2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-106567
    Fluocortin butyl ester 41767-29-7 98%
    Fluocortin butyl ester is a developed corticosteroid compound with no detectable systemic corticosteroid activity when it is used topically. Fluocortin butyl ester appears to be an effective well-tolerated topical steroid useful in the research of perennial rhinitis.
    Fluocortin butyl ester
  • HY-106574
    Ceftobiprole medocaril 376653-43-9 98%
    Ceftobiprole medocaril (BAL5788) is the parenteral proagent of Ceftobiprole (HY-112579). Ceftobiprole is a parenteral pyrrolidinone cephalosporin. Ceftobiprole is a broad-spectrum cephalosporin with high levels of in vitro activity against methicillin- (MRSA) and vancomycin-resistant staphylococci (VRSA) and penicillin-resistant streptococci. Ceftobiprole also inhibits gram-positive and gram-negative pathogens.
    Ceftobiprole medocaril
  • HY-106615
    Dextofisopam 82059-50-5 98%
    Dextofisopam is the R-enantiomer of the homophthalazine tofisopam. Dextofisopam can be studied in research on irritable bowel syndrome and inflammatory bowel disease[1[.
    Dextofisopam
  • HY-106622
    TEI-6122 83058-69-9 98%
    TEI-6122 is a 7-thiaprostaglandin E1 derivative. TEI-6122 can reduce urinary protein and suppressthe increase of blood urea nitrogen. TEI-6122 can inhibit monocyte chemoattractant protein-1 induced chemotaxis. TEI-6122 can be used for the research of inflammation, such as nephritis.
    TEI-6122
  • HY-106630
    Domiodol 61869-07-6 98%
    Domiodol can be studied in research on chronic bronchitis.
    Domiodol
  • HY-106645
    Cloxacepride 65569-29-1 98%
    Cloxacepride is an orally active and potent antiallergic agent. Cloxacepride is a CaM (calmodulin) antagonist. Cloxacepride has anti-PCA (passive cutaneous anaphylaxis) activity.
    Cloxacepride
  • HY-106731
    KT 2-230 134296-41-6 98%
    KT 2-230 is a sodium channel and calcium channel blocker with anti-inflammation effects.
    KT 2-230
  • HY-106754
    FLM-5011 50652-76-1 98%
    FLM-5011 is a lipoxygenase inhibitor. FLM-5011 can diminish myocardial ischaemia injury and shows anti-inflammatory effect. FLM-5011 can be used for the researches of inflammation and cardiovascular disease, such as myocarditis.
    FLM-5011
  • HY-106765
    Thymotrinan 85465-82-3 98%
    Thymotrinan (RGH-0205) is a biologically active fragment of the naturally occurring thymus hormone thymopoietin and a immunomodulating peptide. Thymotrinan exerts similar immunomodulatory activities to TP5 and to affect humoral as well as cellular responses.
    Thymotrinan
  • HY-106785
    Pobilukast 107023-41-6 98%
    Pobilukast is a classical CysLT1 receptor antagonist. Pobilukast can be used for the research of asthma.
    Pobilukast
  • HY-106789
    Plaunotol 64218-02-6 98%
    Plaunotol is an orally active acyclic diterpene alcohol. Plaunotol has antibacterial activity against Helicobacter pylori which causes peptic ulcer . Plaunotol inhibits tumor angiogenesis and cell proliferation. Plaunotol induces apoptosis by activation of caspase 8 and caspase 9 pathways. Plaunotol is a potential anticancer agent against colon cancer .
    Plaunotol
  • HY-106793
    Tiprotimod 105523-37-3 98%
    Tiprotimod (HBW-538) is a synthetic thiazole derivative. Tiprotimod is a potent immunopotentiator for humoral and cell-mediated immune response in animal models.
    Tiprotimod
  • HY-106797
    CV 3611 98829-12-0 98%
    CV 3611 is a potent and orally active free radical scavenger. CV 3611 shows anti-inflammatory, antiarrhythmic and anticancer effects. CV 3611 can be used for the researches of cancer, inflammation and cardiovascular disease, such as hepatocellular carcinoma and acute pancreatitis.
    CV 3611
  • HY-106806
    NZ-107 107186-52-7 98%
    NZ-107 is an orally active leukotriene receptor antagonist. NZ-107 can inhibit anaphylaxis reaction. NZ-107 can be used for the researches of inflammation and immunology.
    NZ-107
  • HY-106837
    Israpafant 117279-73-9 98%
    Israpafant (Y-24180) is a potent, selective and long-acting platelet activation factor (PAF) receptor antagonist with IC50s of 0.84 nM and 3.84 nM against PAF-induced human and rabbit platelet aggregation, respectively. Israpafant stimulates both extracellular Ca2+ influx and intracellular Ca2+ release in prostate cancer cells. Israpafant suppresses the allergic cutaneous reactions including eosinophilia, cytokine production, edema and erythema in mice.
    Israpafant
  • HY-106847
    SDZ-MRL 953 123136-61-8 98%
    SDZ-MRL 953 is a novel immunostimulatory lipid analogue. SDZ-MRL 953 has no pulmonary toxicity and good safety. SDZ-MRL 953 can be used for research on acute lung injury.
    SDZ-MRL 953
  • HY-106849
    Y-26611 143375-60-4 98%
    Y-26611 is an orally active new type of quinolone derivative. Y-26611 exhibits strong phototoxicity under UV irradiation and can significantly induce lipid peroxidation of human red blood cell membrane.
    Y-26611
  • HY-106896
    YM 934 136544-11-1 98%
    YM 934 is a potassium channel opener. YM 934 inhibits neurogenic plasma leakage. YM 934 inhibits airway neurogenic inflammation.
    YM 934
  • HY-106908
    Filaminast 141184-34-1 98%
    WAY-PDA 641 is a potent and preferential PDE-IV inhibitor, with an IC50 of 0.42 μM for canine trachealis PDE-IV. WAY-PDA 641 induces respiratory muscle relaxation and bronchodilation.
    Filaminast
  • HY-106919
    D-20133 146764-26-3 98%
    D-20133 is an orally active Hexadecylphosphocholine analog. D-20133 can both enhance and inhibit antigen-induced histamine release. D-20133 shows antineoplastic activity against small DMBA (HY-W011845)-induced mammary carcinomas.
    D-20133
Cat. No. Product Name / Synonyms Application Reactivity