2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-177576
    CCR5 modulator-1 960296-78-0
    CCR5 modulator-1 (Compound 26) is a CCR5 modulator. CCR5 modulator-1 can be used for the study of inflammation.
    CCR5 modulator-1
  • HY-177611
    Agazisiran 2985646-78-2 98%
    Agazisiran, a siRNA,is a complement factor B synthesis reducer.
    Agazisiran
  • HY-177621
    Cevolisiran 3069641-77-3 98%
    Cevolisiran, a siRNA, is a complement component 3 (C3) synthesis reducer.
    Cevolisiran
  • HY-177623
    CpG-ODN c41 1228853-94-8
    CpG-ODN c41, an oligonucleotide, is an antagonist of TLR9.
    CpG-ODN c41
  • HY-177624
    Cupabimod 297774-48-2
    Cupabimod is a decoy oligodeoxynucleotide for transcription factor NF-κB.
    Cupabimod
  • HY-177627
    Edifoligide 328538-04-1
    Edifoligide is a decoy oligonucleotide that binds to and inhibits E2F transcription factors and thus may prevent neointimal hyperplasia and vein graft failure
    Edifoligide
  • HY-177652
    Onvuzosiran 2982817-49-0 98%
    Onvuzosiran, a siRNA, is a prekallikrein synthesis reducer.
    Onvuzosiran
  • HY-177691
    CCI17464 325780-75-4 98%
    CCI17464 is a selective, orally active EP4 agonist. CCI17464 can be used in a Freund's complete adjuvant (FCA) acute rat inflammatory pain model and shows complete reversal of allergic reactions.
    CCI17464
  • HY-177700
    Immunosuppressant-2 854108-48-8 98%
    Immunosuppressant-2 is an orally active immunosuppressant. Immunosuppressant-2 significantly reduces the number of circulating lymphocytes. Immunosuppressant-2 can be used for research on various autoimmune diseases and organ transplant rejection.
    Immunosuppressant-2
  • HY-177712
    RORγt inverse agonist 36 1599530-54-7
    RORγt inverse agonist 36 (S configuration of Compound 16) is a RORγt inverse agonist. RORγt inverse agonist 36 can be used for the research of inflammation and immunology.
    RORγt inverse agonist 36
  • HY-177726
    UTPU trisodium 401618-61-9
    UTPU (trisodium) (Compound 19) is a selective P2Y6R agonist with an EC50 of 0.4 μM. UTPU (trisodium) can activate the intracellular calcium signaling pathway mediated by P2Y6. UTPU (trisodium) can be used for the research of inflammation.
    UTPU trisodium
  • HY-177754
    IKZF2-degrader 3 2983841-46-7
    IKZF2-degrader 3 (compound 6) is a molecular glue IKZF2 degrader with a DC50 of 2.0 nM.
    IKZF2-degrader 3
  • HY-177800
    ARC5690 sodium
    ARC5690 sodium is an anti-mouse P-selectin aptamer. ARC5690 bound to recombinant mouse P-selectin with a KD of approximately 15pM in vitro. ARC5690 showed a significant anti-inflammatory effect
    ARC5690 sodium
  • HY-177803
    Protein C aptamer sodium
    Protein C aptamer sodium is a 44mer-DNA aptamer that the anticoagulant functions of activated protein C. Activated protein C (APC) is a serine protease with anticoagulant, anti-inflammatory, and cytoprotective properties.
    Protein C aptamer sodium
  • HY-177804
    Thrombin aptamer sodium
    Thrombin aptamer is a 11mer-DNA aptamer that targets thrombin. Thrombin aptamer inhibites thrombin-catalysed fibrin-clot formation in vitro
    Thrombin aptamer sodium
  • HY-177809
    aptTNF-α sodium
    aptTNF-α sodium is a TNF-α-targeting aptamer that has tissue protective effect and systemic anti-inflammatory effect upon acute tissue injury using the mouse acute lung injury (ALI) and acute liver failure (ALF) models.
    aptTNF-α sodium
  • HY-177819
    DTA-64 sodium 98%
    DTA-64 sodium is a aptamer targeted DEK. It significantly reduces joint inflammation in zymosan-induced arthritis mouse model and greatly impairs the ability of neutrophils to form neutrophil extracellular traps (NETs). DEK is a secreted protein abundant
    DTA-64 sodium
  • HY-177834
    Liposomal zinc
    Liposomal zinc is a specialized delivery system that encapsulates zinc compound within tiny liposomes. These liposomes act as protective shells, enhancing the absorption and bioavailability of zinc. Zinc is an important trace element and plays a key role
    Liposomal zinc
  • HY-177839
    Liposomal coenzyme Q10
    Liposomal coenzyme Q10 is a specialized delivery system that encapsulates coenzyme Q10 within tiny liposomes. These liposomes act as protective shells, enhancing the absorption and bioavailability of coenzyme Q10. Coenzyme Q10 (CoQ10), also called ubiquin
    Liposomal coenzyme Q10
  • HY-177840
    Liposomal curcumin
    Liposomal curcumin is a specialized delivery system that encapsulates curcumin within tiny liposomes. These liposomes act as protective shells, enhancing the absorption and bioavailability of curcumin. Curcumin is a polyphenol compound extracted from the
    Liposomal curcumin
Cat. No. Product Name / Synonyms Application Reactivity