2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

Related Products

PDF 93.1 MB

The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-126127
    BRL 22321 free base 72364-91-1 98%
    BRL 22321 free base is a stabilizer with similar mast cell stabilizing activity to Cromolyn sodium (HY-B0320A) and also has some smooth muscle relaxant activity. BRL 22321 free base is more potent than Cromolyn sodium (HY-B0320A) in inhibiting rat passive cutaneous and peritoneal anaphylaxis and antigen-induced histamine release from passively sensitized rat peritoneal cells.
    BRL 22321 free base
  • HY-126157
    Linearol 37720-82-4 98%
    Linearol, a diterpene extracted from Sideritis L. spp. (Lamiaceae), exhibits a diverse array of properties, including potent antioxidant, anti-inflammatory, and anti-apoptotic effects.
    Linearol
  • HY-126232
    Verproside 50932-20-2 98%
    Verproside, a catalpol derivative iridoid glycoside isolated from the genus Pseudolysimachion, represses TNF-α -induced MUC5AC expression by inhibiting NF-κB activation via the IKK/IκB signaling cascade. Verproside has potent anti-inflammatory, antioxidant, antinociceptive and anti-asthmatic activities. Verproside has the potential for the study of chronic obstructive pulmonary disease (COPD).
    Verproside
  • HY-126390
    (E/Z)-BCI 15982-84-0 98%
    (E/Z)-BCI (NSC 150117) is a dual-specificity phosphatase 6 (DUSP6) inhibitor with anti-inflammatory activities. (E/Z)-BCI attenuates LPS-induced inflammatory mediators and ROS production in macrophage cells via activating the Nrf2 signaling axis and inhibiting the NF-κB pathway.
    (E/Z)-BCI
  • HY-126414
    Methylenedihydrotanshinquinone 126979-81-5 98%
    Methylenedihydrotanshinquinone is a natural product that can be isolated from the dried root of S. miltiorrhiza. Methylenedihydrotanshinquinone has anti-inflammatory effect by inhibiting expression of TNF-α, IL-1β, and IL-8.
    Methylenedihydrotanshinquinone
  • HY-126420
    Kansuinine B 57685-46-8 99.0%
    Kansuinine B inhibits IL-6-induced Stat3 activation. Kansuinine B possesses anti-viral activity and could be used in the study for COVID-19.
    Kansuinine B
  • HY-126467
    TA-270 194037-25-7 98%
    TA-270, a novel quinolinone derivative, is a potent inhibitor of 5-lipoxygenase that plays an important role in asthma research.
    TA-270
  • HY-126479
    Carbomycin B 21238-30-2 98%
    Carbomycin B is a macrolide antibiotic.
    Carbomycin B
  • HY-126564
    Ebelactone A 76808-16-7 98%
    Ebelactone A is a mycolic acid β-lactone, which exhibits inhibitory activity for esterase, lipase, fMet aminopeptidase (fMet AP) and PNBase, with IC50s of 56, 3, 8 and 7.5 μM, respectively. Ebelactone A inhibits cutinase, exhibits plants protective potency against Erysiphe graminis.
    Ebelactone A
  • HY-126609
    Emorfazone 38957-41-4 98%
    Emorfazone (Pentoil) is a non-steroidal anti-inflammatory drug with oral activity. Emorfazone can significantly inhibit the release of bradykinin-like substances and kininogen. Emorfazone has anti-inflammatory and analgesic activity.
    Emorfazone
  • HY-126696
    Altromycin D 128461-01-8 98%
    Altromycin D is a Gram-positive antibiotic.
    Altromycin D
  • HY-126715
    Pimelautide 78512-63-7 98%
    Pimelautide (RP 44102), a desmuramyl peptidolipid, is an adjuvant. Pimelautide shows a LD50 of 410 mg/kg (i.v, mouse).
    Pimelautide
  • HY-126716
    Leukotriene C4 methyl ester 73958-10-8 98%
    Leukotriene C4 methyl ester is a methyl ester of leukotriene C4. Leukotriene C4 methyl ester can be used for the research of psoriasis.
    Leukotriene C4 methyl ester
  • HY-126722
    Lipoxin A4 methyl ester 97643-35-1 98%
    Lipoxin A4 methyl ester is a stable synthetic analog of lipoxin with anti-inflammatory properties that can be extracted from arachidonic acid.
    Lipoxin A4 methyl ester
  • HY-126754
    Archangelicin 2607-56-9 98%
    Archangelicin is an inhibitor for cAMP-phosphodiesterase (cAMP-PDE) with IC50 >400 μM. Archangelicin inhibits nuclear factor of activated T cell (NFAT) with IC50 of 9 μM. Archangelicin exhibits antitumor and anti-inflammatory.
    Archangelicin
  • HY-126787
    17-Hydroxyventuricidin A 113204-43-6 98%
    17-Hydroxyventuricidin A (YP-02259L-C) is an antimicrobial compound.17-Hydroxyventuricidin A inhibits the growth of the two tested filamentous fungi (Verticillium dahlia and Fusarium sp.) and of Candida tropicalis R2 CIP203.
    17-Hydroxyventuricidin A
  • HY-126800
    Glycotriosyl glutamine 83235-86-3 98%
    Glycotriosyl glutamine is a synthetic analogue of the Glycopeptide. Glycotriosyl glutamine induces focal glomerulonephritis (FGN) and the appearance of myeloid bodies in the epithelial cells of the podocytes in rats with nephritogenic activity.
    Glycotriosyl glutamine
  • HY-126836
    L-685487 132055-38-0 98%
    L-685487 is a 13-desmethyl derivative of FK506 (HY-13756). L-685487 is promising for research of immunomodulators.
    L-685487
  • HY-126849
    3-Morpholinosydnonimine 33876-97-0 98%
    3-Morpholinosydnonimine (SIN-1) is a spontaneous ROS/RNS generator and peroxynitrite donor. 3-Morpholinosydnonimine is a vasodilator and platelet aggregation inhibitor. 3-Morpholinosydnonimine induces oxidative stress-induced chondrocyte apoptosis and necrosis. 3-Morpholinosydnonimine inhibits the migration, proliferation and neointima formation of vascular smooth muscle cells by inhibiting the expression of annexin A2. In addition, low doses of 3-Morpholinosydnonimine shows protective effects on Zn2+ treated nerve cells.
    3-Morpholinosydnonimine
  • HY-126852
    4-Hydroxy Atorvastatin lactone 163217-70-7 98%
    4-Hydroxy Atorvastatin lactone is a metabolite of Atorvastatin (HY-B0589). Atorvastatin is an orally active HMG-CoA reductase inhibitor, has the ability to effectively decrease blood lipids.
    4-Hydroxy Atorvastatin lactone
Cat. No. Product Name / Synonyms Application Reactivity