Tolfenamic acid-d4
  • HY-B0349S
    Meclizine-d8 1246816-06-7 98%
    Meclizine-d8 is a deuterium labeled Meclizine. Meclizine is a histamine H1 receptor antagonist and has the potential to treat nausea and motion sickness. Meclizine is an agonist ligand for mouse constitutive androstane receptor (CAR) and an inverse agonist for Human CAR.
    Meclizine-d8
  • HY-B0377G
    Famotidine (GMP) 76824-35-6 98%
    Famotidine GMP (MK-208 GMP) is Famotidine (HY-B0377) produced in GMP guideline. Famotidine GMP is a competitive histamine H2-receptor antagonist, inhibits gastric secretion, activates the gastric mucosal defensive mechanisms. Famotidine GMP ameliorates peptic ulcer disease (PUD) and gastroesophageal reflux disease (GERD/GORD) in rats model.
    Famotidine (GMP)
  • HY-B0428D
    (E/Z)-Ozagrel sodium 130952-46-4 98%
    (E/Z)-Ozagrel sodium [(E/Z)-OKY-046 sodium] is an EZ configuration mixture of Ozagrel sodium (HY-B0428A). Ozagrel sodium (OKY-046 sodium) is a high selective and orally active thromboxane A2 (TXA2) synthase inhibitor with an IC50 of 11 nM. Ozagrel sodium exerts anti-platelet aggregation, vasodilation and anti-inflammatory effects by inhibiting the production of TXA2 and increasing the production of prostacyclin (PGI2). Ozagrel sodium can be used for the study of ischemic stroke, asthma and thromboembolic diseases.
    (E/Z)-Ozagrel sodium
  • HY-B0440S
    Tenoxicam-d3 98%
    Tenoxicam-d3 is the deuterium labeled Tenoxicam. Tenoxicam (Ro-12-0068), an antiinflammatory agent with analgesic and antipyretic properties.
    Tenoxicam-d3
  • HY-B0450R
    Ciclopirox (Standard) 29342-05-0
    Ciclopirox (Standard) is the analytical standard of Ciclopirox. This product is intended for research and analytical applications. Ciclopirox (HOE296b) is a synthetic and orally active antifungal agent that can be used for superficial mycoses reseaech. Ciclopirox olamine has a very broad spectrum of activity and inhibits dermatophytes, yeasts, molds, and many Gram-positive and Gram-negative species pathogenic. Ciclopirox also has anticancer and anti-inflammatory effect.
    Ciclopirox (Standard)
  • HY-B0462B
    (S)-Azelastine hydrochloride 153408-27-6 98%
    (S)-Azelastine hydrochloride, an antihistamine, is a potent and selective histamine 1 (H1) antagonist. (S)-Azelastine hydrochloride can be used for the research of allergic rhinitis, asthma, diabetic hyperlipidemic and SARS-CoV-2.
    (S)-Azelastine hydrochloride
  • HY-B0462C
    (R)-Azelastine hydrochloride 153408-28-7 98%
    (R)-Azelastine hydrochloride, an antihistamine, has been demonstrated to down-regulate the levels of H1R, M1R, and M3R, while also inhibiting the proliferation of HNEpC.
    (R)-Azelastine hydrochloride
  • HY-B0462S
    Azelastine-13C,d3 hydrochloride 98%
    Azelastine-13C,d3 (hydrochloride) is the 13C- and deuterium labeled Azelastine hydrochloride. Azelastine-13C,d3 (hydrochloride), an antihistamine, is a potent and selective histamine 1 (H1) antagonist. Azelastine-13C,d3 (hydrochloride) can be used for the research of allergic rhinitis, asthma, diabetic hyperlipidemic and SARS-CoV-2.
    Azelastine-13C,d3 hydrochloride
  • HY-B0466R
    Cloxacillin sodium monohydrate (Standard) 7081-44-9
    Cloxacillin (sodium monohydrate) (Standard) is the analytical standard of Cloxacillin (sodium monohydrate). This product is intended for research and analytical applications. Cloxacillin sodium monohydrate is an orally active antibacterial agent and β-lactamase inhibitor with an IC50 of 0.04 μM. Cloxacillin sodium monohydrate can suppress the S. aureus-induced inflammatory response by inhibiting the activation of MAPKs, NF-кB and NLRP3-related proteins.
    Cloxacillin sodium monohydrate (Standard)
Cat. No. Product Name / Synonyms Application Reactivity