2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

Related Products

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-157198
    Dinotefuran-NHCO-propionic acid 98%
    Dinotefuran-NHCO-propionic acid (4) is an antigen. Dinotefuran-NHCO-propionic acid can couple BSA and OVA to obtain the immunogen and the coating antigen (hapten-OVA conjugate) .
    Dinotefuran-NHCO-propionic acid
  • HY-157200
    2,4-DA-6-FP 4261-17-0 98%
    2,4-DA-6-FP is a hapten and MR1 ligand. 2,4-DA-6-FP can used in study autoimmune diseases and cancers.
    2,4-DA-6-FP
  • HY-157202
    Zeoh 98%
    Zeoh, an immunizing and heterologous hapten, contains one unprotected OH group at a distal position.
    Zeoh
  • HY-157205
    Zeph 98%
    Zeph is a small chemical group double heterologous hapten of Zep and combines with a specific antibody but lacks antigenicity of its own.
    Zeph
  • HY-157211
    Anti-inflammatory agent 66 98%
    Anti-inflammatory agent 66 (compound 8) is a pterostilbene derivative with anti-inflammatory activity. Anti-inflammatory agent 66 inhibits pro-inflammatory cytokines by blocking the LPS-induced NF-κB/MAPK signaling pathway and effectively alleviates DSS-induced acute colitis in mice.
    Anti-inflammatory agent 66
  • HY-157223
    ARN16186 2320555-85-7 98%
    ARN16186;ARN 16186;ARN-16186
    ARN16186
  • HY-157258
    Trimethoprim pentanoic acid 78025-89-5 98%
    Trimethoprim pentanoic acid is hapten. Trimethoprim pentanoic acid shows IC50 of 0.15 ng/mL when exposed diaminopyrimidine moiety to the immune system.
    Trimethoprim pentanoic acid
  • HY-157269
    J10-1 1069110-72-0 98%
    J10-1 is a hapten. J10-1 promotes peptide exchange of all DR alleles (DR1, DR2, DR4 (DRB1*0401)) and promotes peptide binding to MHC II, which can be used in the study of immune regulation.
    J10-1
  • HY-157287
    (S)-Phe-A110/B319 98%
    (S)-Phe-A110/B319 is a selective binde that has 20-fold higher affinity towards the H1047R mutant of p110α in the p110α/p85α PI3K complex.
    (S)-Phe-A110/B319
  • HY-157348
    Lauryl Sulfate Tryptose Broth 98%
    Lauryl Sulfate Tryptose Broth can be used for preparation of selective enrichment broth.
    Lauryl Sulfate Tryptose Broth
  • HY-157375
    Brain Heart Infusion Agar 98%
    Brain Heart Infusion Agar is growth medium for the cultivation of a wide variety of microorganisms.
    Brain Heart Infusion Agar
  • HY-157394
    eeAChE/eqBuChE-IN-1 2921654-26-2 98%
    eeAChE/eqBuChE-IN-1 (compound 3F) is a reversible dual eeAChE/eqBuChE inhibitor with IC50s of 1.3?μM and 0.81?μM, respectively. eeAChE/eqBuChE-IN-1 exhibits anti-inflammatory activity. eeAChE/eqBuChE-IN-1 also shows neuroprotective effect on Aβ25-35-induced PC12 cell injury.
    eeAChE/eqBuChE-IN-1
  • HY-157437
    AChE/BChE-IN-16 98%
    AChE/BChE-IN-16 (compound C7) is a potent cholinesterase (ChE) inhibitor with IC50s of 30 nM and 48 nM for human acetylcholinesterase (hAChE) and human butyrylcholinesterase (hBChE), respectively. AChE/BChE-IN-16 exhibits a remarkable capacity to safeguard PC12 cells against H2O2-induced apoptosis and effectively suppresses the production of reactive oxygen species (ROS).
    AChE/BChE-IN-16
  • HY-157461
    Glycation-IN-1 3023711-86-3 98%
    Glycation-IN-1 (Compound 3) is an inhibitor of glycosylation reactions, which has a strong inhibitory effect on the synthesis of initial, intermediate, and final products of glycosylation reactions. Glycion-IN-1 can be used in the research of various chronic diseases, such as diabetes, immune inflammation, cardiovascular diseases and neurodegenerative diseases.
    Glycation-IN-1
  • HY-157546
    VEGFR-2-IN-40 98%
    VEGFR-2-IN-40 is a VEGFR-2 inhibitor. VEGFR-2-IN-40 boosts early and late apoptosis. VEGFR-2-IN-40 decreases the levels immunomodulatory proteins TNF-α and IL-6 while showing a four-fold rise in an apoptotic marker caspase-3.
    VEGFR-2-IN-40
  • HY-157554
    ZM640 98%
    ZM640 is a NLRP3 inhibitor. ZM640 enhances IL-1β release mediated by NLRP3 inflammasome activation in THP-1 cells. ZM640 shows low cytotoxicity.
    ZM640
  • HY-157751
    RIPK1-IN-21 3016304-64-3 98%
    RIPK1-IN-21 (Compound I-5) is an inhibitor of RIPK1 with an EC50 value of 14.8 nM. RIPK1-IN-21 can be used in the research of neurodegenerative, autoimmune, and inflammatory diseases.
    RIPK1-IN-21
  • HY-157766
    FAAH/TRPV1 blocker-1 98%
    FAAH/TRPV1 blocker-1 (compound 2R) is a dual FAAH/TRPV1 blocker, with IC50 of 0.12 and 94.9 μM, respectively. FAAH/TRPV1 blocker-1 plays an important role in analgesic and anti-inflammatory research.
    FAAH/TRPV1 blocker-1
  • HY-157807
    Prostaglandin E2-biotin 2641624-60-2 ≥99.0%
    Prostaglandin E2-biotin is a prostaglandin analog. Prostaglandin E2-biotin can be used for research of Nurr1-related disease, such as cancer and autoimmune disease.
    Prostaglandin E2-biotin
  • HY-157809
    Anti-inflammatory agent 74 98%
    Anti-inflammatory agent 74 (B5) is an anti-inflammatory agent that can inhibit NO, IL-6, and TNF-α, with IC50 values of 10.88 μM and 4.93 μM for NO and IL-6, respectively. Anti-inflammatory agent 74 alleviates acute lung injury (ALI) by regulating inflammatory mediators and inhibiting the MAPK and NF-κB signaling pathways.
    Anti-inflammatory agent 74
Cat. No. Product Name / Synonyms Application Reactivity