2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

Related Products

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-149744
    FXb 2408732-52-3
    FXb is an immunizing and functionalized hapten and can be used for protein bioconjugates preparation.
    FXb
  • HY-149752
    Methylthiomcresol-C1-benzoic acid 848486-56-6
    Methylthiomcresol-C1-benzoic acid is a fenthion hapten that can be used for immunoreagent production (protein conjugates and polyclonal antibodies).
    Methylthiomcresol-C1-benzoic acid
  • HY-149753
    Methylthiomcresol-succinaldehydic acid 848486-57-7
    Methylthiomcresol-succinaldehydic acid is a fenthion hapten that can be used for immunoreagent production (protein conjugates and polyclonal antibodies).
    Methylthiomcresol-succinaldehydic acid
  • HY-149754
    Ursodeoxycholic acid 7-N-acetylglucosaminide 145624-10-8
    Ursodeoxycholic acid 7-N-acetylglucosaminide is an immunizing and heterologous hapten.
    Ursodeoxycholic acid 7-N-acetylglucosaminide
  • HY-149772
    Ciguatoxin CTX 3C 148471-85-6
    Ciguatoxin CTX 3C, an immunizing and heterologous hapten, induces a rapid imbalance in neuronal excitability.
    Ciguatoxin CTX 3C
  • HY-149815
    HBV-IN-33
    HBV-IN-33 (C-49), a HBV inhibitor, notably suppresses HBV replication in HepAD38, HepG2-HBV1.3 and HepG2-NTCP cells.
    HBV-IN-33
  • HY-149816
    Anti-inflammatory agent 41 2896204-90-1
    Anti-inflammatory agent 41 (13a) significantly inhibit lipopolysaccharide (LPS)-induced expression of the proinflammatory cytokines IL-6 and TNF-α on J774A.1, THP-1 and LX-2 cells, and inhibits the activation of the NF-κB pathway.
    Anti-inflammatory agent 41
  • HY-149821
    Antifungal agent 50 2896209-33-7
    Antifungal agent 50 is an antifungal agent, displaying MICs <0.063-1 μg/mL.
    Antifungal agent 50
  • HY-149837
    PRO-F
    PRO-F is a photoactivable H2S donor with ROS scavenging ability. PRO-F can be activated by light to produce fluorescent signal, for real-time tracking of released H2S. PRO-F activation doesn’t consume endogenous substances. deliver H2S in an intracellular environment to protect cells from excessive reactive oxygen species (ROS) induced damage. PRO-F shows enhancement on chronic wound healing, researched in diabetic models as well.
    PRO-F
  • HY-149850
    p38 Kinase inhibitor 5 2929285-29-8
    p38 Kinase inhibitor 5 (AA6) is a potent p38 kinase inhibitor with an IC50 of 403.57 nM. p38 Kinase inhibitor 5 has anti-inflammatory activity.
    p38 Kinase inhibitor 5
  • HY-149852
    Anti-osteoporosis agent-3 2944463-16-3
    Anti-osteoporosis agent-3 (Compound 11), a PMSA derivative, is an anti-osteoporosis agent. Anti-osteoporosis agent-3 inhibits osteoclastogenesis with an IC50 value of 322.9 nM in vitro. Anti-osteoporosis agent-3 also blocks the formation of F-action belts and bone resorption.
    Anti-osteoporosis agent-3
  • HY-149943
    PAP-IN-2
    PAP-IN-2 (Compound 35) is a purple acid phosphatase (PAP) inhibitor (Kis: 186 nM). PAP-IN-2 can be used for development of anti-osteoporotic compounds.
    PAP-IN-2
  • HY-149944
    Analgesic agent-2 2983892-65-3
    Analgesic agent-2 is a selective and orally active NaV1.8 Channel inhibitor, with an IC50 of 50.18 nM in HEK293 cells stably expressing human NaV1.8 channel. Analgesic agent-2 has analgesic activity.
    Analgesic agent-2
  • HY-149953
    FABP4-IN-2 2983117-36-6
    FABP4-IN-2 (Compd 10g) is a selective and orally active FABP4 inhibitor with the Ki values of 0.51 μM for FABP4, 33.01 μM for FABP3. FABP4-IN-2 can be used in the research of inflammation-related diseases.
    FABP4-IN-2
  • HY-149961
    Anti-inflammatory agent 40 3043821-37-7
    Anti-inflammatory agent 40 is a potential and orally active anti-malarial and anti-inflammatory agent. Anti-inflammatory agent 40 inhibits carrageenan induced paw swelling in vivo.
    Anti-inflammatory agent 40
  • HY-149971
    XJ02862-S2 3023355-55-4
    XJ02862-S2 shows potent FXR agonistic activity. XJ02862-S2 is a promising lead compound for the research of NAFLD.
    XJ02862-S2
  • HY-149982
    IDO1-IN-22 2126853-16-3
    IDO1-IN-22 (Compound 3) is a IDO1 inhibitor (biochemical hIDO1 IC50: 67.4 nM, HeLa hIDO1 IC50: 17.6 nM). IDO1-IN-22 has excellent antitumor efficacy in LLC xenograft model, as well as desirable pharmacokinetic (PK) profile.
    IDO1-IN-22
  • HY-149984
    MAO-B-IN-21 2956426-18-7
    MAO-B-IN-21 is an excellent MAO-B inhibitor with antioxidant activity and anti-Aβ aggregation activity. MAO-B-IN-21 also exhibits metal-ion chelating ability, anti-neuroinflammation (NO, TNF-α), neuroprotective activity and BBB permeability. MAO-B-IN-21 significantly improves the memory and cognitive impairment in Aβ1-42 induced Alzheimer's disease mice model.
    MAO-B-IN-21
  • HY-150002
    Antibacterial agent 115 2259732-60-8
    Antibacterial agent 115 (Compound 10) is an orally active antibacterial and anti-inflammatory agent.
    Antibacterial agent 115
  • HY-150028
    CB1/2 agonist 2 2772379-97-0
    CB1/2 agonist 2 (compound 23) is a potent non-selective cannabinoid ligand, with Ki values of 3.5 and 1.2 nM, respectively. CB1/2 agonist 2 can behave as a full CB1 agonist and CB2 competitive inverse agonist. CB1/2 agonist 2 shows antinociceptive activity.
    CB1/2 agonist 2
Cat. No. Product Name / Synonyms Application Reactivity