2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

Related Products

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-120039A
    (S)-MDL-101146 163660-59-1 98%
    (S)-MDL-101146 is the S-isomer of MDL-101146. MDL-101146 is an orally active, competitive and reversible inhibitor against human neutrophil elastase (HNE) with a Ki value of 25 nM. MDL-101146 inhibits HNE-induced hemorrhage in hamsters. MDL-101146 is promising for research of emphysema, rheumatoid arthritis, chronic bronchitis, cystic fibrosis, adult respiratory distress syndrome and glomerulonephritis.
    (S)-MDL-101146
  • HY-120541A
    ST-1006 Maleate 1196994-12-3 98%
    ST-1006 maleate is a potent histamine H4 receptor agonist with a pKi value of 7.94. ST-1006 maleate has anti-inflammatory effect.
    ST-1006 Maleate
  • HY-120611A
    BMS-960 1265323-40-7 98%
    BMS-960 is a potent and selective S1P1 receptor agonist containing isoxazole, which can be used in the research of immune diseases and vascular diseases.
    BMS-960
  • HY-120657R
    9-PAHSA (Standard) 1481636-31-0
    Flumethrin (Standard) is the analytical standard of Flumethrin. This product is intended for research and analytical applications. Flumethrin is an active compound.
    9-PAHSA (Standard)
  • HY-120785A
    SR1555 hydrochloride 2309312-90-9 98%
    SR1555 hydrochloride is the hydrochloride salt form of SR1555 (HY-120785). SR1555 hydrochloride is an inverse agonist for retinoic acid receptor-related orphan nuclear receptor γ (RORγ) with an IC50 of 1 μM. SR1555 hydrochloride inhibits the development and function of pro-inflammatory TH17 cell, increases the frequency of anti-inflammatory T regulatory (Treg) cells. SR1555 hydrochloride can be used for research about autoimmune diseases.
    SR1555 hydrochloride
  • HY-120802A
    Navafenterol saccharinate 1648550-37-1 98%
    Navafenterol (AZD-8871) saccharinate is an inhaled dual-acting, potent, selective, and long-lasting M3-antagonist/β2-agonist (MABA) with long-lasting effects and favorable safety profile. The pIC50 is 9.5 for human M3 receptor, and the pEC50 is 9.5 for β2-adrenoceptor. Navafenterol saccharinate can be used for the research of chronic obstructive pulmonary disease (COPD). Bronchoprotective and antisialagogue effects. Favorable cardiovascular profile.
    Navafenterol saccharinate
  • HY-120813A
    ARN 077 (enantiomer) 1439366-88-7 99.71%
    ARN 077 enantiomer (19) is the less active enantiomer of ARN 077, with an IC50 of 3.53 μM for rat NAAA.
    ARN 077 (enantiomer)
  • HY-12085S2
    (Rac)-Apremilast-d5 1258597-61-3 98%
    (Rac)-Apremilast-d5 is a deuterium labeled (R)-Apremilast. (R)-Apremilast ((R)-CC-10004) is a enantiomer of Apremilast.
    (Rac)-Apremilast-d5
  • HY-12085S3
    Apremilast-d3 1258597-46-4 98%
    Apremilast-d3 (CC-10004-d3) is deuterium labeled Apremilast. Apremilast (CC-10004) is an orally available inhibitor of type-4 cyclic nucleotide phosphodiesterase (PDE-4) with an IC50 of 74 nM. Apremilast inhibits TNF-α release by lipopolysaccharide (LPS) with an IC50 of 104 nM.
    Apremilast-d3
  • HY-120994A
    Rp-8-CPT-cAMPS 129735-01-9 98%
    Rp-8-CPT-cAMPS, a cAMP analog, is a potent and competitive antagonist of cAMP-induced activation of cAMP-dependent PKA I and II. Rp-8-CPT-cAMPS preferentially selects site A of RI compares to site A of RII and site B of RII compares to site B of RI.
    Rp-8-CPT-cAMPS
  • HY-120994B
    Sp-8-CPT-cAMPS 129693-13-6 98%
    Sp-8-CPT-cAMPS, a cAMP analog, is a potent and selective activator of the cAMP-dependent protein kinas A (PKA I and PKA II). Sp-8-CPT-cAMPS selects site A of RI compares to site A of RII by 153-fold and site B of RII compares to site B of RI by 59-fold.
    Sp-8-CPT-cAMPS
  • HY-12100S1
    Umeclidinium-d10 bromide 98%
    Umeclidinium-d10 (bromide) is the deuterium labeled Umeclidinium bromide. Umeclidinium bromide is a novel mAChR antagonist. The affinity (Ki) of Umeclidinium bromide for the cloned human M1-M5 mAChRs ranges from 0.05 to 0.16 nM.
    Umeclidinium-d10 bromide
  • HY-121043A
    AA 497 65860-38-0 98%
    AA 497 is an adrenergic beta-2 agonist. AA 497 is a bronchodilator.
    AA 497
  • HY-121212R
    Icosabutate (Standard) 1253909-57-7
    Desmethyl Sibutramine (hydrochloride) (Standard) is the analytical standard of Desmethyl Sibutramine (hydrochloride). This product is intended for research and analytical applications. Desmethyl Sibutramine hydrochloride, the secondary metabolite of Sibutramine, is an orally active norepinephrine transporter (NET) and serotonin transporter (SERT) inhibitor. Desmethyl Sibutramine hydrochloride can be used in the research of obesity and appetite suppressant.
    Icosabutate (Standard)
  • HY-121268A
    Demeclocycline calcium 17146-81-5 98%
    Demeclocycline (calcium) is an orally active tetracycline antibiotic that inhibits the binding of aminoacyl tRNA by binding to the 30S ribosomal subunit, thereby affecting protein synthesis. Demeclocycline (calcium) exhibits antibacterial activity against a broad spectrum of bacterial infections.
    Demeclocycline calcium
  • HY-121362R
    Evernic Acid (Standard) 537-09-7
    Propazine (Standard) is the analytical standard of Propazine. This product is intended for research and analytical applications. Propazine is a triazine herbicide that effectively manages broad-leaved weeds and annual grasses in sweet sorghum cultivation.
    Evernic Acid (Standard)
  • HY-121467A
    Acotiamide hydrochloride 185104-11-4 99.62%
    Acotiamide hydrochloride is an orally active, selective and reversible acetylcholinesterase (AChE) inhibitor, with an IC50 of 1.79 μM. Acotiamide hydrochloride can enhance gastric contractility and accelerate delayed gastric emptying. Acotiamide hydrochloride has the potential for the research of functional dyspepsia involving gastric motility dysfunction and intestinal inflammatory.
    Acotiamide hydrochloride
  • HY-121854A
    Bromadoline maleate 81447-81-6 98%
    Bromadoline maleate is an opioid analgesic selective for the μ-opioid receptor, exhibiting analgesic activity in various biological fluids. Bromadoline maleate has been successfully quantified alongside its N-demethylated metabolites in human and canine samples.
    Bromadoline maleate
  • HY-121936R
    Yohimbic acid (Standard) 522-87-2
    Hexyl methanesulfonate (Standard) is the analytical standard of Hexyl methanesulfonate. This product is intended for research and analytical applications. Hexyl methanesulfonate (Methanesulfonic acid hexyl ester) is an ester product.
    Yohimbic acid (Standard)
  • HY-122267A
    cis-Clovamide 53755-03-6 98%
    cis-Clovamide, a natural phenolic compound with antioxidant, anti-inflammatory and antiapoptotic activities.
    cis-Clovamide
Cat. No. Product Name / Synonyms Application Reactivity