2. Inflammation/Immunology

Inflammation/Immunology

Inflammation/Immunology

Related Products

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The diseases caused by disorders of the immune system fall into two broad categories: immunodeficiency and autoimmunity. Immunotherapy is also often used in the immunosuppressed (such as HIV patients) and people suffering from other immune deficiencies or autoimmune diseases. This includes regulating factors such as IL-2, IL-10, IFN-α. Infection with HIV is characterized not only by development of profound immunodeficiency but also by sustained inflammation and immune activation. Chronic inflammation as a critical driver of immune dysfunction, premature appearance of aging-related diseases, and immune deficiency.

Cat. No. Product Name CAS No. Purity Chemical Structure
  • HY-129466
    PCTR2 1810710-63-4 98%
    PCTR2 is a protectin sulfidoconjugate, which is a pro-resolving mediator that exhibits activity towards inflammation and tissue regeneration.
    PCTR2
  • HY-12946A
    BI 653048 phosphate 1198784-97-2 98%
    BI 653048 phosphate is a selective and orally active nonsteroidal glucocorticoid (GC) agonist with an IC50 value of 55 nM. BI 653048 phosphate inhibits CP1A2, CYP2D6, CYP2C9, CYP2C19 and CYP3A4 isoforms’ activity and reduces affinity for the hERG ion channel (IC50>30 μM). BI 653048 phosphate is extracted from patent WO2005028501A1 (Compound 103), is also a HCV NS3 protease inhibitor that can reduce viral loads infected with the hepatitis C virus.
    BI 653048 phosphate
  • HY-129471
    Arbaprostil 55028-70-1 98%
    Arbaprostil is an orally active PGE1 (HY-B0131) analog. Arbaprostil protects the gastrointestinal mucosa from stomach acid and other irritants, promotes healing rate of gastric ucler through the antisecretory effect.
    Arbaprostil
  • HY-129546
    Eprozinol hydrochloride 27588-43-8 98%
    Eprozinol hydrochloride is a compound with antibronchoconstrictor activity. Eprozinol hydrochloride can be used in the study of bronchospasm.
    Eprozinol hydrochloride
  • HY-129664
    L 683519 132172-14-6 98%
    L 683519, one of the impurities of tacrolimus, is an immunosuppressant. L 683519 can inhibit the activity of FK-506 binding protein.
    L 683519
  • HY-129670
    KMUP-1 81996-46-5
    KMUP-1 is a xanthine derivative with vasodilator activity. KMUP-1 is a inhibitor of phosphodiesterase (PDE) and activator of soluble guanylyl cyclase (sGC). KMUP-1 stimulates NO/sGC/cyclic GMP pathway. KMUP-1 has K+ channels opening activity. KMUP-1 ameliorates ischemia-induced cardiomyocyte apoptosis. KMUP-1 can be used for cardiovascular and anti-inflammatory study.
    KMUP-1
  • HY-129716
    L-693989 138661-20-8 98%
    L-693989 is an orally active water-soluble lipopeptide with anticandidal and antipneumocystis activity. L-693989 is effective in preventing the development of both P. carinii cysts. L-693989 is promising for research of P. carinii pneumonia.
    L-693989
  • HY-129749
    IDO-IN-13 2291164-02-6 98%
    IDO-IN-13 is a potent indoleamine 2,3-dioxygenase 1 (IDO1) inhibitor with an EC50 of 17 nM, extracted from patent WO2019040102A1, example 43.
    IDO-IN-13
  • HY-129764
    Prostaglandin F3α 745-64-2 98%
    Prostaglandin F3α (PGF3α) is an eicosapentaenoic acid (EPA)-derived bioactive lipid mediator that has anti-cancer and anti-inflammatory effects. Prostaglandin F3α is a substrate of ABCC4 with a Km of 12.1 μM. Prostaglandin F3α can be used for the research of diabetes.
    Prostaglandin F3α
  • HY-129944
    MJ33-OH 199106-13-3 98%
    MJ33-OH is a metabolite of MJ33. MJ33 is an active-site-directed, specific, competitive, and reversible phospholipase A2 (PLA2) inhibitor. MJ33 blocks the calcium-independent phospholipase A2 (iPLA2) activity of Prdx6.
    MJ33-OH
  • HY-129953
    9α,11β-Prostaglandin F2α 38432-87-0 98%
    9α,11β-Prostaglandin F2α is an endogenous metabolite present in Urine that can be used for the research of Asthma.
    9α,11β-Prostaglandin F2α
  • HY-130043
    11-O-Methylpseurotin A 956904-34-0 98%
    11-O-Methylpseurotin A is a compound of mixed polyketide synthase–nonribosomal peptide synthetase (PKS/NRPS) origin. 11-O-Methylpseurotin A selectively inhibits a Hof1 deletion strain.
    11-O-Methylpseurotin A
  • HY-13004R
    Maraviroc (Standard) 376348-65-1
    Maraviroc (Standard) is the analytical standard of Maraviroc. This product is intended for research and analytical applications. Maraviroc (UK-427857) is a selective CCR5 antagonist with activity against human HIV.
    Maraviroc (Standard)
  • HY-13004S
    Maraviroc-d6 1033699-22-7 98%
    Maraviroc-d6 (UK-427857-d6) is the deuterium labeled Maraviroc. Maraviroc (UK-427857) is a selective CCR5 antagonist with activity against human HIV.
    Maraviroc-d6
  • HY-130069
    Teicoplanin A2-5 91032-38-1 98%
    Teicoplanin A2-5 is an antibiotic active against Gram-positive aerobic and anaerobic bacteria.
    Teicoplanin A2-5
  • HY-130138
    (5S,6S)-DiHETE 82948-87-6 98%
    (5S,6S)-DiHETE is an enantiomer of (5,6)-DiHETEs.
    (5S,6S)-DiHETE
  • HY-130165
    Tr-PEG8-OH 1144113-16-5
    Tr-PEG8-OH is a non-cleavable 8 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Tr-PEG8-OH is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
    Tr-PEG8-OH
  • HY-13018B
    MRT67307 dihydrochloride 1781882-89-0 98%
    MRT67307 dihydrochloride is a dual inhibitor of the IKKε and TBK-1 with IC50s of 160 and 19 nM, respectively. MRT67307 dihydrochloride also inhibits ULK1 and ULK2 with IC50s of 45 and 38 nM, respectively. MRT67307 dihydrochloride also blocks autophagy in cells.
    MRT67307 dihydrochloride
  • HY-130220
    (±)5-HETE lactone 81517-87-5 98%
    (±)5-HETE lactone is the racemate of 5-HETE lactone. 5-HETE lactone is a metabolite generated by a series of enzymatic reactions of arachidonic acid, and is also a substrate of paraoxonase-1 (PON1). 5-HETE lactone can be used in the study of B cell activation.
    (±)5-HETE lactone
  • HY-130281
    Ianthelliformisamine B diTFA 1643593-29-6 98%
    Ianthelliformisamine B diTFA is a bromotyrosine-derived antibacterial agent. Ianthelliformisamine B diTFA is against E. coli and S. aureus strains with MICs of 14.5 μM and 144.7 μM.
    Ianthelliformisamine B diTFA
Cat. No. Product Name / Synonyms Application Reactivity