2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

Related Products

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-12866B
    (R)-Larotrectinib 1223404-68-9 98%
    (R)-Larotrectinib is a potent TRK inhibitor with an IC50 value of 28.5 nM for TrkA. (R)-Larotrectinib can be used for researching cancer, inflammatory and certain infectious diseases
    (R)-Larotrectinib
  • HY-128695
    Oleanolic acid hemiphthalate disodium salt 168770-31-8 98.05%
    Oleanolic acid hemiphthalate disodium salt is a hemiphthalate derivative of Oleanolic acid (HY-128695) with anti-inflammatory and potential anti-ulcer activities.
    Oleanolic acid hemiphthalate disodium salt
  • HY-128934
    Antitumor agent-2 1351163-57-9 98%
    Antitumor agent-2 is sourced from patent CN102250203, compound 6a-r, has antitumor action and anti-inflammatory action.
    Antitumor agent-2
  • HY-129214
    (2S,3R)-DEPMPO-Biotin 936224-52-1 98%
    (2S,3R)-DEPMPO-Biotin is a spin trapping agent consists of DEPMPO (HY-120976) and Biotin (HY-B0511). (2S,3R)-DEPMPO-Biotin captures macromolecule free radicals in lesions.
    (2S,3R)-DEPMPO-Biotin
  • HY-129311
    Tr-PEG6-OH 127999-16-0
    Tr-PEG6-OH is a non-cleavable 6 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
    Tr-PEG6-OH
  • HY-129424
    Mezolidon 82697-73-2 98%
    Mezolidon (KM-1146) is a compound with anti-ulcer activity, which exerts its anti-ulcer activity by enhancing the defense ability of gastric mucosa, especially by increasing and maintaining gastric mucosal blood flow and protecting gastric mucosal potential difference. Mezolidon can be used for the study of gastric mucosal protection.
    Mezolidon
  • HY-129466
    PCTR2 1810710-63-4 98%
    PCTR2 is a protectin sulfidoconjugate, which is a pro-resolving mediator that exhibits activity towards inflammation and tissue regeneration.
    PCTR2
  • HY-12946A
    BI 653048 phosphate 1198784-97-2 98%
    BI 653048 phosphate is a selective and orally active nonsteroidal glucocorticoid (GC) agonist with an IC50 value of 55 nM. BI 653048 phosphate inhibits CP1A2, CYP2D6, CYP2C9, CYP2C19 and CYP3A4 isoforms’ activity and reduces affinity for the hERG ion channel (IC50>30 μM). BI 653048 phosphate is extracted from patent WO2005028501A1 (Compound 103), is also a HCV NS3 protease inhibitor that can reduce viral loads infected with the hepatitis C virus.
    BI 653048 phosphate
  • HY-129471
    Arbaprostil 55028-70-1 98%
    Arbaprostil is an orally active PGE1 (HY-B0131) analog. Arbaprostil protects the gastrointestinal mucosa from stomach acid and other irritants, promotes healing rate of gastric ucler through the antisecretory effect.
    Arbaprostil
  • HY-129546
    Eprozinol hydrochloride 27588-43-8 98%
    Eprozinol hydrochloride is a compound with antibronchoconstrictor activity. Eprozinol hydrochloride can be used in the study of bronchospasm.
    Eprozinol hydrochloride
  • HY-129664
    L 683519 132172-14-6 98%
    L 683519, one of the impurities of tacrolimus, is an immunosuppressant. L 683519 can inhibit the activity of FK-506 binding protein.
    L 683519
  • HY-129670
    KMUP-1 81996-46-5
    KMUP-1 is a xanthine derivative with vasodilator activity. KMUP-1 is a inhibitor of phosphodiesterase (PDE) and activator of soluble guanylyl cyclase (sGC). KMUP-1 stimulates NO/sGC/cyclic GMP pathway. KMUP-1 has K+ channels opening activity. KMUP-1 ameliorates ischemia-induced cardiomyocyte apoptosis. KMUP-1 can be used for cardiovascular and anti-inflammatory study.
    KMUP-1
  • HY-129684
    IAXO-101 iodide 1202388-64-4 98%
    IAXO-101 (iodide) is a TLR4/CD14 blocker. IAXO-101 (iodide) can inhibit the innate immune pathway of CD14. IAXO-101 (iodide) is capable of improving the recording performance of intracortical microelectrodes in mice. IAXO-101 (iodide) can also partially alleviate fetal growth restriction, placental vascular damage, and reduce the level of the inflammatory factor TNF-α in pregnant mice infected with malaria. IAXO-101 (iodide) can be used in the research of gestational malaria and inflammatory diseases.
    IAXO-101 iodide
  • HY-129690
    UK-356202 223671-94-1 98%
    UK-356202 is a urokinase-type plasminogen activator (uPA) with a Ki value of 0.037 μM. UK-356202 can be used in research related to the topical treatment of chronic ulcerous wounds.
    UK-356202
  • HY-129716
    L-693989 138661-20-8 98%
    L-693989 is an orally active water-soluble lipopeptide with anticandidal and antipneumocystis activity. L-693989 is effective in preventing the development of both P. carinii cysts. L-693989 is promising for research of P. carinii pneumonia.
    L-693989
  • HY-129749
    IDO-IN-13 2291164-02-6 98%
    IDO-IN-13 is a potent indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor with an EC50 of 17 nM, extracted from patent WO2019040102A1, example 43.
    IDO-IN-13
  • HY-129764
    Prostaglandin F3α 745-64-2 98%
    Prostaglandin F3α (PGF3α) is an eicosapentaenoic acid (EPA)-derived bioactive lipid mediator that has anti-cancer and anti-inflammatory effects. Prostaglandin F3α is a substrate of ABCC4 with a Km of 12.1 μM. Prostaglandin F3α can be used for the research of diabetes.
    Prostaglandin F3α
  • HY-129944
    MJ33-OH 199106-13-3 98%
    MJ33-OH is a metabolite of MJ33. MJ33 is an active-site-directed, specific, competitive, and reversible phospholipase A2 (PLA2) inhibitor. MJ33 blocks the calcium-independent phospholipase A2 (iPLA2) activity of Prdx6.
    MJ33-OH
  • HY-129953
    9α,11β-Prostaglandin F2α 38432-87-0 98%
    9α,11β-Prostaglandin F2α is an endogenous metabolite present in Urine that can be used for the research of Asthma.
    9α,11β-Prostaglandin F2α
  • HY-129991
    JNJ-17166864 874887-03-3 98%
    JNJ-17166864 is a highly selective CCR2 antagonist. JNJ-17166864 has low oral bioavailability. JNJ-17166864 can significantly reduce the area of alveolar bone loss in a mouse model of periodontitis induced by Porphyromonas gingivalis infection. JNJ-17166864 can be used in the research of inflammatory diseases such as allergic rhinitis and periodontitis.
    JNJ-17166864
Cat. No. Product Name / Synonyms Application Reactivity